78755-81-4 | ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$22.00	$15.00
5mg	95%	in stock	$40.00	$28.00
10mg	95%	in stock	$49.00	$34.00
25mg	95%	in stock	$62.00	$43.00
50mg	95%	in stock	$73.00	$51.00
100mg	95%	in stock	$113.00	$79.00
250mg	95%	in stock	$114.00	$80.00
1g	95%	in stock	$283.00	$198.00
5g	95%	in stock	$1,226.00	$858.00

Description

• Catalog Number: AC58245
• Chemical Name: ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate
• CAS Number: 78755-81-4
• Molecular Formula: C15H14FN3O3
• Molecular Weight: 303.28836319999994
• MDL Number: MFCD00242764
• SMILES: CCOC(=O)c1ncn2-c3ccc(cc3C(=O)N(Cc12)C)F
• NSC Number: 759193

Computed Properties

• Complexity: 461
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• XLogP3: 1

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• Lorazepam-induced prolonged apnea after ECT-induced prolonged seizure.

  Indian journal of psychiatry 20110101

• Anxiolytic-like effects of 4-O-methylhonokiol isolated from Magnolia officinalis through enhancement of GABAergic transmission and chloride influx.

  Journal of medicinal food 20110101

• Influence of a brief episode of anesthesia during the induction of experimental brain trauma on secondary brain damage and inflammation.

  PloS one 20110101

• Is attentional blink a byproduct of neocortical attractors?

  Frontiers in computational neuroscience 20110101

• Management of an oral ingestion of transdermal fentanyl patches: a case report and literature review.

  Case reports in medicine 20110101

• Drug interaction leading to prolonged sedation in a postoperative high risk coronary bypass surgery patient.

  Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20110101

• Aerosolized BC-819 inhibits primary but not secondary lung cancer growth.

  PloS one 20110101

• Midazolam activates the intrinsic pathway of apoptosis independent of benzodiazepine and death receptor signaling.

  Regional anesthesia and pain medicine 20110101

• Securinine, a myeloid differentiation agent with therapeutic potential for AML.

  PloS one 20110101

• α4-Containing GABA(A) Receptors are Required for Antagonism of Ethanol-Induced Motor Incoordination and Hypnosis by the Imidazobenzodiazepine Ro15-4513.

  Frontiers in pharmacology 20110101

• Water chreodes and the mechanisms of ligand diffusion, general anesthesia, and sleep.

  Biochemistry research international 20110101

• GABA(A) Receptor β3 Subunit Expression Regulates Tonic Current in Developing Striatopallidal Medium Spiny Neurons.

  Frontiers in cellular neuroscience 20110101

• Yokukansan enhances pentobarbital-induced sleep in socially isolated mice: possible involvement of GABA(A)-benzodiazepine receptor complex.

  Journal of pharmacological sciences 20110101

• Central Nervous System Effects of Iso-6-spectaline Isolated from Senna Spectabilis var. Excelsa (Schrad) in Mice.

  Journal of young pharmacists : JYP 20110101

• Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.

  PloS one 20110101

• The ischemic penumbra: correlates in imaging and implications for treatment of ischemic stroke. The Johann Jacob Wepfer award 2011.

  Cerebrovascular diseases (Basel, Switzerland) 20110101

• Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice.

  Particle and fibre toxicology 20110101

• Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets.

  Particle and fibre toxicology 20110101

• Prescribing medications in patients with decompensated liver cirrhosis.

  International journal of hepatology 20110101

• Management of hepatic encephalopathy.

  International journal of hepatology 20110101

• Inverse agonism and its therapeutic significance.

  Indian journal of pharmacology 20110101

• Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model.

  Advances in pharmacological sciences 20110101

• Subcutaneous dissociative conscious sedation (sDCS) an alternative method for airway regional blocks: a new approach.

  BMC anesthesiology 20110101

• Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence.

  Advances in pharmacological sciences 20110101

• Drugs for pain management in shock wave lithotripsy.

  Pain research and treatment 20110101

• Procedural sedation: A review of sedative agents, monitoring, and management of complications.

  Saudi journal of anaesthesia 20110101

• Neuropharmacological profile of aqueous extract of Anaphe venata larva (Notondotidae) in rats.

  African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101

• Neurosteroids and GABA-A Receptor Function.

  Frontiers in endocrinology 20110101

• The use of flumazenil after midazolam-induced conscious sedation.

  British dental journal 20101211

• Summary of: the use of flumazenil after midazolam-induced conscious sedation.

  British dental journal 20101211

• Remarkable selectivity of the in vivo binding of [3H]Ro15-4513 to α5 subtype of benzodiazepine receptor in the living mouse brain.

  Synapse (New York, N.Y.) 20101201

• Emerging drugs to treat alcoholism.

  Expert opinion on emerging drugs 20101201

• Occupancy of human brain GABA(A) receptors by the novel α5 subtype-selective benzodiazepine site inverse agonist α5IA as measured using [¹¹C]flumazenil PET imaging.

  Neuropharmacology 20101201

• Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems.

  Neuropharmacology 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Diazepam decreases action potential firing of neocortical neurons via two distinct mechanisms.

  Anesthesia and analgesia 20101201

• Paradoxical reaction following administration of a benzodiazepine.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20101201

• Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: evaluation using ¹¹C-flumazenil positron emission tomography with statistical image analysis.

  Journal of neurotrauma 20101201

• [Plasma concentration of propofol was 4.4 microg x ml(-1), 4.5 hours after completion of its administration].

  Masui. The Japanese journal of anesthesiology 20101201

• Ventricular tachycardia due to flumazenil administration.

  Pakistan journal of biological sciences : PJBS 20101201

• Anaphe venata larva extract-induced purposeless chewing in rats: the role of cholinergic, GABAergic and opioid systems.

  Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20101125

• New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on γ-aminobutyrric acid type A (GABA(A)) receptor. Design, synthesis, biological, and molecular modeling investigation.

  Journal of medicinal chemistry 20101111

• Flumazenil expedites recovery from sevoflurane/remifentanil anaesthesia when administered to healthy unpremedicated patients.

  European journal of anaesthesiology 20101101

• Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.

  Bioorganic & medicinal chemistry 20101101

• Evaluation of butorphanol, medetomidine and midazolam as a reversible narcotic combination in free-ranging African lions (Panthera leo).

  Veterinary anaesthesia and analgesia 20101101

• Neurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathway.

  Neuroscience 20101027

• Mismatch between changes in baicalein-induced memory-related biochemical parameters and behavioral consequences in mouse.

  Brain research 20101008

• Dimensions of a projection column and architecture of VPM and POm axons in rat vibrissal cortex.

  Cerebral cortex (New York, N.Y. : 1991) 20101001

• Recovered neuronal viability revealed by Iodine-123-iomazenil SPECT following traumatic brain injury.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101001

• Reversible dysfunction of receptors in traumatic brain injury?

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101001

• Effects of benzodiazepine treatment on cortical GABA(A) and muscarinic receptors: studies in schizophrenia and rats.

  Psychiatry research 20100930

• Current and emerging strategies for treating hepatic encephalopathy.

  Critical care nursing clinics of North America 20100901

• Role of colonoscopy in the diagnosis and treatment of pediatric lower gastrointestinal disorders.

