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In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of Îł-hydroxybutyrate (GHB) binding.
Toxicology in vitro : an international journal published in association with BIBRA 20170401
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Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.
Toxicology and applied pharmacology 20161215
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Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450.
Toxicology letters 20161116
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Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation.
PloS one 20160101
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Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Scientific reports 20140101
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Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Toxicological sciences : an official journal of the Society of Toxicology 20131201
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Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131001
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Felodipine-diazabicyclo[2.2.2]octane-water (1/1/1).
Acta crystallographica. Section C, Crystal structure communications 20121101
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Antihypertensive effect of low-frequency transcutaneous electrical nerve stimulation (TENS) in comparison with drug treatment.
Blood pressure 20121001
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Optimizing the ability of PVP/PEG mixtures to be used as appropriate carriers for the preparation of drug solid dispersions by melt mixing technique using artificial neural networks: I.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120901
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Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions.
Journal of pharmaceutical sciences 20120801
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QSAR model for human pregnane X receptor (PXR) binding: screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity.
Toxicology and applied pharmacology 20120801
-
A mechanism-based approach for absorption modeling: the Gastro-Intestinal Transit Time (GITT) model.
The AAPS journal 20120601
-
Moringa coagulant as a stabilizer for amorphous solids: Part I.
AAPS PharmSciTech 20120601
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Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal of medicinal chemistry 20120524
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Microstructural investigation to the controlled release kinetics of monolith osmotic pump tablets via synchrotron radiation X-ray microtomography.
International journal of pharmaceutics 20120510
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Enhancement of felodipine dissolution rate through its incorporation into Eudragit® E-PHB polymeric microparticles: in vitro characterization and investigation of absorption in rats.
Journal of pharmaceutical sciences 20120401
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Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
European journal of clinical investigation 20120301
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ToF-SIMS analysis of chemical heterogenities in inkjet micro-array printed drug/polymer formulations.
Journal of materials science. Materials in medicine 20120201
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[Analysis and evaluation of the impurity of felodipine and its tablets].
Yao xue xue bao = Acta pharmaceutica Sinica 20120201
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Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Bioorganic & medicinal chemistry letters 20120115
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Role of cyclodextrin complexation in felodipine-sustained release matrix tablets intended for oral transmucosal delivery: in vitro and ex vivo characterization.
Pharmaceutical development and technology 20120101
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Effect of felodipine with irbesartan or metoprolol on sexual function and oxidative stress in women with essential hypertension.
Journal of hypertension 20120101
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Inkjet printing as a novel medicine formulation technique.
Journal of controlled release : official journal of the Controlled Release Society 20111210
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Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma.
Investigational new drugs 20111201
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Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology 20111201
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Compositional analysis of low quantities of phase separation in hot-melt-extruded solid dispersions: a combined atomic force microscopy, photothermal fourier-transform infrared microspectroscopy, and localised thermal analysis approach.
Pharmaceutical research 20110901
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Application of pharmaceutical QbD for enhancement of the solubility and dissolution of a class II BCS drug using polymeric surfactants and crystallization inhibitors: development of controlled-release tablets.
AAPS PharmSciTech 20110901
-
Development of a high-performance liquid chromatography method for simultaneous determination of pioglitazone and felodipine in pig serum: application to pharmacokinetic study.
Biomedical chromatography : BMC 20110801
-
Dissolution and precipitation behavior of amorphous solid dispersions.
Journal of pharmaceutical sciences 20110801
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The stability of solid dispersions of felodipine in polyvinylpyrrolidone characterized by nanothermal analysis.
International journal of pharmaceutics 20110729
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Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: in vitro, ex vivo, and in vivo characterization.
Drug delivery 20110701
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Influence of particle size on the ultraviolet spectrum of particulate-containing solutions: implications for in-situ concentration monitoring using UV/Vis fiber-optic probes.
Pharmaceutical research 20110701
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Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals.
Microvascular research 20110701
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The effect of metoprolol alone and combined metoprolol-felodipin on the digital microcirculation of patients with primary Raynaud's syndrome.
Microvascular research 20110701
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Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.
