7295-76-3 | 3-Methoxypyridine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$6.00	$4.00
5g	≥98%	in stock	$15.00	$10.00
10g	98%	in stock	$24.00	$17.00
25g	≥98%	in stock	$56.00	$39.00
100g	97%	in stock	$206.00	$144.00
500g	98%	in stock	$641.00	$449.00

Description

• Catalog Number: AB44625
• Chemical Name: 3-Methoxypyridine
• CAS Number: 7295-76-3
• Molecular Formula: C6H7NO
• Molecular Weight: 109.1259
• MDL Number: MFCD00673022
• SMILES: COc1cccnc1

Computed Properties

• Complexity: 65.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1

Upstream Synthesis Route

3-Methoxypyridine, also known as 3-picoline, is a valuable chemical compound widely utilized in various chemical synthesis processes. Its unique structure and properties make it a versatile building block in organic chemistry.1. As a versatile building block: 3-Methoxypyridine serves as a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Its functional group allows for easy modification, making it a key component in the construction of complex organic molecules.2. Cross-coupling reactions: 3-Methoxypyridine is commonly used in cross-coupling reactions as a nucleophilic coupling partner. It can participate in various catalytic processes to form carbon-carbon or carbon-heteroatom bonds, enabling the synthesis of diverse chemical compounds.3. Catalysis and functional group transformations: 3-Methoxypyridine can act as a ligand in transition metal-catalyzed reactions, facilitating efficient and selective transformations of organic substrates. Its presence can enhance reaction rates and yields, making it an essential tool in modern synthetic chemistry.Overall, the application of 3-Methoxypyridine in chemical synthesis plays a crucial role in the development of new materials, drugs, and agrochemicals. Its versatility and reactivity make it a valuable tool for chemists seeking to access a wide range of complex molecules efficiently and selectively.

Literature

• Synthesis, in vivo occupancy, and radiolabeling of potent phosphodiesterase subtype-10 inhibitors as candidates for positron emission tomography imaging.

  Journal of medicinal chemistry 20110825

• Development and validation of a specific and sensitive GC-FID method for the determination of impurities in 5-chlorovaleroyl chloride.

  Journal of pharmaceutical and biomedical analysis 20101102

• Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease.

  Journal of medicinal chemistry 20081127

• Pyridine-catalyzed stereoselective addition of acyclic 1,2-diones to acetylenic esters: synthetic and theoretical studies of an unprecedented rearrangement.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Reactions of sulphate radicals with substituted pyridines: a structure-reactivity correlation analysis.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20071203

• Benzyl ether structure-activity relationships in a series of ketopiperazine-based renin inhibitors.

  Bioorganic & medicinal chemistry letters 20051101

• Characterization of endoperoxide and hydroperoxide intermediates in the reaction of pyridoxine with singlet oxygen.

  Journal of the American Chemical Society 20021016