  Korean journal of pediatrics 20100901

• A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation.

  Current neuropharmacology 20100901

• Anxiolytic-like effect of Carvacrol (5-isopropyl-2-methylphenol) in mice: involvement with GABAergic transmission.

  Fundamental & clinical pharmacology 20100801

• Reduction of aggression during benzodiazepine withdrawal: effects of flumazenil.

  Pharmacology, biochemistry, and behavior 20100801

• A case of frontal lobe epilepsy in which amplitude-integrated EEG combined with conventional EEG was useful for evaluating clusters of seizures.

  Epilepsy & behavior : E&B 20100801

• Zolpidem poisoning in a cat.

  Australian veterinary journal 20100801

• The concept of the penumbra: can it be translated to stroke management?

  International journal of stroke : official journal of the International Stroke Society 20100801

• Multimodal neuroimaging in presurgical evaluation of childhood epilepsy.

  Korean journal of pediatrics 20100801

• Sedative and anticonvulsant activities of methanol extract of Dorstenia arifolia in mice.

  Journal of ethnopharmacology 20100706

• Defective cerebral gamma-aminobutyric acid-A receptor density in patients with systemic lupus erythematosus and central nervous system involvement. An observational study.

  Lupus 20100701

• GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100701

• [Case report: a 65-year-old man loses consciousness after colonoscopy].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20100701

• Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding.

  Neuroscience letters 20100621

• Diagnosis of brain death.

  Neurology international 20100621

• Reversible hepatic decerebration: a case report and review of the literature.

  European journal of gastroenterology & hepatology 20100601

• Prospective comparative assessment of buprenorphine overdose with heroin and methadone: clinical characteristics and response to antidotal treatment.

  Journal of substance abuse treatment 20100601

• Zolpidem modulation of phasic and tonic GABA currents in the rat dorsal motor nucleus of the vagus.

  Neuropharmacology 20100601

• SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment.

  European journal of nuclear medicine and molecular imaging 20100601

• Pharmacotherapy of hepatic encephalopathy in cirrhosis.

  Expert opinion on pharmacotherapy 20100601

• Extending submarine crew survival by reducing CO2 production with quickly reversible sedation.

  Aviation, space, and environmental medicine 20100601

• The routine use of a flumazenil infusion following percutaneous endoscopic gastrostomy placement to reduce early post-procedure mortality.

  The journal of the Royal College of Physicians of Edinburgh 20100601

• Antinociceptive effect of Heliopsis longipes extract and affinin in mice.

  Planta medica 20100501

• GABA(A) receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone.

  Biochemical pharmacology 20100501

• In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model.

  European journal of nuclear medicine and molecular imaging 20100501

• Pharmacological characterization of the discriminative stimulus of inhaled 1,1,1-trichloroethane.

  The Journal of pharmacology and experimental therapeutics 20100501

• Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal area.

  Epilepsy research 20100501

• Comparative anticonvulsant activities of the essential oils (EOs) from Cymbopogon winterianus Jowitt and Cymbopogon citratus (DC) Stapf. in mice.

  Naunyn-Schmiedeberg's archives of pharmacology 20100501

• Molecular basis and current treatment for alcoholic liver disease.

  International journal of environmental research and public health 20100501

• Ecophysiology of neuronal metabolism in transiently oxygen-depleted environments: evidence that GABA is accumulated pre-synaptically in the cerebellum.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20100401

• Evaluation of the analgesic effect of aqueous extract of Brugmansia suaveolens flower in mice: possible mechanism involved.

  Biological research for nursing 20100401

• Availability of antidotes for the treatment of acute poisoning in Queensland public hospitals.

  The Australian journal of rural health 20100401

• Evaluation of behavioral and pharmacological effects of Hedyosmum brasiliense and isolated sesquiterpene lactones in rodents.

  Journal of ethnopharmacology 20100302

• Reduced parahippocampal and lateral temporal GABAA-[11C]flumazenil binding in major depression: preliminary results.

  European journal of nuclear medicine and molecular imaging 20100301

• Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact.

  Journal of neurotrauma 20100301

• Colonoscopy and sedation in Romania: early experience using a balanced propofol regimen.

  Journal of gastrointestinal and liver diseases : JGLD 20100301

• HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site.

  Journal of natural products 20100226

• In vivo validation of reconstruction-based resolution recovery for human brain studies.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100201

• Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): role of GABA(A) receptor subtypes.

  Neuropharmacology 20100201

• The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis.

  Toxicology letters 20100201

• Spontaneous recovery of reduced cortical central benzodiazepine receptor binding potential on I-123 Iomazenil SPECT in a patient with status epilepticus.

  Clinical nuclear medicine 20100201

• [Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].

  Revista espanola de anestesiologia y reanimacion 20100201

• The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.

  Neuroscience letters 20100122

• Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans.

  The Journal of pharmacology and experimental therapeutics 20100101

• Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at alpha1 and alpha2/3 subtypes.

  The Journal of pharmacology and experimental therapeutics 20100101

• Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations: comment.

  Paediatric anaesthesia 20100101

• Interesting image. I-123 iomazenil SPECT imaging in a patient with hemispheric brain damage due to cerebral ischemia during carotid endarterectomy.

  Clinical nuclear medicine 20100101

• Combined sedation with midazolam/propofol for gastrointestinal endoscopy in elderly patients.

  BMC gastroenterology 20100101

• [Drugs and the mechanism for reversing the tolerance of flurazepan in rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100101

• Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex: a SPECT study.

  Cerebrovascular diseases (Basel, Switzerland) 20100101

• Sedation at sea of entangled North Atlantic right whales (Eubalaena glacialis) to enhance disentanglement.

  PloS one 20100101

• Drugs and pharmaceuticals: management of intoxication and antidotes.

  EXS 20100101

• Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice.

  Neuropharmacology 20100101

• Pharmacology of sedation agents and reversal agents.

  Digestion 20100101

• Ability to reverse deeper levels of unintended sedation.

  Digestion 20100101

• Epilepsy: The future scenario.

  Annals of Indian Academy of Neurology 20100101

• Sedation and anesthesia options for pediatric patients in the radiation oncology suite.

  International journal of pediatrics 20100101

• Glasgow Coma Scale in acute poisonings before and after use of antidote in patients with history of use of psychotropic agents.

  Srpski arhiv za celokupno lekarstvo 20100101

• Continuous cervical epidural analgesia for Isshiki type - I thyroplasty.

  Indian journal of anaesthesia 20100101

• Impact of sleep and its disturbances on hypothalamo-pituitary-adrenal axis activity.

  International journal of endocrinology 20100101

• Procedural sedation analgesia.

  Saudi journal of anaesthesia 20100101

• Epilepsy surgery: recommendations for India.

  Annals of Indian Academy of Neurology 20100101

• Distinct α subunit variations of the hypothalamic GABAA receptor triplets (αβγ) are linked to hibernating state in hamsters.

  BMC neuroscience 20100101

• Local erythropoietin and endothelial progenitor cells improve regional cardiac function in acute myocardial infarction.

  BMC cardiovascular disorders 20100101

• Paradoxical reaction to midazolam reversed with flumazenil.

  Journal of emergencies, trauma, and shock 20100101

• Pharmacological intervention: Reversal of sedation.

  Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20100101

• Kleine-Levin syndrome: Etiology, diagnosis, and treatment.

  Annals of Indian Academy of Neurology 20100101

• Inadvertent injection of piperacillin - tazobactum into epidural space.

  Journal of anaesthesiology, clinical pharmacology 20100101

• Effect of soybean supplementation on the memory of alprazolam-induced amnesic mice.

  Journal of pharmacy & bioallied sciences 20100101

• Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview.

  Pharmacognosy reviews 20100101

• Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity.

  Fitoterapia 20091201

• GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression.

  Synapse (New York, N.Y.) 20091201

• Cardiovascular responses to intravenous injection of a novel isoindolin-1-one derivate in conscious rats.

  Brain research 20091201

• Hemodynamic compromise as a cause of internal border-zone infarction and cortical neuronal damage in atherosclerotic middle cerebral artery disease.

  Stroke 20091201

• Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors.

  Journal of neurochemistry 20091201

• Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat.

  AANA journal 20091201

• Involvement of the benzodiazepine system in the anxiolytic-like effect of Yokukansan (Yi-gan san).

  Progress in neuro-psychopharmacology & biological psychiatry 20091113

• In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist.

  The Journal of pharmacology and experimental therapeutics 20091101

• Safety of transesophageal echocardiography in adults: study in a multidisciplinary hospital.

  Arquivos brasileiros de cardiologia 20091101

• Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091001

• Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.

  The Journal of pharmacology and experimental therapeutics 20091001

• Improved work-up procedure for the production of [(18)F]flumazenil and first results of its use with a high-resolution research tomograph in human stroke.

  Nuclear medicine and biology 20091001

• What has positron emission tomography told us about the epileptogenic zone?

  Revue neurologique 20091001

• Summary of the american college for advancement in medicine november 2007 conference on integrative medicine: advancing science and clinical practice.

  Evidence-based complementary and alternative medicine : eCAM 20090901

• Lamina-specific changes in hippocampal GABA(A)/cBZR and mossy fibre sprouting during and following amygdala kindling in the rat.

  Neurobiology of disease 20090901

• Rifampicin treatment of persistently elevated benzodiazepine metabolites in a comatose patient.

  Intensive care medicine 20090901

• The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems.

  Neuropharmacology 20090901

• Neonatal phencyclidine treatment in mice induces behavioral, histological and neurochemical abnormalities in adulthood.

  Biological & pharmaceutical bulletin 20090901

• Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.

  Journal of medicinal chemistry 20090813

• Decreased GABA-A binding on FMZ-PET in succinic semialdehyde dehydrogenase deficiency.

  Neurology 20090811

• Sedative and hypothermic effects of gamma-hydroxybutyrate (GHB) in rats alone and in combination with other drugs: assessment using biotelemetry.

  Drug and alcohol dependence 20090801

• Population patch-clamp electrophysiology analysis of recombinant GABAA alpha1beta3gamma2 channels expressed in HEK-293 cells.

  Journal of biomolecular screening 20090801

• Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms.

  Journal of clinical psychopharmacology 20090801

• Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations.

  Paediatric anaesthesia 20090801

• Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.

  Fundamental & clinical pharmacology 20090801

• Haloperidol plus promethazine for psychosis-induced aggression.

  The Cochrane database of systematic reviews 20090708

• Signal separation and parameter estimation in noninvasive dual-tracer PET scans using reference-region approaches.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090701

• The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primates.

  British journal of pharmacology 20090701

• Paradoxical reaction to midazolam reversed with flumazenil in a patient undergoing tumescent liposuction.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090701

• Central action of Araucaria angustifolia seed lectin in mice.

  Epilepsy & behavior : E&B 20090701

• The role of flumazenil in the treatment of benzodiazepine dependence: physiological and psychological profiles.

  Journal of psychopharmacology (Oxford, England) 20090601

• In-vivo imaging characteristics of two fluorinated flumazenil radiotracers in the rat.

  European journal of nuclear medicine and molecular imaging 20090601

• Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model.

  Planta medica 20090601

• Impairment of the cortical GABAergic inhibitory system in catatonic stupor: a case report with neuroimaging.

  Epileptic disorders : international epilepsy journal with videotape 20090601

• Panic attack associated with flumazenil at electroconvulsive therapy session.

  The journal of ECT 20090601

• [Seizure triggered by benzodiazepine receptor antagonist].

  Ugeskrift for laeger 20090601

• Midazolam-related drug interactions: detection of risk situations to the patient safety in a brazilian teaching hospital.

  Journal of patient safety 20090601

• Carisoprodol-mediated modulation of GABAA receptors: in vitro and in vivo studies.

  The Journal of pharmacology and experimental therapeutics 20090501

• Effect of flumazenil on bispectral index monitoring in unpremedicated patients.

  Anesthesiology 20090501

• Flumazenil reversal of sublingual triazolam: a randomized controlled clinical trial.

  Journal of the American Dental Association (1939) 20090501

• Development of microwave-based automated nucleophilic [(18)F]fluorination system and its application to the production of [(18)F]flumazenil.

  Nuclear medicine and biology 20090501

• A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs.

  Behavioural pharmacology 20090501

• Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test.

  Brain research 20090424

• [18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil.

  NeuroImage 20090415

• Kinetic modelling of [11C]flumazenil using data-driven methods.

  European journal of nuclear medicine and molecular imaging 20090401

• In vitro antiproliferative characteristics of flavonoids and diazepam on SNU-C4 colorectal adenocarcinoma cells.

  Journal of natural medicines 20090401

• Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice.

  Pharmacology, biochemistry, and behavior 20090401

• The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices.

  Anesthesia and analgesia 20090401

• Kaempferol from the leaves of Apocynum venetum possesses anxiolytic activities in the elevated plus maze test in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401

• Demographics of toxic exposures presenting to three public hospital emergency departments in Singapore 2001-2003.

  International journal of emergency medicine 20090401

• GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus.

  Journal of neurophysiology 20090301

• Sensitization, duration, and pharmacological blockade of anxiety-like behavior following repeated ethanol withdrawal in adolescent and adult rats.

  Alcoholism, clinical and experimental research 20090301

• Pharmacological exploration of the sedative mechanism of hesperidin identified as the active principle of Citrus sinensis flowers.

  Planta medica 20090301

• The antinociceptive effects and pharmacological properties of JM-1232(-): a novel isoindoline derivative.

  Anesthesia and analgesia 20090301

• Reversal of sedation with flumazenil in a child after traumatic brain injury.

  Journal of neurosurgery. Pediatrics 20090301

• [Time limits for gastrointestinal decontamination in poisoning].

  Ugeskrift for laeger 20090223

• Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

• Focal decreases of cortical GABAA receptor binding remote from the primary seizure focus: what do they indicate?

  Epilepsia 20090201

• Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123I-iomazenil SPECT study.

  Stroke 20090201

• Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice.

  Pain 20090201

• Effect of intravenous flumazenil on oral midazolam pharmacokinetics and pharmacodynamics for use as a cytochrome P450 3A probe.

  International journal of clinical pharmacology and therapeutics 20090201

• Investigation of the anxiolytic effects of luteolin, a lemon balm flavonoid in the male Sprague-Dawley rat.