Journal of medicinal chemistry 20110609
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Is a systolic blood pressure target <140 mmHg indicated in all hypertensives? Subgroup analyses of findings from the randomized FEVER trial.
European heart journal 20110601
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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor.
Bioorganic & medicinal chemistry letters 20110515
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Development of push-pull osmotic tablets using chitosan-poly(acrylic acid) interpolymer complex as an osmopolymer.
AAPS PharmSciTech 20110301
-
Identification of clinically used drugs that activate pregnane X receptors.
Drug metabolism and disposition: the biological fate of chemicals 20110101
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Pharmacokinetics of felodipine extended-release tablets in healthy Taiwanese subjects: a retrospective review.
Arzneimittel-Forschung 20110101
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[Calcium channels blocker felodipin in the treatment of patients with arterial hypertension and chronic cardial failure with preserved cardiac output].
Terapevticheskii arkhiv 20110101
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Pharmacokinetic and antihypertensive profile of amlodipine and felodipine-ER in younger versus older patients with hypertension.
Journal of cardiovascular pharmacology 20101201
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
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[Therapeutic effect on essential hypertension treated with combined therapy of acupuncture and medication].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20101101
-
A thermal analysis method to predict the complete phase diagram of drug-polymer solid dispersions.
International journal of pharmaceutics 20101031
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Effects of individual risk factors on the residual risk of cardiovascular events in a population of treated Chinese patients with hypertension: data from the Felodipine Event Reduction (FEVER) study.
Journal of hypertension 20101001
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Biorelevant media to simulate fluids in the ascending colon of humans and their usefulness in predicting intracolonic drug solubility.
Pharmaceutical research 20101001
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Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values.
European journal of medicinal chemistry 20101001
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Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study.
Pharmaceutical research 20100901
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A novel method to measure the glass and melting transitions of pharmaceutical powders.
International journal of pharmaceutics 20100830
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[Effect between felodipine plus irbesartan and felodipine plus metoprolol regimen on the sexual function in young and middle-aged women with hypertension].
Zhonghua xin xue guan bing za zhi 20100801
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Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.
Drug metabolism and disposition: the biological fate of chemicals 20100601
-
Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100501
-
Publication bias on clinical studies of pharmacokinetic interactions between felodipine and grapefruit juice.
Die Pharmazie 20100501
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Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture.
Molecular pharmaceutics 20100405
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Understanding the behavior of amorphous pharmaceutical systems during dissolution.
Pharmaceutical research 20100401
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Blockade of calcium channels and AT1 receptor prevents the hypertensive effect of calcilytic NPS 2143 in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401
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A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle.
Proceedings of the National Academy of Sciences of the United States of America 20100223
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Interaction between felodipine and bovine serum albumin: fluorescence quenching study.
Luminescence : the journal of biological and chemical luminescence 20100101
-
Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone).
Journal of pharmaceutical sciences 20100101
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Felodipine-induced eruptive telangiectasia following mastectomy and radiotherapy.
The British journal of dermatology 20100101
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[Fixed combinations of antihypertensive medications--new opportunity in treatment of hypertension].
Lijecnicki vjesnik 20100101
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[Calcium antagonists: on the way to expanding the indications].
Terapevticheskii arkhiv 20100101
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[Comparative eficacy of antihypertensive therapy in patients with arterial hypertension and various sensitivity to salt].
Kardiologiia 20100101
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Targeting the IL-6 dependent phenotype can identify novel therapies for cholangiocarcinoma.
PloS one 20100101
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Effects of polymer type and storage relative humidity on the kinetics of felodipine crystallization from amorphous solid dispersions.
Pharmaceutical research 20091201
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Synthesis of 4-thiophen-2'-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel.
Bioorganic & medicinal chemistry 20091201
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Evaluation of drug-polymer miscibility in amorphous solid dispersion systems.
Pharmaceutical research 20091101
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[Impact of antihypertensive medication timing on degree and stability of blood pressure lowering in patients with essential hypertension].
Zhonghua xin xue guan bing za zhi 20091101
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Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Bioorganic & medicinal chemistry 20091001
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
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Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.
The Journal of pharmacology and experimental therapeutics 20090901
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[Effect of felodipine on the expression of NF-kappaB in rat model of atherosclerosis].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901
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Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens.
