74772-78-4 | 5-(4-Hydroxybenzyl)-2,4-thiazolidinedione

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$82.00	$58.00
1g	>95%	in stock	$135.00	$94.00
5g	>95%	in stock	$422.00	$295.00

Description

• Catalog Number: AB68495
• Chemical Name: 5-(4-Hydroxybenzyl)-2,4-thiazolidinedione
• CAS Number: 74772-78-4
• Molecular Formula: C10H9NO3S
• Molecular Weight: 223.2484
• MDL Number: MFCD00754499
• SMILES: O=C1NC(=O)SC1Cc1ccc(cc1)O

Computed Properties

• Complexity: 274
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: 1.7

Literature

• Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity.

  Journal of medicinal chemistry 20121011

• A novel binding assay identifies high affinity ligands to the rosiglitazone binding site of mitoNEET.

  Bioorganic & medicinal chemistry letters 20110915

• Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B.

  Bioorganic & medicinal chemistry letters 20110815

• Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.

  Bioorganic & medicinal chemistry letters 20040517