  AANA journal 20090201

• [Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam].

  Vojnosanitetski pregled 20090201

• Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101

• Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography.

  Epilepsia 20090101

• Accuracy of 3-dimensional reconstruction algorithms for the high-resolution research tomograph.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090101

• Midazolam inhibits tumor necrosis factor-alpha-induced endothelial activation: involvement of the peripheral benzodiazepine receptor.

  Anesthesiology 20090101

• In vivo saturation binding of GABA-A receptor ligands to estimate receptor occupancy using liquid chromatography/tandem mass spectrometry.

  Biopharmaceutics & drug disposition 20090101

• Pharmacology of ramelteon, a selective MT1/MT2 receptor agonist: a novel therapeutic drug for sleep disorders.

  CNS neuroscience & therapeutics 20090101

• Review of knee arthroscopy performed under local anesthesia.

  Sports medicine, arthroscopy, rehabilitation, therapy & technology : SMARTT 20090101

• Expression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current.

  Neuropharmacology 20090101

• Management of the critically poisoned patient.

  Scandinavian journal of trauma, resuscitation and emergency medicine 20090101

• Prophylatic treatment of migraine and migraine clinical variants with topiramate: an update.

  Therapeutics and clinical risk management 20090101

• Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation.

  PloS one 20090101

• [Flumazenil restores amnesic trace of memory in mice with depression-like state].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Studying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) Receptors.

  Frontiers in molecular neuroscience 20090101

• A seizure attributed to ofloxacine in a woman undergoing detoxification for alcohol dependence.

  Case reports in medicine 20090101

• The localization of inhibitory neurotransmitter receptors on dopaminergic neurons of the human substantia nigra.

  Journal of neural transmission. Supplementum 20090101

• Image derived input functions for dynamic High Resolution Research Tomograph PET brain studies.

  NeuroImage 20081201

• Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory and neuropathic pain.

  The Journal of pharmacology and experimental therapeutics 20081201

• Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system.

  Planta medica 20081201

• Doctors' knowledge of the appropriate use and route of administration of antidotes in the management of recreational drug toxicity.

  Emergency medicine journal : EMJ 20081201

• A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells.

  Assay and drug development technologies 20081201

• Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different.

  Journal of medicinal chemistry 20081127

• Anticonvulsant activity of Carissa edulis (Vahl) (Apocynaceae) root bark extract.

  Journal of ethnopharmacology 20081120

• 2-Phenyl-imidazo[1,2-a]pyridine compounds containing hydrophilic groups as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity and electrophysiological studies.

  Journal of medicinal chemistry 20081113

• Participation of the GABA/benzodiazepine receptor and the NO-cyclicGMP pathway in the 'antinociceptive-like effects' of diazepam.

  Pharmacology, biochemistry, and behavior 20081101

• Effects of FG7142 and immobilization stress on the gene expression in the neocortex of mice.

  Neuroscience research 20081101

• Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice.

  Hormones and behavior 20081101

• Utility of flumazenil in zopiclone overdose.

  Clinical toxicology (Philadelphia, Pa.) 20081101

• Sleep deprivation therapy.

  Neuro endocrinology letters 20081101

• Reduced midazolam clearance must be considered in prolonged coma.

  Anaesthesia and intensive care 20081101

• Treatment of minimal hepatic encephalopathy.

  Hepatology research : the official journal of the Japan Society of Hepatology 20081101

• [Functional imaging in Binswanger's disease].

  Rinsho shinkeigaku = Clinical neurology 20081101

• Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.

  Methods and findings in experimental and clinical pharmacology 20081101

• Antinociceptive property of intrathecal and intraperitoneal administration of a novel water-soluble isoindolin-1-one derivative, JM 1232 (-) in rats.

  European journal of pharmacology 20081031

• S-ketamine and GABA-A-receptor interaction in humans: an exploratory study with I-123-iomazenil SPECT.

  Human psychopharmacology 20081001

• Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice.

  Neuropharmacology 20081001

• Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions.

  British journal of clinical pharmacology 20081001

• Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography.

  Archives of general psychiatry 20081001

• Idiopathic recurrent stupor mimicking status epilepticus.

  Singapore medical journal 20081001

• [Flumazenil].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20081001

• [Update on the management of hepatic encephalopathy].

  Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20081001

• Anticonvulsant effect of a natural compound alpha,beta-epoxy-carvone and its action on the nerve excitability.

  Neuroscience letters 20080926

• Intra-periaqueductal gray matter injections of midazolam fail to alter anxiety in plus-maze experienced mice.

  Brain research 20080922

• 6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors.

  European journal of pharmacology 20080904

• 11C-flumazenil positron emission tomography demonstrates reduction of both global and local cerebral benzodiazepine receptor binding in a patient with Stiff Person Syndrome.

  Journal of neurology 20080901

• Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission.

  Behavioural pharmacology 20080901

• Comparison of PET and DW/PW-MRI in acute ischemic stroke.

  The Keio journal of medicine 20080901

• Involvement of the GABA/benzodiazepine receptor in the axiolytic-like effect of nociceptin/orphanin FQ.

  European journal of pharmacology 20080820

• Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.

  European journal of pharmacology 20080820

• Ethyl 8-fluoro-6-(3-nitrophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate as novel, highly potent, and safe antianxiety agent.

  Journal of medicinal chemistry 20080814

• Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.

  The journal of pain : official journal of the American Pain Society 20080801

• GABA(A) signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze.

  Peptides 20080801

• Chrysin induces hyperalgesia via the GABAA receptor in mice.

  Planta medica 20080801

• Delayed-onset hepatic encephalopathy induced by zolpidem: a case report.

  Clinics (Sao Paulo, Brazil) 20080801

• In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist.

  Biological psychiatry 20080715

• Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.

  Journal of medicinal chemistry 20080710

• Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.

  Molecular pharmacology 20080701

• The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABA(A) receptors.

  Neuroscience research 20080701

• Effect of diazepam on the runway method using priming stimulation of intracranial self stimulation behavior.

  Journal of pharmacological sciences 20080701

• [Patient awakening from anesthesia was re-sedated by administration of flumazenil].

  Masui. The Japanese journal of anesthesiology 20080701

• Adenosine receptor agonists attenuate the development of diazepam withdrawal-induced sensitization in mice.

  European journal of pharmacology 20080624

• Midazolam inhibits cardiac nociception evoked by coronary artery occlusion in rats.

  European journal of anaesthesiology 20080601

• Reversal of paradoxical excitement to diazepam sedation.

  Paediatric anaesthesia 20080601

• Measurement of GABAA receptor binding in vivo with [11C]flumazenil: a test-retest study in healthy subjects.

  NeuroImage 20080601

• Midazolam attenuates the antinociception induced by d-serine or morphine at the supraspinal level in rats.

  European journal of pharmacology 20080531

• Reduced GABA neurotransmission underlies hyperalgesia induced by repeated forced swimming stress.

  Behavioural brain research 20080516

• Measurement of the 11C-flumazenil binding in the visual cortex predicts the prognosis of hemianopia.

  Journal of the neurological sciences 20080515

• Anticonvulsive effects of intracerebroventricular administration of rutin in rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20080515

• PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats.

  Brain research 20080507

• Iatrogenic delirium and coma: a 'near miss'.