Die Pharmazie 20090801
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Preparation of N-maleoylchitosan nanocapsules for loading and sustained release of felodipine.
Biomacromolecules 20090713
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Extended release felodipine self-nanoemulsifying system.
AAPS PharmSciTech 20090601
-
Simulation of gastric lipolysis and prediction of felodipine release from a matrix tablet in the fed stomach.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512
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Pair distribution function X-ray analysis explains dissolution characteristics of felodipine melt extrusion products.
Journal of pharmaceutical sciences 20090401
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Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome.
Journal of endocrinological investigation 20090401
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The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment.
International journal of cardiology 20090220
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Chloride channels as drug targets.
Nature reviews. Drug discovery 20090201
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[The use of felodipine in ambulatory practice: assessment of clinical efficacy and compliance in patients with arterial hypertension].
Kardiologiia 20090101
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A cell-based assay for screening of antidotes to, and antivenom against Chironex fleckeri (box jellyfish) venom.
Journal of pharmacological and toxicological methods 20090101
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From Tritace to Tri-Plen - the South African journey.
Cardiovascular journal of Africa 20090101
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[Structural-functional properties of the vascular wall in hypertensive patients with coronary heart disease: effects of felodipin and perindopril].
Terapevticheskii arkhiv 20090101
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Vasospasm-induced polymorphic ventricular tachycardia.
The Canadian journal of cardiology 20081201
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Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
Blood pressure. Supplement 20081201
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[Curative effects on mild to moderate primary hypertension and influence on pulse wave velocity of slow releasing felodipine].
Zhonghua yi xue za zhi 20081118
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal of medicinal chemistry 20081113
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Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Journal of medicinal chemistry 20081009
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Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001
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Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation.
Acta pharmacologica Sinica 20080901
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Effect of poloxamer on the dissolution of felodipine and preparation of controlled release matrix tablets containing felodipine.
Archives of pharmacal research 20080801
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Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
The Journal of biological chemistry 20080620
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Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal of medicinal chemistry 20080612
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Effect and tolerability of felodipine ER (Feloten) in the treatment of hypertension assessed by office blood pressure and home blood pressure.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080501
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Ability of different polymers to inhibit the crystallization of amorphous felodipine in the presence of moisture.
Pharmaceutical research 20080401
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Recrystallization of nifedipine and felodipine from amorphous molecular level solid dispersions containing poly(vinylpyrrolidone) and sorbed water.
Pharmaceutical research 20080301
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Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.
Journal of pharmaceutical and biomedical analysis 20080213
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Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells.
Toxicology 20080203
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Molecular mechanisms of felodipine suppressing atherosclerosis in high-cholesterol-diet apolipoprotein E-knockout mice.
Journal of cardiovascular pharmacology 20080201
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Effects of extended-release felodipine on endothelial vasoactive substances in patients with essential hypertension.
Clinical chemistry and laboratory medicine 20080101
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Felodipine reduces cardiac expression of IL-18 and perivascular fibrosis in fructose-fed rats.
Molecular medicine (Cambridge, Mass.) 20080101
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[Efficacy of long acting calcium antagonist felodipine in smoking women with essential arterial hypertension].
Kardiologiia 20080101
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[Efficacy, safety and tolerance of Felodipine controlled release tablets and Felodipine controlled release tablets associated combination therapy in the treatment of mild to moderate essential hypertension in China].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20071218
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Calorimetric study and modeling of molecular mobility in amorphous organic pharmaceutical compounds using a modified Adam-Gibbs approach.
The journal of physical chemistry. B 20071122
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[Preparation of transdermal drug delivery system of felodipine-metoprolol and its bioavailability in rabbits].
Yao xue xue bao = Acta pharmaceutica Sinica 20071101
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The influence of hydro-alcoholic media on hypromellose matrix systems.
Drug development and industrial pharmacy 20071001
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Amorphous drug nanosuspensions. 3. Particle dissolution and crystal growth.
Langmuir : the ACS journal of surfaces and colloids 20070911
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Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists.
