76-84-6 | Triphenylmethanol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$10.00
25g	98%	in stock	$16.00	$11.00
50g	98%	in stock	$18.00	$12.00
100g	98%	in stock	$20.00	$14.00
250g	98%	in stock	$28.00	$19.00
500g	98%	in stock	$36.00	$25.00

Description

• Catalog Number: AB47246
• Chemical Name: Triphenylmethanol
• CAS Number: 76-84-6
• Molecular Formula: C19H16O
• Molecular Weight: 260.3297
• MDL Number: MFCD00004445
• SMILES: OC(c1ccccc1)(c1ccccc1)c1ccccc1
• NSC Number: 4050

Computed Properties

• Complexity: 235
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.7

Upstream Synthesis Route

Triphenylmethanol, a versatile compound used in a wide range of chemical applications, plays a crucial role in organic synthesis processes. This compound is commonly utilized as a key building block in the creation of various organic molecules due to its unique structural properties. In particular, Triphenylmethanol is frequently employed as a reactant in the formation of esters, ethers, and other functionalized compounds through various chemical transformations including esterification and Grignard reactions. Its ability to serve as a potent nucleophile allows for the formation of complex molecular structures with high selectivity and efficiency. This compound is also known for its role as a protecting group in organic synthesis, safeguarding specific functional groups during synthetic manipulations and facilitating the sequential construction of intricate molecules. Moreover, Triphenylmethanol has found applications in the pharmaceutical industry, where it is utilized in the synthesis of key intermediates for drug development. Its versatility and reactivity make it an indispensable tool in the arsenal of synthetic chemists seeking to access diverse chemical compounds with precision and control.

Literature

• Azobenzene-tethered bis(trityl alcohol) as a photoswitchable cooperative acid catalyst for Morita-Baylis-Hillman reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120827

• Trimeth-yl(triphenyl-meth-oxy)silane.

  Acta crystallographica. Section E, Structure reports online 20120201

• Triarylmethanes, a new class of cx50 inhibitors.

  Frontiers in pharmacology 20120101

• Solubilization of triphenylamine, triphenylphosphine, triphenylphosphineoxide and triphenylmethanol in single and binary surfactant systems.

  Journal of colloid and interface science 20111201

• Cyclopropylamines from N,N-dialkylcarboxamides and Grignard reagents in the presence of titanium tetraisopropoxide or methyltitanium triisopropoxide.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20101210

• The rearrangement of the trityloxy radical: Sherlock Holmes' most recent case.

  Angewandte Chemie (International ed. in English) 20100917

• Isomerization of triphenylmethoxyl: the Wieland free-radical rearrangement revisited a century later.

  Angewandte Chemie (International ed. in English) 20100809

• Enantioselective, iridium-catalyzed monoallylation of ammonia.

  Journal of the American Chemical Society 20090819

• Direct synthesis of a photoactive inorganic-organic mesostructured hybrid material and its application as a photocatalyst.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090511

• Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

  Journal of medicinal chemistry 20080313

• NMR studies of coupled low- and high-barrier hydrogen bonds in pyridoxal-5'-phosphate model systems in polar solution.

  Journal of the American Chemical Society 20070516

• N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.

  Journal of medicinal chemistry 20061228

• Isomerization of triphenylmethoxyl and 1,1-diphenylethoxyl radicals. Revised assignment of the electron-spin resonance spectra of purported intermediates formed during the ceric ammonium nitrate mediated photooxidation of aryl carbinols.

  The Journal of organic chemistry 20061222

• Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.

  Journal of medicinal chemistry 20060713

• Hydrocarbon species mu3-CCH2-, mu3-CCH3 and mu-CHCH3 supported on Ti3O3.

  Chemical communications (Cambridge, England) 20050807

• Aluminium alkyl complexes supported by [OSSO] type bisphenolato ligands: synthesis, characterization and living polymerization of rac-lactide.

  Dalton transactions (Cambridge, England : 2003) 20050221

• Electron impact ionization in helium nanodroplets: controlling fragmentation by active cooling of molecular ions.

  Journal of the American Chemical Society 20040915

• Photoaddition of water and alcohols to the anthracene moiety of 9-(2'-hydroxyphenyl)anthracene via formal excited state intramolecular proton transfer.

  Journal of the American Chemical Society 20040630

• Efficient asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl-alpha-methylcysteine using camphorsultam as a chiral auxiliary.

  The Journal of organic chemistry 20040625

• Triaryl methane derivatives as antiproliferative agents.

  Bioorganic & medicinal chemistry letters 20040119

• Improving the selectivity of acyclic nucleoside analogues as inhibitors of human mitochondrial thymidine kinase: replacement of a triphenylmethoxy moiety with substituted amines and carboxamides.

  Bioorganic & medicinal chemistry letters 20030915

• An efficient and large-scale enantioselective synthesis of PNP405: a purine nucleoside phosphorylase inhibitor.

  The Journal of organic chemistry 20020920

• Intermolecular interactions in (arene)chromium carbonyl compounds: prediction of chiral crystal packing from racemate structure.

  Journal of the American Chemical Society 20020508