  Chest 20080501

• Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.

  Bioorganic & medicinal chemistry 20080415

• Pharmacological evaluation of [123I]-CLINDE: a radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS).

  European journal of nuclear medicine and molecular imaging 20080401

• Anticonvulsant and anxiolytic-like effects of compounds isolated from Polygala sabulosa (Polygalaceae) in rodents: in vitro and in vivo interactions with benzodiazepine binding sites.

  Psychopharmacology 20080401

• Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy.

  Epilepsy & behavior : E&B 20080401

• Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice.

  Neuroscience research 20080401

• Rectal Flumazenil can save the day.

  Paediatric anaesthesia 20080401

• Short-term plasticity of central benzodiazepine receptors in status epilepticus: case report.

  Acta neurologica Scandinavica 20080401

• [(11)C]flumazenil positron emission tomography analyses of brain gamma-aminobutyric acid type A receptors in Angelman syndrome.

  The Journal of pediatrics 20080401

• Midazolam administration reverses thermal hyperalgesia and prevents gamma-aminobutyric acid transporter loss in a rodent model of neuropathic pain.

  Anesthesia and analgesia 20080401

• Positron emission tomography and target-controlled infusion for precise modulation of brain drug concentration.

  Nuclear medicine and biology 20080401

• Flumazenil in the treatment of dizziness and vegetative symptoms after intravenous infusion of paclitaxel.

  Onkologie 20080401

• Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301

• Possible GABAergic modulation in the protective effect of zolpidem in acute hypoxic stress-induced behavior alterations and oxidative damage.

  Neurochemical research 20080301

• Comparison of plasma input and reference tissue models for analysing [(11)C]flumazenil studies.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080301

• Decreased chronic-stage cortical 11C-flumazenil binding after focal ischemia-reperfusion in baboons: a marker of selective neuronal loss?

  Stroke 20080301

• MRI-based correction for partial-volume effect improves detectability of intractable epileptogenic foci on 123I-iomazenil brain SPECT images.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080301

• Treatment of methamphetamine dependence.

  Mayo Clinic proceedings 20080301

• [Poisoning by liquid ecstasy (GHB) in hospital emergency departments of Barcelona: a 2-years study].

  Medicina clinica 20080301

• Epilepsy surgery: eligibility criteria and presurgical evaluation.

  Dialogues in clinical neuroscience 20080301

• GABA(A) receptors in normal development and seizures: friends or foes?

  Current neuropharmacology 20080301

• Role of neuroimaging in the presurgical evaluation of epilepsy.

  Journal of clinical neurology (Seoul, Korea) 20080301

• Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• The anxiolytic-like effect of the selective 5-HT6 receptor antagonist SB-399885: the impact of benzodiazepine receptors.

  European journal of pharmacology 20080212

• Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats.

  Journal of feline medicine and surgery 20080201

• Partial volume corrected image derived input functions for dynamic PET brain studies: methodology and validation for [11C]flumazenil.

  NeuroImage 20080201

• Modulation of synaptic GABAA receptor function by zolpidem in substantia nigra pars reticulata.

  Acta pharmacologica Sinica 20080201

• Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study.

  Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080201

• Investigation of the anxiolytic effects of linalool, a lavender extract, in the male Sprague-Dawley rat.

  AANA journal 20080201

• Impact of attenuation correction strategies on the quantification of High Resolution Research Tomograph PET studies.

  Physics in medicine and biology 20080107

• [11C]Flumazenil PET in temporal lobe epilepsy: do we need an arterial input function or kinetic modeling?

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080101

• Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder.

  Molecular psychiatry 20080101

• Comparative analysis of MR imaging, ictal SPECT and EEG in temporal lobe epilepsy: a prospective IAEA multi-center study.

  European journal of nuclear medicine and molecular imaging 20080101

• Euphorbia hirta reverses chronic stress-induced anxiety and mediates its action through the GABA(A) receptor benzodiazepine receptor-Cl(-) channel complex.

  Journal of neural transmission (Vienna, Austria : 1996) 20080101

• Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans.

  Anesthesia and analgesia 20080101

• Acute poisonings treated in hospitals in Oslo: a one-year prospective study (II): clinical outcome.

  Clinical toxicology (Philadelphia, Pa.) 20080101

• Midazolam and other benzodiazepines.

  Handbook of experimental pharmacology 20080101

• [123I iomazenil SPECT and identification of the epileptogenic tubers in patients with tuberous sclerosis].

  No to hattatsu = Brain and development 20080101

• Clinical review: Major consequences of illicit drug consumption.

  Critical care (London, England) 20080101

• Molecular and diffusion tensor imaging of epileptic networks.

  Epilepsia 20080101

• [Acute asthma and coma in Emergency Department: a case report].

  Recenti progressi in medicina 20080101

• Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.

  BMC pharmacology 20080101

• Delirium and its treatment.

  CNS drugs 20080101

• The auditory cortex of the bat Phyllostomus discolor: Localization and organization of basic response properties.

  BMC neuroscience 20080101

• Effect of flumazenil on disturbance of equilibrium function induced by midazolam.

  Anesthesia progress 20080101

• Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice.

  Pharmacological reports : PR 20080101

• Pre-hospital treatment of acute poisonings in Oslo.

  BMC emergency medicine 20080101

• Pediatric procedural sedation and analgesia.

  Journal of emergencies, trauma, and shock 20080101

• Carisoprodol-induced amnestic state.

  Indian journal of psychiatry 20080101

• Effect of Withania somnifera on Sleep-Wake Cycle in Sleep-Disturbed Rats: Possible GABAergic Mechanism.

  Indian journal of pharmaceutical sciences 20080101

• The effect of sympathetic antagonists on the antidepressant action of alprazolam.

  The Libyan journal of medicine 20080101

• Tryptophan research in panic disorder.

  International journal of tryptophan research : IJTR 20080101

• Effect of the diazepam-binding inhibitor-derived peptide, octadecaneuropeptide, on food intake in goldfish.

  Neuroscience 20071205

• Insomnia: a ticking clock for depression?

  Journal of psychiatric research 20071201

• Emerging synergisms between drugs and physiologically-patterned weak magnetic fields: implications for neuropharmacology and the human population in the twenty-first century.

  Current neuropharmacology 20071201

• Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis.

  European journal of pharmacology 20071128

• Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects.

  Journal of the neurological sciences 20071115

• Effect of flumazenil-augmentation on microsleep and mood in depressed patients during partial sleep deprivation.

  Journal of psychiatric research 20071101

• The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress.

  Alcoholism, clinical and experimental research 20071101

• Partial antagonization of midazolam-medetomidine-ketamine in cats--atipamezole versus combined atipamezole and flumazenil.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20071101

• [Drug dependence syndrome as a side effect of medical drug use].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine.

  Veterinary research communications 20071001

• Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon.

  Neuropeptides 20071001

• Anxiolytic-like effects of obovatol isolated from Magnolia obovata: involvement of GABA/benzodiazepine receptors complex.

  Progress in neuro-psychopharmacology & biological psychiatry 20071001

• Delayed postoperative agitation in a child after preoperative midazolam.

  Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20071001

• Open-label study of a proprietary treatment program targeting type A gamma-aminobutyric acid receptor dysregulation in methamphetamine dependence.

