75187-63-2 | 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$28.00	$19.00
1g	97%	in stock	$33.00	$23.00
5g	97%	in stock	$80.00	$56.00

Description

• Catalog Number: AC50952
• Chemical Name: 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one
• CAS Number: 75187-63-2
• Molecular Formula: C15H10O5
• Molecular Weight: 270.2369
• MDL Number: MFCD00885567
• SMILES: Oc1ccc(cc1)c1coc2c(c1=O)ccc(c2O)O
• NSC Number: 678112

Computed Properties

• Complexity: 411
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 2.1

Literature

• Synthesis and biological studies of 4', 7, 8-trihydroxy-isoflavone metal complexes.

  Journal of inorganic biochemistry 20111201

• UHPLC method for the simultaneous determination of β-blockers, isoflavones and their metabolites in human urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110315

• Evaluation of in vitro and in vivo depigmenting activity of raspberry ketone from Rheum officinale.

  International journal of molecular sciences 20110101

• Study on the stability of deoxyArbutin in an anhydrous emulsion system.

  International journal of molecular sciences 20110101

• Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells.

  International journal of molecular sciences 20110101

• Chemometric modeling of free radical scavenging activity of flavone derivatives.

  European journal of medicinal chemistry 20101101

• Isoflavone derivatives inhibit NF-κB-dependent transcriptional activity.

  Bioorganic & medicinal chemistry letters 20101101

• Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.

  Bioorganic & medicinal chemistry letters 20100201

• Identifying 8-hydroxynaringenin as a suicide substrate of mushroom tyrosinase.

  Journal of cosmetic science 20100101

• Determination of the thermodegradation of deoxyArbutin in aqueous solution by high performance liquid chromatography.

  International journal of molecular sciences 20100101

• A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152.

  Biotechnology journal 20091101

• Evaluation of depigmenting activity by 8-hydroxydaidzein in mouse B16 melanoma cells and human volunteers.

  International journal of molecular sciences 20091001

• Isolation of a new metabolite from biotransformation of daidzein by Aspergillus oryzae.

  Bioscience, biotechnology, and biochemistry 20090801

• Antiplasmodial isoflavanones from the roots of Sophora mollis.

  Journal of natural products 20090701

• An updated review of tyrosinase inhibitors.

  International journal of molecular sciences 20090601

• 8-Hydroxydaidzein is unstable in alkaline solutions.

  Journal of cosmetic science 20090101

• ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity.

  Bioorganic & medicinal chemistry letters 20080915

• Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease.

  Bioorganic & medicinal chemistry 20070601

• Metabolism of the soy isoflavones daidzein and genistein by fungi used in the preparation of various fermented soybean foods.

  Bioscience, biotechnology, and biochemistry 20070501

• Two potent suicide substrates of mushroom tyrosinase: 7,8,4'-trihydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavone.

  Journal of agricultural and food chemistry 20070307

• Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro.

  The Prostate 20060401

• Absorption and excretion of the 8-hydroxydaidzein in rats after oral administration and its antioxidant effect.

  Journal of nutritional science and vitaminology 20050401

• Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assay.

  The British journal of nutrition 20050301

• [Mechanism of mono-hydroxylation of daidzein in human liver microsomes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20041101

• 8-Hydroxydaidzein, an aldose reductase inhibitor from okara fermented with Aspergillus sp. HK-388.

  Bioscience, biotechnology, and biochemistry 20040701

• Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.

  Bioscience, biotechnology, and biochemistry 20040601

• Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein.

  Free radical research 20040201

• Antioxidant and free radical scavenging activity of isoflavone metabolites.

  Xenobiotica; the fate of foreign compounds in biological systems 20030901

• Evidence for the involvement of human liver microsomes CYP1A2 in the mono-hydroxylation of daidzein.

  Clinica chimica acta; international journal of clinical chemistry 20030801

• Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo.

  Journal of agricultural and food chemistry 20010601