768-35-4 | 3-Fluorophenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$5.00
10g	98%	in stock	$9.00	$6.00
25g	98%	in stock	$12.00	$8.00
100g	98%	in stock	$43.00	$30.00
500g	98%	in stock	$213.00	$149.00

Description

• Catalog Number: AB44581
• Chemical Name: 3-Fluorophenylboronic acid
• CAS Number: 768-35-4
• Molecular Formula: C6H6BFO2
• Molecular Weight: 139.9200
• MDL Number: MFCD00236042
• SMILES: Fc1cccc(c1)B(O)O

Computed Properties

• Complexity: 110
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

3-Fluorophenylboronic Acid is a versatile chemical compound widely used in organic synthesis for its unique reactivity and properties. In chemical synthesis, this compound serves as a vital building block for the construction of a variety of complex molecules. Its fluoro-substituted phenylboronic acid moiety introduces a specific functional group that can enable selective reactions and modifications in target molecules. This compound is particularly prized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, where it can be employed to form carbon-carbon bonds with aryl halides or pseudohalides, enabling the creation of diverse biaryl compounds and other valuable structures. Additionally, 3-Fluorophenylboronic Acid can be utilized in the synthesis of pharmaceuticals, agrochemicals, and materials with enhanced properties due to the presence of the fluorine substituent. Its strategic incorporation into molecular design strategies allows for the synthesis of novel compounds with tailored functionalities and improved performance characteristics in various applications.

Literature

• Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.

  ChemMedChem 20120102

• Synthesis of boroxine-linked aluminum complexes.

  Inorganic chemistry 20110307

• Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.

  Molecular microbiology 20091101

• 2,4-Difluoro-phenyl-boronic acid.

  Acta crystallographica. Section E, Structure reports online 20090101

• A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides.

  Beilstein journal of organic chemistry 20070101