  Mayo Clinic proceedings 20071001

• Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.

  AANA journal 20071001

• Zolpidem modified-release in insomnia.

  Neuropsychiatric disease and treatment 20071001

• Carisoprodol withdrawal induced delirium: A case study.

  Neuropsychiatric disease and treatment 20071001

• Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators.

  The Journal of biological chemistry 20070907

• Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20070901

• Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands.

  Biopharmaceutics & drug disposition 20070901

• Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats.

  Alcoholism, clinical and experimental research 20070901

• 6,2'-Dihydroxyflavone, a subtype-selective partial inverse agonist of GABAA receptor benzodiazepine site.

  Neuropharmacology 20070901

• Biological clocks and the practice of psychiatry.

  Dialogues in clinical neuroscience 20070901

• Gefitinib and high-dose fractionated radiotherapy for carcinomatous encephalitis from non-small cell lung carcinoma.

  Biologics : targets & therapy 20070901

• Flumazenil selectively prevents the increase in alpha(4)-subunit gene expression and an associated change in GABA(A) receptor function induced by ethanol withdrawal.

  Journal of neurochemistry 20070801

• Systemic administration of the benzodiazepine receptor partial inverse agonist FG-7142 disrupts corticolimbic network interactions.

  Synapse (New York, N.Y.) 20070801

• Usefulness of 123I-iomazenil single-photon emission computed tomography in discriminating between mesial and lateral temporal lobe epilepsy in patients in whom magnetic resonance imaging demonstrates normal findings.

  Journal of neurosurgery 20070801

• Pharmacological characterization of the receptor mediating the anorexigenic action of the octadecaneuropeptide: evidence for an endozepinergic tone regulating food intake.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701

• Should a benzodiazepine antagonist be used in unconscious patients presenting to the emergency department?

  Resuscitation 20070701

• Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure.

  Psychopharmacology 20070701

• Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy.

  Epilepsia 20070701

• Propofol for procedural sedation in the emergency department.

  Emergency medicine journal : EMJ 20070701

• CNS 7056: a novel ultra-short-acting Benzodiazepine.

  Anesthesiology 20070701

• Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity.

  Neuropharmacology 20070701

• Radiosynthesis and biological evaluation of an 18F-labeled derivative of the novel pyrazolopyrimidine sedative-hypnotic agent indiplon.

  Nuclear medicine and biology 20070701

• Reduced gamma-aminobutyric acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder.

  Archives of general psychiatry 20070701

• Effect of withdrawal of diazepam or morphine treatment on gastric motility (charcoal meal test) in mice: possible role of different central and peripheral receptors.

  Indian journal of experimental biology 20070701

• Anxiolytic-like effects of sinapic acid in mice.

  Life sciences 20070627

• Flumazenil-sensitive dose-related physical dependence in planarians produced by two benzodiazepine and one non-benzodiazepine benzodiazepine-receptor agonists.

  European journal of pharmacology 20070614

• The CRF1 receptor antagonist R121919 attenuates the neuroendocrine and behavioral effects of precipitated lorazepam withdrawal.

  Psychopharmacology 20070601

• Elevated zero maze: a paradigm to evaluate antianxiety effects of drugs.

  Methods and findings in experimental and clinical pharmacology 20070601

• [A study of 355 consecutive acute poisoning cases admitted to an emergency ward at Copenhagen University Hospital, Bispebjerg in 2001].

  Ugeskrift for laeger 20070507

• Possible involvement of GABA A-benzodiazepine receptor in the anxiolytic-like effect induced by Passiflora actinia extracts in mice.

  Journal of ethnopharmacology 20070504

• FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501

• Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.

  Psychopharmacology 20070501

• Zolpidem modulates GABA(A) receptor function in subthalamic nucleus.

  Neuroscience research 20070501

• Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 20070501

• Brain activity affects dynamic but not static autoregulation.

  Experimental neurology 20070501

• Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice.

  Pharmacology, biochemistry, and behavior 20070501

• Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium.

  Environmental health perspectives 20070501

• [Anxiety, panic and the hypothalamic-pituitary-adrenal axis].

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20070501

• Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices.

  European journal of pharmacology 20070430

• Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.

  Journal of medicinal chemistry 20070405

• Anti-anxiety effects of Apocynum venetum L. in the elevated plus maze test.

  Journal of ethnopharmacology 20070404

• Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of GABAergic and opioids systems.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20070401

• Unplanned 'unconsciousness' at Caesarean section: hysteria or drug reaction?

  International journal of obstetric anesthesia 20070401

• Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal.

  Alcoholism, clinical and experimental research 20070401

• Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism.

  Pharmacology, biochemistry, and behavior 20070401

• UK drug analysis prints and anaesthetic adverse drug reactions.

  Pharmacoepidemiology and drug safety 20070301

• The novel anxiolytic ELB139 displays selectivity to recombinant GABA(A) receptors different from diazepam.

  Neuropharmacology 20070301

• Comparison of lorazepam [7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] occupancy of rat brain gamma-aminobutyric acid(A) receptors measured using in vivo [3H]flumazenil (8-fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester) binding and [11C]flumazenil micro-positron emission tomography.

  The Journal of pharmacology and experimental therapeutics 20070301

• Fast cardiologist-administered midazolam for electrical cardioversion of atrial fibrillation.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20070301

• Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent.

  Neuropharmacology 20070201

• Benzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input.

  Neuropharmacology 20070201

• Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats.

  Behavioural pharmacology 20070201

• The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices.

  Anesthesia and analgesia 20070201

• Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia.

  Archives of general psychiatry 20070201

• Coma cocktail: a role for flumazenil?

  British journal of hospital medicine (London, England : 2005) 20070201

• Diazepam-induced disruption of classically-conditioned fear-potentiation of late-latency auditory evoked potentials is prevented by flumazenil given before, but not after, CS/US pairing.

  Journal of psychopharmacology (Oxford, England) 20070101

• Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101

• Assessment of regional GABA(A) receptor binding using 18F-fluoroflumazenil positron emission tomography in spastic type cerebral palsy.

  NeuroImage 20070101

• Effect of GABAergic ligands on the anxiolytic-like activity of DOI (a 5-HT(2A/2C) agonist) in the four-plate test in mice.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070101

• In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070101

• Association of vascular parkinsonism with impaired neuronal integrity in the striatum.

  Journal of neural transmission (Vienna, Austria : 1996) 20070101

• Use of a novel mouse genotype to model acute benzodiazepine withdrawal.

  Behavior genetics 20070101

• ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study.

  Pharmacology, biochemistry, and behavior 20070101

• Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management.

  Clinical toxicology (Philadelphia, Pa.) 20070101

• Neurobiology of memory and anxiety: from genes to behavior.

  Neural plasticity 20070101

• Characterization of the interaction between fenamates and hippocampal neuron GABA(A) receptors.

  Neurochemistry international 20070101

• Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors.

  BMC complementary and alternative medicine 20070101

• Multimodality data integration in epilepsy.

  International journal of biomedical imaging 20070101

• Pharmacokinetic considerations in clinical toxicology: clinical applications.

  Clinical pharmacokinetics 20070101

• Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex.

