7681-57-4 | Sodium metabisulfite

Packsize	Purity	Availability	Price	Discounted Price
25g	97%	in stock	$12.00	$9.00
100g	97%	in stock	$22.00	$16.00
500g	97%	in stock	$35.00	$24.00
5kg	97%	in stock	$172.00	$120.00
10kg	97%	in stock	$252.00	$176.00
25kg	97%	in stock	$500.00	$350.00
100kg	97%	in stock	$1,713.00	$1,200.00

Description

• Catalog Number: AB47030
• Chemical Name: Sodium metabisulfite
• CAS Number: 7681-57-4
• Molecular Formula: Na2O5S2
• Molecular Weight: 190.1065
• MDL Number: MFCD00167602
• SMILES: [O-]S(=O)S(=O)(=O)[O-].[Na+].[Na+]

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 6

Upstream Synthesis Route

Sodium metabisulfite, also known as sodium pyrosulfite, is a versatile chemical compound widely used in various chemical synthesis processes. In chemical synthesis, sodium metabisulfite plays a crucial role as a reducing agent. Its ability to release sulfur dioxide gas makes it valuable for deoxygenating and dechlorinating reactions. This compound is commonly utilized in organic chemistry for the reduction of carbonyl compounds and oxidative degradation of organic materials. Additionally, sodium metabisulfite is employed in the synthesis of pharmaceuticals, dyes, and antioxidants. Its effectiveness as a mild reducing agent makes it a valuable tool in the production of a wide range of chemical compounds.

Literature

• SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study.

  Toxicology in vitro : an international journal published in association with BIBRA 20160401

• Occupational allergic contact dermatitis and patch test results of leather workers at two Indonesian tanneries.

  Contact dermatitis 20121101

• Formation of reactive impurities in aqueous and neat polyethylene glycol 400 and effects of antioxidants and oxidation inducers.

  Journal of pharmaceutical sciences 20120901

• The vasodilator mechanisms of sodium metabisulfite on precontracted isolated aortic rings in rats: signal transduction pathways and ion channels.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

• The effect of sodium metabisulphite on active avoidance performance in hypercholesterolemic rats.

  Environmental toxicology 20120801

• New saccharin derivatives as tyrosinase inhibitors.

  Bioorganic & medicinal chemistry 20120501

• A mathematical model for calculating the shelf life of ascorbic acid solution under given conditions.

  Drug development and industrial pharmacy 20120301

• Sodium metabisulfite as a contact allergen--an example of a rare chemical mechanism for protein modification.

  Contact dermatitis 20120301

• Development of surface coating material for discolored tooth equipped with bleaching effect.

  Dental materials journal 20120101

• Hippocampal neuron number loss in rats exposed to ingested sulfite.

  Toxicology and industrial health 20111001

• Effect of various anticoagulant agents on large-volume leukocytapheresis using new Cellsorba CS-180S Filter.

  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20110801

• The effect of sodium metabisulfite on visual evoked potentials in rats with hypercholesterolemia.

  Toxicology mechanisms and methods 20110701

• Injection of air into the headspace improves fermentation of phosphoric acid pretreated sugarcane bagasse by Escherichia coli MM170.

  Bioresource technology 20110701

• Dose-dependent effect of nutritional sulfite intake on visual evoked potentials and lipid peroxidation.

  Neurotoxicology and teratology 20110101

• Purification and partial biochemical characterization of polyphenol oxidase from mamey (Pouteria sapota).

  Phytochemistry 20110101

• New and emerging cosmetic allergens.

  Clinics in dermatology 20110101

• Immediate type 1 hypersensitivity to apomorphine: a case report.

  Journal of investigational allergology & clinical immunology 20110101

• Determination of sodium metabisulfite in parenteral formulations by HPIC with suppressed conductivity detection.

  Acta poloniae pharmaceutica 20110101

• Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20101101

• Approaches to improve the stability of the antiviral agent UC781 in aqueous solutions.

  International journal of pharmaceutics 20100830

• Sodium metabisulfite induces lipid peroxidation and apoptosis in rat gastric tissue.

  Toxicology and industrial health 20100801

• Chondrotoxicity of low pH, epinephrine, and preservatives found in local anesthetics containing epinephrine.

  The American journal of sports medicine 20100601

• Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents.

  Archives of animal nutrition 20100601

• Modelling the effect of ascorbic acid, sodium metabisulphite and sodium chloride on the kinetic responses of lactic acid bacteria and yeasts in table olive storage using a specifically implemented Quasi-chemical primary model.

  International journal of food microbiology 20100415

• Purification and biochemical characterization of polyphenol oxidases from embryogenic and nonembryogenic cotton (Gossypium hirsutum L.) cells.

  Applied biochemistry and biotechnology 20090801

• Purification and characterization of cell suspensions peroxidase from cotton (Gossypium hirsutum L.).