The Journal of pharmacology and experimental therapeutics 20070801
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Combining SEM, TEM, and micro-Raman techniques to differentiate between the amorphous molecular level dispersions and nanodispersions of a poorly water-soluble drug within a polymer matrix.
International journal of pharmaceutics 20070801
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Different roles of pummelo furanocoumarin and cytochrome P450 3A5*3 polymorphism in the fate and action of felodipine.
Current drug metabolism 20070801
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Simultaneous determination of nitrendipine and one of its metabolites in plasma samples by gas chromatography with electron-capture detection.
Journal of pharmaceutical and biomedical analysis 20070727
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Structure-activity relationship of 1,4-dihydropyridines as potentiators of the cystic fibrosis transmembrane conductance regulator chloride channel.
Molecular pharmacology 20070701
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Investigation of the release mechanism of a sparingly water-soluble drug from solid dispersions in hydrophilic carriers based on physical state of drug, particle size distribution and drug-polymer interactions.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070601
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The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501
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Estimation of intragastric solubility of drugs: in what medium?
Pharmaceutical research 20070501
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Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.
Circulation 20070417
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Determination of gambogic acid in dog plasma by high-performance liquid chromatography for a pharmacokinetic study.
Biomedical chromatography : BMC 20070301
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Lercanidipine in the treatment of hypertension.
The Annals of pharmacotherapy 20070301
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The in vitro vascular effects of two chirodropid (Chironex fleckeri and Chiropsella bronzie) venoms.
Toxicology letters 20070110
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Photophysics and photochemical studies of 1,4-dihydropyridine derivatives.
Photochemistry and photobiology 20070101
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[The FEVER (Felodipine EVEnt Reduction) trial; a randomised, double-blind, placebo-controlled trial in Chinese hypertensive patients].
Vnitrni lekarstvi 20070101
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Comparison in vitro felodipine release rate from the original versus generic product with controlled release of the drug.
Medicina (Kaunas, Lithuania) 20070101
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[Effects of serotonin on reactivity of ocular vasculature].
Oftalmologia (Bucharest, Romania : 1990) 20070101
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Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine.
Journal of pharmaceutical sciences 20061201
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Preparation of a solid dispersion of felodipine using a solvent wetting method.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061001
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A comparison of the physical stability of amorphous felodipine and nifedipine systems.
Pharmaceutical research 20061001
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Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.
Pharmaceutical research 20061001
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Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.
Clinical and experimental hypertension (New York, N.Y. : 1993) 20061001
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Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice.
International journal of pharmaceutics 20060817
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Application of PVP/HPMC miscible blends with enhanced mucoadhesive properties for adjusting drug release in predictable pulsatile chronotherapeutics.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060801
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Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060601
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FEVER study: a trial further supporting the concept of a blood pressure-independent stroke protective effect by dihydropyridines.
Journal of hypertension 20060601
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A small-molecule screen in C. elegans yields a new calcium channel antagonist.
Nature 20060504
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Micronization and microencapsulation of felodipine by supercritical carbon dioxide.
Journal of microencapsulation 20060501
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Effect of grapefruit juice in relation to human pharmacokinetic study.
Current clinical pharmacology 20060501
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Felodipine nanodispersions as active core for predictable pulsatile chronotherapeutics using PVP/HPMC blends as coating layer.
International journal of pharmaceutics 20060426
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Impaired capacity for stimulated fibrinolysis in primary hypertension is restored by antihypertensive therapy.
Hypertension (Dallas, Tex. : 1979) 20060401
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A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT).
American journal of hypertension 20060401
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CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension.
Pharmacogenomics 20060401
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Initiation of hypertension treatment with a fixed-dose combination or its monocomponents -- does it really matter?
International journal of clinical practice 20060301
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AT1 receptor antagonism improves endothelial dysfunction in postmenopausal women.
Maturitas 20060120
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Sympatho-excitatory responses to once-daily dihydropyridines in young versus older hypertensive patients: amlodipine versus felodipine extended release.
Journal of hypertension 20060101
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Hypertensive urgency.
Journal of clinical hypertension (Greenwich, Conn.) 20060101
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Comparative study of barnidipine and felodipine in Chinese patients with essential hypertension.