  Frontiers in integrative neuroscience 20070101

• Effects of calcium channel blockers on antidepressant action of Alprazolam and Imipramine.

  The Libyan journal of medicine 20070101

• Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action.

  Progress in neuro-psychopharmacology & biological psychiatry 20061230

• Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

  Progress in neuro-psychopharmacology & biological psychiatry 20061230

• Felbamate is a subunit selective modulator of recombinant gamma-aminobutyric acid type A receptors expressed in Xenopus oocytes.

  European journal of pharmacology 20061215

• The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.

  The Journal of pharmacology and experimental therapeutics 20061201

• Prolonged unconsciousness in a patient on automated peritoneal dialysis.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20061201

• Changes in pulse oximetry levels and factors affecting oxygen saturation during routine upper gastrointestinal endoscopy with or without sedation.

  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20061201

• A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March.

  Pharmacology, biochemistry, and behavior 20061201

• Psychopharmacology of topiramate: from epilepsy to bipolar disorder.

  Neuropsychiatric disease and treatment 20061201

• Anxiolytic effects of the aqueous extract of Uncaria rhynchophylla.

  Journal of ethnopharmacology 20061124

• Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs.

  European journal of pharmacology 20061121

• An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze.

  Psychopharmacology 20061101

• GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon.

  Synapse (New York, N.Y.) 20061101

• Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET.

  Nuclear medicine communications 20061101

• Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas.

  Stroke 20061101

• Chronic intragastric administration of gamma-butyrolactone produces physical dependence in baboons.

  Psychopharmacology 20061101

• Adequacy of antidote stocking in British Columbia hospitals: the 2005 Antidote Stocking Study.

  CJEM 20061101

• The proconvulsant effects of the GABAA alpha5 subtype-selective compound RY-080 may not be alpha5-mediated.

  European journal of pharmacology 20061024

• Intravenous flumazenil for Parkinson's disease: a single dose, double blind, placebo controlled, cross-over trial.

  Movement disorders : official journal of the Movement Disorder Society 20061001

• Effects of diazepam on 125I-iomazenil-benzodiazepine receptor binding and epileptic seizures in the El mouse.

  Annals of nuclear medicine 20061001

• Optimization algorithms and weighting factors for analysis of dynamic PET studies.

  Physics in medicine and biology 20060907

• Lorazepam-induced effects on silent period and corticomotor excitability.

  Experimental brain research 20060901

• A GABAA receptor mutation causing generalized epilepsy reduces benzodiazepine receptor binding.

  NeuroImage 20060901

• Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20060801

• Focal cortical dysplasia: pathophysiological approach.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20060801

• Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes.

  Psychopharmacology 20060801

• Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

  European journal of pharmacology 20060710

• Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701

• Tolerance to the antinociceptive effects of ethanol during ethanol withdrawal.

  Progress in neuro-psychopharmacology & biological psychiatry 20060701

• Protective effect of BR-16A, a polyherbal preparation against social isolation stress: possible GABAergic mechanism.

  Phytotherapy research : PTR 20060701

• Comparison of in vivo and ex vivo [3H]flumazenil binding assays to determine occupancy at the benzodiazepine binding site of rat brain GABAA receptors.

  Neuropharmacology 20060701

• Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion.

  Anesthesiology 20060701

• [Influence of benzodiazepines on 123I iomazenil SPECT].

  No to hattatsu = Brain and development 20060701

• Sexual assault and posttraumatic stress disorder: a review of the biological, psychological and sociological factors and treatments.

  McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060701

• Cardiotonic and sedative effects of Cecropia pachystachya Mart. (ambay) on isolated rat hearts and conscious mice.

  Journal of ethnopharmacology 20060615

• Pharmacological evaluation of an [(123)I] labelled imidazopyridine-3-acetamide for the study of benzodiazepine receptors.

  Life sciences 20060613

• Behavioral effects of opioid subtypes compared with benzodiazepines in the staircase paradigm.

  Behavioural brain research 20060603

• Neurosteroids, GABAA receptors, and ethanol dependence.

  Psychopharmacology 20060601

• Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder.

  Psychopharmacology 20060601

• Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites.

  Bioorganic & medicinal chemistry 20060601

• An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons.

  Neurochemistry international 20060601

• Acute and chronic effects of ramelteon in rhesus monkeys (Macaca mulatta): dependence liability studies.

  Behavioral neuroscience 20060601

• An investigation of flumazenil to antagonize gamma-hydroxybutyrate intoxication in a murine model.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20060601

• The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone.

  Neuropharmacology 20060501

• Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice.

  Psychopharmacology 20060501

• Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.

  Behavioural pharmacology 20060501

• Effects of drugs acting on the GABA-benzodiazepine receptor complex on flurothyl-induced seizures in Mongolian gerbils.

  European journal of pharmacology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Clinical evaluation of intranasal benzodiazepines, alpha-agonists and their antagonists in canaries.

  Veterinary anaesthesia and analgesia 20060501

• SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060501

• Acute treatment with pentobarbital alters the kinetics of in vivo receptor binding in the mouse brain.

  Nuclear medicine and biology 20060501

• The lack of bicuculline and picrotoxin influence on midazolam depressant action on brain oxygen consumption.

  Neuroscience letters 20060424

• Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.

  Journal of medicinal chemistry 20060420

• Discriminative stimulus effects of gamma-hydroxybutyrate: role of training dose.

  The Journal of pharmacology and experimental therapeutics 20060401

• Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.

  Epilepsia 20060401

• Diazepam enhances inotropic responses to dopamine in rat ventricular myocardium.

  Anesthesia and analgesia 20060301

• Evidence-based emergency medicine/systematic review abstract. Is flumazenil an effective treatment for hepatic encephalopathy?

  Annals of emergency medicine 20060301

• The alkaloid alstonine: a review of its pharmacological properties.

  Evidence-based complementary and alternative medicine : eCAM 20060301

• Danger of flumazenil use in pediatric status epilepticus.

  Pediatric emergency care 20060301

• Benzodiazepine receptor ligands. 8: synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy.

  Bioorganic & medicinal chemistry 20060201

• Pharmacological properties of GABAA receptors containing gamma1 subunits.

  Molecular pharmacology 20060201

• Autoradiographic localization and binding study of benzodiazepines receptor sites in carp brain (Cyprinus carpio L.).

  Journal of chemical neuroanatomy 20060201

• Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats.

  Neuropharmacology 20060201

• Differential behavioral effects of low efficacy positive GABAA modulators in combination with benzodiazepines and a neuroactive steroid in rhesus monkeys.

  British journal of pharmacology 20060201

• Cerebral oxygen metabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery disease.

  Stroke 20060201

• Actions of midazolam on excitatory transmission in dorsal horn neurons of adult rat spinal cord.

  Anesthesiology 20060201

• Use of Flumazenil in benzodiazepine overdose.

  Emergency medicine journal : EMJ 20060201

• Sedative effects of midazolam and xylazine with or without ketamine and detomidine alone following intranasal administration in Ring-necked Parakeets.

  Journal of the American Veterinary Medical Association 20060201

• Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice.

  Biological & pharmaceutical bulletin 20060201

• Biflavones from Rhus species with affinity for the GABA(A)/benzodiazepine receptor.

