7764-95-6 | (R)-2-((tert-Butoxycarbonyl)amino)propanoic acid hydrate

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$8.00	$5.00
10g	97%	in stock	$10.00	$7.00
25g	97%	in stock	$18.00	$13.00
50g	97%	in stock	$29.00	$20.00
100g	97%	in stock	$58.00	$40.00
500g	97%	in stock	$136.00	$95.00

Description

• Catalog Number: AB71457
• Chemical Name: (R)-2-((tert-Butoxycarbonyl)amino)propanoic acid hydrate
• CAS Number: 7764-95-6
• Molecular Formula: C8H15NO4
• Molecular Weight: 189.209
• MDL Number: MFCD26383924
• SMILES: C[C@H](C(=O)O)NC(=O)OC(C)(C)C

Computed Properties

• Complexity: 207
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 0.9

Upstream Synthesis Route

Boc-D-Ala-OH, also known as tert-butoxycarbonyl-D-alanine, is a versatile compound widely used in chemical synthesis, specifically in peptide chemistry. This compound serves as a protecting group for the amino group of D-alanine, allowing for selective manipulation of other functional groups within a peptide chain.By temporarily masking the amino group with the Boc (tert-butoxycarbonyl) protecting group, Boc-D-Ala-OH enables chemists to perform various reactions without interference from the amino group. This protection strategy is crucial in the stepwise assembly of peptides, where multiple amino acids are linked together to form the desired peptide sequence.In peptide synthesis, Boc-D-Ala-OH plays a crucial role in the solid-phase peptide synthesis (SPPS) method. During SPPS, the amino acids are attached to a solid support and activated for coupling reactions. By using Boc-D-Ala-OH as one of the building blocks, chemists can efficiently construct peptide chains with precise control over sequence and functionality.Furthermore, Boc-D-Ala-OH offers chemists the flexibility to deprotect the amino group selectively at a later stage, enabling the continuation of the peptide synthesis process. This reversible protection strategy enhances the overall efficiency and success of peptide synthesis efforts.Overall, the application of Boc-D-Ala-OH in chemical synthesis, particularly in peptide chemistry, provides researchers with a powerful tool for the strategic design and assembly of complex peptide structures.

Literature

• Microspheres consisting of optically active helical substituted polyacetylenes: preparation via suspension polymerization and their chiral recognition/release properties.

  Macromolecular rapid communications 20111215