The Journal of international medical research 20060101
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A review of calcium channel antagonists in the treatment of pediatric hypertension.
Paediatric drugs 20060101
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Thermal stability of 1,4-dihydropyridine derivatives in solid state.
Acta poloniae pharmaceutica 20060101
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More heat to support aggressive blood pressure lowering: the FEVER study.
Journal of hypertension 20051201
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The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients.
Journal of hypertension 20051201
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Calcium channel antagonists and inhibition of human sphincter of Oddi contractions.
Scandinavian journal of gastroenterology 20051201
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Impact of the intragastric location of extended release tablets on food interactions.
Journal of controlled release : official journal of the Controlled Release Society 20051128
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Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction.
American journal of hypertension 20051001
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Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Bioorganic & medicinal chemistry letters 20050915
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Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process.
International journal of pharmaceutics 20050914
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Dihydropyridines, felodipine, and PHARMAC.
The New Zealand medical journal 20050715
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Felodipine-influenced gingival enlargement in an uncontrolled type 2 diabetic patient.
Journal of periodontology 20050701
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Miscibility behavior and formation mechanism of stabilized felodipine-polyvinylpyrrolidone amorphous solid dispersions.
Drug development and industrial pharmacy 20050701
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Prediction of genotoxicity of chemical compounds by statistical learning methods.
Chemical research in toxicology 20050601
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Renoprotective therapy: is it blood pressure or albuminuria that matters?
Lancet (London, England) 20050301
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Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial.
Lancet (London, England) 20050301
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[The effect and mechanism of felodipine and valsartan on a novel salt-sensitive hypertensive rat induced by sensory denervation].
Zhonghua xin xue guan bing za zhi 20050301
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Characteristics of felodipine-located poly(epsilon-caprolactone) microspheres.
Journal of microencapsulation 20050301
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Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.
Hypertension research : official journal of the Japanese Society of Hypertension 20050301
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Drug interactions with grapefruit juice.
Obstetrics and gynecology 20050201
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Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125
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Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects.
European journal of clinical pharmacology 20050101
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Examination of 209 drugs for inhibition of cytochrome P450 2C8.
Journal of clinical pharmacology 20050101
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Retrospective evaluation of a possible interaction between warfarin and levofloxacin.
Pharmacotherapy 20050101
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[Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].
Archiwum medycyny sadowej i kryminologii 20050101
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Urinary excretion of aquaporin-2 after furosemide and felodipine in healthy humans.
Scandinavian journal of clinical and laboratory investigation 20050101
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Ramipril/felodipine extended-release fixed-dose combination: a review of its use in the management of essential hypertension.
Drugs 20050101
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Drug-associated gingival enlargement: case report and review of aetiology, management and evidence-based outcomes of treatment.
Journal of the New Zealand Society of Periodontology 20050101
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Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humans.
Clinical pharmacology and therapeutics 20041201
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The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.
Endocrine 20041101
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[Gingival hyperplasia and calcium antagonists].
Ugeskrift for laeger 20041018
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6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect.
Clinical pharmacology and therapeutics 20040601
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Nelfinavir and felodipine: a cytochrome P450 3A4-mediated drug interaction.
Clinical pharmacology and therapeutics 20040401
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The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.
American journal of hypertension 20040301
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Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
Pharmaceutical research 20040301
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Determination of the lack of a drug interaction between azithromycin and warfarin.
Pharmacotherapy 20040201
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[Nicergoline-induced Prinzmetal angina. 'Heartache' instead of headache].
Orvosi hetilap 20040104
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Adherence to calcium channel blocker therapy in older adults: a comparison of amlodipine and felodipine.
The Journal of international medical research 20040101
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[Efficacy and tolerability of felodipine based antihypertensive therapy in hospitalized patients with hypertension].
Kardiologiia 20040101
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Calcium channel blockers (felodipine) and pediatric essential hypertension.
Current hypertension reports 20031201
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Evaluation of a therapeutic conversion from amlodipine to felodipine.
Pharmacotherapy 20031101
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Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine.
Drug metabolism and disposition: the biological fate of chemicals 20030901
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Evaluation of polar lipid-hydrophilic polymer microparticles.
