76045-71-1 | 3-Amino-5-hydroxybenzoic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$24.00	$17.00
5g	97%	in stock	$62.00	$44.00
10g	97%	in stock	$120.00	$84.00

Description

• Catalog Number: AB64266
• Chemical Name: 3-Amino-5-hydroxybenzoic acid
• CAS Number: 76045-71-1
• Molecular Formula: C7H7NO3
• Molecular Weight: 153.1354
• MDL Number: MFCD06797571
• SMILES: Nc1cc(O)cc(c1)C(=O)O

Computed Properties

• Complexity: 160
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 0.5

Literature

• Biosynthesis of 3,5-AHBA-derived natural products.

  Natural product reports 20120201

• Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin.

  Journal of the American Chemical Society 20120125

• Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.

  Molecular bioSystems 20110801

• Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.

  Journal of natural products 20110624

• Mutational biosynthesis of ansamitocin antibiotics: a diversity-oriented approach to exploit biosynthetic flexibility.

  Chembiochem : a European journal of chemical biology 20110307

• The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review.

  The Journal of antibiotics 20110101

• Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.

  Applied microbiology and biotechnology 20101201

• New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis.

  Chembiochem : a European journal of chemical biology 20090720

• Antitumor compounds from marine actinomycetes.

  Marine drugs 20090601

• Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C.

  Organic letters 20090219

• Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system.

  Journal of natural products 20080901

• Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant.

  Chembiochem : a European journal of chemical biology 20080505

• Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061.

  Archives of microbiology 20080501

• Hydroxyquinone O-methylation in mitomycin biosynthesis.

  Journal of the American Chemical Society 20070523

• Biosynthesis of tetrapetalones.

  Organic & biomolecular chemistry 20070521

• An integrative expression vector for Actinosynnema pretiosum.

  BMC biotechnology 20070101

• Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum.

  Chembiochem : a European journal of chemical biology 20060801

• Production of ansamycin polyketide precursors in Escherichia coli.

  The Journal of antibiotics 20060801

• Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis.

  Journal of the American Chemical Society 20050817

• Transformation of the antibacterial agent sulfamethoxazole in reactions with chlorine: kinetics, mechanisms, and pathways.

  Environmental science & technology 20041101

• Kanosamine biosynthesis: a likely source of the aminoshikimate pathway's nitrogen atom.

  Journal of the American Chemical Society 20020911

• Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.

  Journal of the American Chemical Society 20020911

• The loading and initial elongation modules of rifamycin synthetase collaborate to produce mixed aryl ketide products.

  Biochemistry 20020423

• Biosynthesis of 1-deoxy-1-imino-D-erythrose 4-phosphate: a defining metabolite in the aminoshikimate pathway.

  Journal of the American Chemical Society 20020130

• The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates.

  Biochemistry 20010522

• Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.

  The Journal of biological chemistry 20010420