  Applied biochemistry and biotechnology 20090601

• Ultrastructural alterations in Fusarium sambucinum and Heterobasidion annosum treated with aluminum chloride and sodium metabisulfite.

  Phytopathology 20090201

• Bilateral infiltrative orbital disease: is it chemically induced?

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20081001

• Effects of a Fusarium toxin-contaminated triticale, either untreated or treated with sodium metabisulphite (Na2S2O5, SBS), on weaned piglets with a special focus on liver function as determined by the 13C-methacetin breath test.

  Archives of animal nutrition 20080801

• Chlorhexidine with an anti discoloration system after periodontal flap surgery: a cross-over, randomized, triple-blind clinical trial.

  Journal of clinical periodontology 20080701

• Effect of preservative agents on the respiration rate of minimally processed potato (Solanum tuberosum cv. Monalisa).

  Journal of food science 20080401

• Toxicity of corticosteroids and catecholamines for mice neuronal cell cultures: Role of preservatives.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20070401

• Effect of formulation factors on in-vitro permeation of diclofenac from experimental and marketed aqueous eye drops through excised goat cornea.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061201

• Influence of sodium metabisulfite and glutathione on the stability of vitamin C in O/W emulsion and extemporaneous aqueous gel.

  International journal of pharmaceutics 20060928

• The effect of sulfite and chronic restraint stress on brain lipid peroxidation and anti-oxidant enzyme activities.

  Toxicology and industrial health 20060701

• A reassessment of semiquantitative analytical procedures for DNA methylation: comparison of bisulfite- and HpaII polymerase-chain-reaction-based methods.

  Analytical biochemistry 20060301

• Solubilization and quantification of lycopene in aqueous media in the form of cyclodextrin binary systems.

  International journal of pharmaceutics 20060217

• Visual evoked potentials in normal and sulfite oxidase deficient rats exposed to ingested sulfite.

  Neurotoxicology 20060101

• DNA methylation: bisulphite modification and analysis.

  Nature protocols 20060101

• The effect of chronic restraint stress and sulfite on visual evoked potentials (VEPs): relation to lipid peroxidation.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050701

• The prooxidant effect of sodium metabisulfite in rat liver and kidney.

  Regulatory toxicology and pharmacology : RTP 20050601

• Purification and characterization of polyphenol oxidase from nettle (Urtica dioica L.) and inhibitory effects of some chemicals on enzyme activity.

  Journal of enzyme inhibition and medicinal chemistry 20050601

• Effects of sodium metabisulfite on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050201

• Metabisulphite-induced occupational asthma in a radiographer.

  The European respiratory journal 20050201

• Type IV hypersensitivity to sodium metabisulfite in local anaesthetic.

  Contact dermatitis 20040901

• Chlorhexidine with an Anti Discoloration System. A comparative study.

  International journal of dental hygiene 20040801

• Fat-globule size in a propofol emulsion containing sodium metabisulfite.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040615

• A dilemma: How does one treat anaphylaxis in the sulfite allergic patient since epinephrine contains sodium metabisulfite?

  Anesthesia and analgesia 20040501

• Monosodium benzoate hypersensitivity in subjects with persistent rhinitis.

  Allergy 20040201

• A mechanism of airway injury in an epithelial model of mucociliary clearance.

  Respiratory research 20040101

• Inactivation of Salmonella during drying and storage of apple slices treated with acidic or sodium metabisulfite solutions.

  Journal of food protection 20031201

• Growth of microorganisms in propofol and methohexital mixtures.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20030701

• Sulfite-induced propofol oxidation: a cause for radical concern.

  Critical care medicine 20030301

• Comparison of antioxidant activity of extract from roots of licorice (Glycyrrhiza glabra L.) to commercial antioxidants in 2% hydroquinone cream.

  Journal of cosmetic science 20030101

• Urinary metabolites of histamine and leukotrienes before and after placebo-controlled challenge with ASA and food additives in chronic urticaria patients.

  Allergy 20021201

• Sulfite supported lipid peroxidation in propofol emulsions.

  Anesthesiology 20021101

• Effect of endogenous triacylglycerol hydrolysates on the mechanical properties of Zein films from ground corn.

  Journal of agricultural and food chemistry 20020522

• Concomitant sensitivity to sodium metabisulfite and clobetasone butyrate in Trimovate cream.

  Contact dermatitis 20020501

• Inhibitors of advanced glycation end product-associated protein cross-linking.

  Biochimica et biophysica acta 20010214

• Absence of adverse effects of sodium metabisulphite in manufactured biscuits: results of subacute (28-days) and subchronic (85-days) feeding studies in rats.

  Food additives and contaminants 20010201

• Analysis for loss of heterozygosity (LOH) of p53 allele in tumors derived from p53+/- and CD-1 mice following repeated subcutaneous injections of solutions containing antioxidants.

  Environmental and molecular mutagenesis 20010101