International journal of pharmaceutics 20030827
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A comparative analysis of amlodipine and felodipine in a military outpatient population: efficacy, outcomes, and cost considerations.
Military medicine 20030701
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Clinical trial of extended-release felodipine in pediatric essential hypertension.
Pediatric nephrology (Berlin, Germany) 20030601
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Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.
Journal of the American Society of Nephrology : JASN 20030601
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Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.
Clinical pharmacology and therapeutics 20030601
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Health economics in the Hypertension Optimal Treatment (HOT) study: costs and cost-effectiveness of intensive blood pressure lowering and low-dose aspirin in patients with hypertension.
Journal of internal medicine 20030401
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Can the USP paddle method be used to represent in-vivo hydrodynamics?
The Journal of pharmacy and pharmacology 20030401
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Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension.
Hypertension (Dallas, Tex. : 1979) 20030301
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[The effect of analysed hypotensive drugs on certain metabolic parameters].
Polskie Archiwum Medycyny Wewnetrznej 20030301
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Sensitive spectrophotometric determination of amlodipine and felodipine using iron(III) and ferricyanide.
Farmaco (Societa chimica italiana : 1989) 20030201
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MMW Fortschritte der Medizin 20030123
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Different drug classes have variable effects on blood pressure depending on the time of day.
American journal of hypertension 20030101
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The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs.
Journal of clinical hypertension (Greenwich, Conn.) 20030101
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In vitro release of felodipine from original brand and generic products.
Arzneimittel-Forschung 20030101
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Comparative effect of lercanidipine, felodipine, and nifedipine GITS on blood pressure and heart rate in patients with mild to moderate arterial hypertension: the Lercanidipine in Adults (LEAD) Study.
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[Severe felodipine and theophylline poisoning successfully treated by 4-aminopyridine: a case report].
Przeglad lekarski 20030101
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Chitosan microparticle preparation for controlled drug release by response surface methodology.
Journal of microencapsulation 20030101
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Safety and efficacy of therapeutically equivalent doses of sustained-release formulations of isradipine and felodipine.
Congestive heart failure (Greenwich, Conn.) 20030101
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Pharmacodynamic interactions of levosimendan and felodipine in patients with coronary heart disease.
Cardiovascular drugs and therapy 20030101
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Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril.
The Canadian journal of cardiology 20021201
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Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR.
Biochimica et biophysica acta 20021021
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Evaluation of controlled-release polar lipid microparticles.
International journal of pharmaceutics 20020905
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Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.
Clinical pharmacology and therapeutics 20020901
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Acute effects of vasoactive drug treatment on brachial artery reactivity.
Journal of the American College of Cardiology 20020821
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Dihydropyridines are not substitutable without careful monitoring.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801
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[The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20020801
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Angiotensin II type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction.
Arteriosclerosis, thrombosis, and vascular biology 20020701
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A comparison of candesartan, felodipine, and their combination in the treatment of elderly patients with systolic hypertension.
American journal of hypertension 20020601
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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Effects of thyroid replacement therapy on arterial blood pressure in patients with hypertension and hypothyroidism.
American heart journal 20020401
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Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
The Journal of pharmacology and experimental therapeutics 20020301
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Calcium channel blockade with felodipine does not affect metabolic coronary vasodilation in patients with coronary artery disease.
Journal of cardiovascular pharmacology 20020201
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A stability indicating LC method for felodipine.
Journal of pharmaceutical and biomedical analysis 20020201
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Enantioselective determination of felodipine in human plasma by chiral normal-phase liquid chromatography and electrospray ionisation mass spectrometry.
Journal of pharmaceutical and biomedical analysis 20020115
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Effect of felodipine on tacrolimus pharmacokinetics in a renal transplant recipient.
Transplantation 20020115
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Felodipine inhibits nuclear translocation of p42/44 mitogen-activated protein kinase and human smooth muscle cell growth.
Cardiovascular research 20020101
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Cutaneous drug reaction case reports: from the world literature.
American journal of clinical dermatology 20020101
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Influence of hydrodynamics and particle size on the absorption of felodipine in labradors.
