74165-73-4 | 1-Amino-2-hydroxyindane

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$201.00	$141.00
1g	95%	in stock	$479.00	$335.00
5g	95%	in stock	$1,535.00	$1,074.00

Description

• Catalog Number: AB57822
• Chemical Name: 1-Amino-2-hydroxyindane
• CAS Number: 74165-73-4
• Molecular Formula: C9H11NO
• Molecular Weight: 149.1897
• MDL Number: MFCD00053472
• SMILES: NC1C(O)Cc2c1cccc2

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Undefined Atom Stereocenter Count: 2
• XLogP3: 0.2

Literature

• Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols.

  Bioorganic & medicinal chemistry 20121001

• Stereocontrolled synthesis of substituted chiral piperidines via one-pot asymmetric 6π-azaelectrocyclization: asymmetric syntheses of (-)-dendroprimine, (+)-7-epidendroprimine, (+)-5-epidendroprimine, and (+)-5,7-epidendroprimine.

  The Journal of organic chemistry 20120217

• The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols.

  Organic & biomolecular chemistry 20120121

• The role of weak hydrogen bonds in chiral recognition.

  Physical chemistry chemical physics : PCCP 20111028

• Amino-indanol-catalyzed asymmetric Michael additions of oxindoles to protected 2-amino-1-nitroethenes for the synthesis of 3,3'-disubstituted oxindoles bearing α,β-diamino functionality.

  The Journal of organic chemistry 20110520

• Chiral recognition in jet-cooled complexes of (1R,2S)-(+)-cis-1-amino-2-indanol and methyl lactate: on the importance of the CH...pi interaction.

  Physical chemistry chemical physics : PCCP 20090921

• Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan.

  Neurotoxicity research 20090801

• Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.

  Neurotoxicity research 20090401

• Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts.

  Chemical communications (Cambridge, England) 20080521

• Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions.

  Organic letters 20080221

• Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline.

  Journal of neural transmission (Vienna, Austria : 1996) 20080101

• The role of CH/pi interaction in the stabilization of less-soluble diastereomeric salt crystals.

  Chemical record (New York, N.Y.) 20070101

• Fluorescence spectroscopy of jet-cooled chiral (+/-)-indan-1-ol and its cluster with (+/-)-methyl- and ethyl-lactate.

  The Journal of chemical physics 20061107

• cis-1-Amino-2-indanol in drug design and applications to asymmetric processes.

  Chemical reviews 20060701

• Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and omega-transaminase.

  Biotechnology and bioengineering 20060205

• Rational design of CH/pi interaction sites in a basic resolving agent.

  The Journal of organic chemistry 20041029

• Synthetic applicability and in situ recycling of a B-methoxy oxazaborolidine catalyst derived from cis-1-amino-indan-2-ol.

  Organic letters 20040805

• C2-symmetric inhibitors of Plasmodium falciparum plasmepsin II: synthesis and theoretical predictions.

  Bioorganic & medicinal chemistry 20030815

• Improved synthesis of tert-butanesulfinamide suitable for large-scale production.

  Organic letters 20030417

• Measurement of strain-dependent toxicity in the indene bioconversion using multiparameter flow cytometry.

  Biotechnology and bioengineering 20030220

• Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons.

  Applied microbiology and biotechnology 20020801

• Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay.

  Biochemistry 20020122

• Metabolic engineering of indene bioconversion in Rhodococcus sp.

  Advances in biochemical engineering/biotechnology 20010101