7517-19-3 | L-Leucine methyl ester, HCl

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$5.00
25g	98%	in stock	$9.00	$6.00
100g	98%	in stock	$18.00	$12.00
500g	98%	in stock	$85.00	$59.00
1000g	98%	in stock	$168.00	$117.00

Description

• Catalog Number: AB75211
• Chemical Name: L-Leucine methyl ester, HCl
• CAS Number: 7517-19-3
• Molecular Formula: C7H16ClNO2
• Molecular Weight: 181.6604
• MDL Number: MFCD00012494
• SMILES: COC(=O)[C@H](CC(C)C)N.Cl

Computed Properties

• Complexity: 112
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Literature

• Generation of primary astrocyte cultures devoid of contaminating microglia.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Conglomerate crystallization on self-assembled monolayers.

  Chemical communications (Cambridge, England) 20111128

• Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

  Nature chemical biology 20090101

• Tumour-associated macrophages secrete IL-6 and MCP-1 in head and neck squamous cell carcinoma tissue.

  Acta oto-laryngologica 20070501

• Effect of L-leucine methyl ester on growth and ultrastructure of Trypanosoma cruzi.

  Acta tropica 20070101

• Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes.

  Journal of neuroscience methods 20060115

• Substrate induction of osteogenesis from marrow-derived mesenchymal precursors.

  Stem cells and development 20051201

• Monocytes stimulated by 110-kDa fibronectin fragments suppress proliferation of anti-CD3-activated T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20050901

• Leishmania amazonensis Rab7 promotes toxicity of the amino acid ester Leu-OMe in amastigote megasomes.

  Molecular and biochemical parasitology 20031201

• L-leucine methyl ester: the female-produced sex pheromone of the scarab beetle, Phyllophaga lanceolata.

  Journal of chemical ecology 20031101

• Leucine methyl ester is a powerful allosteric activator of the neutral amino acid cotransport system in Bombyx mori larval midgut.

  Insect biochemistry and molecular biology 20020701

• Role of specific activators of intestinal amino acid transport in Bombyx mori larval growth and nutrition.

  Archives of insect biochemistry and physiology 20011201

• Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.

  Biochemistry 20010626

• Kinetics of the intracellular differentiation of Leishmania amazonensis and internalization of host MHC molecules by the intermediate parasite stages.

  Parasitology 20010301

• The effect of amino acids and amino acid derivatives on cell proliferation.

  Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma 19930101