Pharmaceutical research 20020101
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[Prospects of use of the combined preparation logimax in patients with essential hypertension].
Terapevticheskii arkhiv 20020101
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Efficacy and safety of barnidipine compared with felodipine in the treatment of hypertension in Chinese patients.
The Journal of international medical research 20020101
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IgA nephropathy in a patient with polycythemia vera. Clinical manifestation of chronic renal failure and heavy proteinuria.
American journal of nephrology 20020101
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Smooth blood pressure control obtained with extended-release felodipine in elderly patients with hypertension: evaluation by 24-hour ambulatory blood pressure monitoring.
Drugs & aging 20020101
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Preparation and characterization of drug-loaded polymethacrylate microspheres by an emulsion solvent evaporation method.
Journal of microencapsulation 20020101
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Influence of antihypertensive treatment with perindopril, pindolol or felodipinon plasma leptin concentration in patients with essential hypertension.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101
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Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.
Fundamental & clinical pharmacology 20011201
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The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101
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One-year study of felodipine or placebo for stage 1 isolated systolic hypertension.
Hypertension (Dallas, Tex. : 1979) 20011101
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Photodistributed felodipine-induced facial telangiectasia.
Journal of the American Academy of Dermatology 20010801
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Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.
Journal of human hypertension 20010801
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Reduction in diastolic blood pressure and cardiovascular mortality in nondiabetic hypertensive patients. A reanalysis of the HOT study.
Arquivos brasileiros de cardiologia 20010801
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Polymorphism of racemic felodipine and the unusual series of solid solutions in the binary system of its enantiomers.
Journal of pharmaceutical sciences 20010701
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Deutsche medizinische Wochenschrift (1946) 20010511
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Investigation of the felodipine glassy state by atomic force microscopy.
International journal of pharmaceutics 20010507
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Efficacy and safety of losartan/hydrochlorothiazide in patients with severe hypertension.
The American journal of cardiology 20010315
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Mechanism of CGRP-induced relaxation in rat intramural coronary arteries.
British journal of pharmacology 20010301
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Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010301
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Normal-phase TLC separation of enantiomers of 1.4-dihydropyridine derivatives.
Drug development and industrial pharmacy 20010201
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Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.
Clinical pharmacology and therapeutics 20010101
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Comparison of the time courses and potencies of the vasodilator effects of nifedipine and felodipine in the human forearm.
Blood pressure 20010101
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A randomised trial to compare the efficacy and safety of Felodipine (Plendil) and Nifedipine (Adalat) retard in patients with mild-to-moderate hypertension.
West African journal of medicine 20010101
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Stroke precipitated by moderate blood pressure reduction.
The Journal of emergency medicine 20001101
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Losartan: a review of its use, with special focus on elderly patients.
Drugs & aging 20000301
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Low Dose Combination Therapy vs. High Dose Monotherapy in the Management of Hypertension.
Journal of clinical hypertension (Greenwich, Conn.) 19991101
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Improved tolerability of felodipine compared with amlodipine in elderly hypertensives: a randomised, double-blind study in 535 patients, focusing on vasodilatory adverse events. The International Study Group.
International journal of clinical practice 19980901
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Significance of blood pressure levels achieved with felodipine anti-hypertensive treatment on cardiovascular structure and function changes.
Journal of human hypertension 19980701
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A comparison of nisoldipine coat-core and felodipine in the treatment of mild-to-moderate hypertension.
International journal of clinical practice 19980601
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Benazepril versus felodipine as supplement to bendroflumethiazide: evaluation by office and ambulatory blood pressure.
Blood pressure monitoring 19980401
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Prevention of left ventricular hypertrophy by ACE-inhibitor, ramipril in comparison with calcium-channel antagonist, felodipine.
International journal of cardiology 19980131
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Influence of felodipine on experimental seizures and activity of different antiepileptic drugs in mice.
Polish journal of pharmacology 19980101
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Effect of the calcium antagonist felodipine as supplementary vasodilator therapy in patients with chronic heart failure treated with enalapril: V-HeFT III. Vasodilator-Heart Failure Trial (V-HeFT) Study Group.
Circulation 19970805
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Verapamil accelerates the transition to heart failure in obese, hypertensive, female SHHF/Mcc-fa(cp) rats.
Journal of cardiovascular pharmacology 19970601
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Cardiovascular effects of a low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.
British journal of pharmacology 19970501
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Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring.
The Netherlands journal of medicine 19970101
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Felodipine in the treatment of severe refractory hypertension.
Journal of human hypertension 19960901
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Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension.
Drugs 19960501
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Does prophylactic treatment with felodipine, a calcium antagonist, prevent low-osmolar contrast-induced renal dysfunction in hydrated diabetic and nondiabetic patients with normal or moderately reduced renal function?
Scandinavian journal of urology and nephrology 19960201
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Global efficacy and tolerability of losartan, an angiotensin II subtype 1-receptor antagonist, in the treatment of hypertension.
Blood pressure. Supplement 19960101
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Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701
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Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.
The American journal of cardiology 19950415
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Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension.
Drugs 19950401
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Mono- and combination therapy with felodipine or enalapril in elderly patients with systolic hypertension.
Blood pressure 19940301
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Efficacy and tolerability of extended-release felodipine and extended-release nifedipine in patients with mild-to-moderate essential hypertension.
Clinical therapeutics 19940101
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Comparison of effects of felodipine versus hydrochlorothiazide on arterial diameter and pulse-wave velocity in essential hypertension.
The American journal of cardiology 19931001
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General toxicity of the new calcium antagonist felodipine in dogs.
Arzneimittel-Forschung 19930701
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A multicenter comparison of isradipine and felodipine in the treatment of mild-to-moderate hypertension. The Physician's Study Group.
American journal of hypertension 19930301
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Long-term effects of felodipine in patients with reduced renal function.
Kidney international. Supplement 19920501
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Felodipine clinical pharmacokinetics.
Clinical pharmacokinetics 19911201
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DICP : the annals of pharmacotherapy 19911101
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Beta-adrenergic receptors and reflex tachycardia after single and repeated felodipine administration in essential hypertension.
Journal of cardiovascular pharmacology 19910601
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Felodipine in combination with a beta-adrenoceptor blocker as an effective substitute for triple therapy in severe hypertension. The Australian Felodipine Multicentre Study Group.
European journal of clinical pharmacology 19910101
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Extended release felodipine in essential hypertension. Variations in blood pressure during whole-day continuous ambulatory recording.
American journal of hypertension 19910101
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Acute effects on exercise tolerance of felodipine and diltiazem, alone and in combination, in stable effort angina.
European heart journal 19910101
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Felodipine ER formulation in the treatment of mild hypertension: efficacy and tolerability vs placebo.
British journal of clinical pharmacology 19901001
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The influence of infusion rate on the hemodynamic effects of felodipine.
Clinical pharmacology and therapeutics 19900901
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The efficacy and tolerability of long-term felodipine treatment in hypertension. The Scandinavian Multicenter Group.
Cardiovascular drugs and therapy 19900601
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Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.
The Medical journal of Australia 19890904
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Drugs 19881001
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Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.
Journal of cardiovascular pharmacology 19880701
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A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.
European journal of clinical pharmacology 19880101
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Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.
Journal of cardiovascular pharmacology 19871001
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Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.
Journal of cardiovascular pharmacology 19870101
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Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.
Drugs 19870101
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Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.
Drugs 19870101
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Felodipine compared to nifedipine as 'third-line drug' in resistant hypertension.
Angiology 19861101
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Renal and antihypertensive effects of felodipine in hypertensive patients.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201
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Felodipine can replace minoxidil in the treatment of refractory hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201
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Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR.
European journal of pharmacology 19850711
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Antihypertensive effect of felodipine combined with beta-blockade. A comparison between 2 and 3 daily dosages.
Drugs 19850101
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Comparative trial of felodipine and nifedipine in refractory hypertension.
Drugs 19850101
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Effects of felodipine on resistance and capacitance vessels in patients with essential hypertension.
Drugs 19850101
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Haemodynamic effects of single-dose felodipine in normal man.
Drugs 19850101
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Hemodynamic effects of felodipine at rest and during exercise in exertional angina pectoris.
The American journal of cardiology 19830901