  Journal of ethnopharmacology 20060116

• Sedative, antiepileptic and antipsychotic effects of Spondias mombin L. (Anacardiaceae) in mice and rats.

  Journal of ethnopharmacology 20060116

• gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation.

  Biological psychiatry 20060115

• GABA(A) receptors mediate orexin-A induced stimulation of food intake.

  Neuropharmacology 20060101

• TPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates.

  The Journal of pharmacology and experimental therapeutics 20060101

• Focal glucose hypermetabolism in interictal state of West syndrome.

  Pediatric neurology 20060101

• Anti-conflict effects of benzodiazepines in rhesus monkeys: relationship with therapeutic doses in humans and role of GABAA receptors.

  Psychopharmacology 20060101

• Chemical immobilization of adult female Weddell seals with tiletamine and zolazepam: effects of age, condition and stage of lactation.

  BMC veterinary research 20060101

• What does flumazenil PET add to an evaluation for temporal lobectomy?

  Epilepsy currents 20060101

• Sedation and analgesia for gastrointestinal endoscopy during pregnancy.

  Gastrointestinal endoscopy clinics of North America 20060101

• [Participation of GABA--benzodiazepine receptor complex in the anxiolytic effect of piracetam].

  Eksperimental'naia i klinicheskaia farmakologiia 20060101

• A comparison of 3 routes of flumazenil administration to reverse benzodiazepine-induced desaturation in an animal model.

  Pediatric dentistry 20060101

• Antidote use in the critically ill poisoned patient.

  Journal of intensive care medicine 20060101

• [Midazolam (dormicump)--clinical practice guidelines].

  Medicinski pregled 20060101

• Adenosine receptor antagonists intensify the benzodiazepine withdrawal signs in mice.

  Pharmacological reports : PR 20060101

• Combination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathways.

  Journal of carcinogenesis 20060101

• Ligand-based approach to in silico pharmacology: nuclear receptor profiling.

  Journal of chemical information and modeling 20060101

• Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling.

  Pharmacological reports : PR 20060101

• The astrocytic GABA(A)/benzodiazepine-like receptor: the Joker receptor for benzodiazepine-mimetic drugs?

  Recent patents on CNS drug discovery 20060101

• Post-operative delirium after hip fracture treatment - a review of the current literature.

  Psycho-social medicine 20060101

• Effects of GABAergic modulators on food and cocaine self-administration in baboons.

  Drug and alcohol dependence 20051212

• Endozepines in recurrent stupor.

  Sleep medicine reviews 20051201

• Abnormal benzodiazepine receptor function in the depressive-like behavior of diabetic mice.

  Pharmacology, biochemistry, and behavior 20051201

• Selective neuronal damage and borderzone infarction in carotid artery occlusive disease: a 11C-flumazenil PET study.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051201

• Midazolam for patients undergoing upper gastrointestinal endoscopy: a prospective, single-blind and randomized study to determine the appropriate amount and time of initiation of endoscopy.

  Journal of gastroenterology and hepatology 20051201

• Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy.

  Metabolic brain disease 20051201

• Benzodiazepine involvement in LTP of the GABA-ergic IPSC in rat hippocampal CA1 neurons.

  Brain research 20051116

• Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand.

  Bioorganic & medicinal chemistry 20051115

• A comparison of chlordiazepoxide, bretazenil, L838,417 and zolpidem in a validated mouse Vogel conflict test.

  Psychopharmacology 20051101

• Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513.

  British journal of pharmacology 20051101

• Population plasma pharmacokinetics of 11C-flumazenil at tracer concentrations.

  British journal of clinical pharmacology 20051101

• Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells.

  Environmental health perspectives 20051101

• Individual differences in aggressive responding to intravenous flumazenil administration in adult male parolees.

  Journal of psychopharmacology (Oxford, England) 20051101

• Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice.

  European journal of pharmacology 20051031

• Negative GABA(A) modulators attenuate the discriminative stimulus effects of benzodiazepines and the neuroactive steroid pregnanolone in rhesus monkeys.

  Psychopharmacology 20051001

• Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates.

  European journal of pharmacology 20050905

• Comparison of the behavioral effects of bretazenil and flumazenil in triazolam-dependent and non-dependent baboons.

  European journal of pharmacology 20050905

• Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050901

• Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors.

  Psychoneuroendocrinology 20050901

• Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.

  Molecular pharmacology 20050901

• Dependence on zolpidem: two case reports of detoxification with flumazenil infusion.

  International clinical psychopharmacology 20050901

• Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS.

  Journal of neurology, neurosurgery, and psychiatry 20050901

• Subanesthetic ketamine does not affect 11C-flumazenil binding in humans.

  Anesthesia and analgesia 20050901

• Does the panic attack activate the hypothalamic-pituitary-adrenal axis?

  Anais da Academia Brasileira de Ciencias 20050901

• On the mechanism of anticonvulsant effect of tramadol in mice.

  Pharmacology, biochemistry, and behavior 20050901

• Genetic influences in emotional dysfunction and alcoholism-related brain damage.

  Neuropsychiatric disease and treatment 20050901

• Differential effects of acute diazepam on emotional and neutral memory tasks in acutely hospitalized depressed patients.

  Neuropsychiatric disease and treatment 20050901

• Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder.

  Brain research. Molecular brain research 20050818

• Characterization in rats of the anxiolytic potential of ELB139 [1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a new agonist at the benzodiazepine binding site of the GABAA receptor.

  The Journal of pharmacology and experimental therapeutics 20050801

• GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study.

  Psychopharmacology 20050801

• A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist.

  Psychopharmacology 20050801

• In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708.

  Neuropharmacology 20050801

• Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking.

  Archives of general psychiatry 20050801

• Chronic treatment with flumazenil enhances binding sites for convulsants at recombinant alpha(1)beta(2)gamma(2S) GABA(A) receptors.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050801

• Selective GABAA alpha5 benzodiazepine inverse agonist antagonizes the neurobehavioral actions of alcohol.

  Alcoholism, clinical and experimental research 20050801

• Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rats.

  Psychopharmacology 20050701

• Bidirectional effects of benzodiazepine binding site ligands on active avoidance acquisition and retention: differential antagonism by flumazenil and beta-CCt.

  Psychopharmacology 20050701

• Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain.

  Neurochemistry international 20050701

• Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.

  Pharmacology, biochemistry, and behavior 20050701

• Placebo in emotional processing--induced expectations of anxiety relief activate a generalized modulatory network.

  Neuron 20050616

• Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists.

  Bioorganic & medicinal chemistry letters 20050615

• Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study.

  Brain : a journal of neurology 20050601

• Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET.

  Brain : a journal of neurology 20050601

• The four-plates test-retest paradigm to discriminate anxiolytic effects.

  Psychopharmacology 20050601

• Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.

  Annals of emergency medicine 20050601

• Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis.

  Epilepsia 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Changes in peripheral benzodiazepine receptors in patients with bipolar disorder.

  Neuropsychiatric disease and treatment 20050601

• Two flavonoids from Artemisia herba-alba Asso with in vitro GABAA-benzodiazepine receptor activity.

  Journal of ethnopharmacology 20050513

• Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats.

  Biological & pharmaceutical bulletin 20050501

• Pharmacological modulation of repeated ethanol withdrawal-induced anxiety-like behavior differs in alcohol-preferring P and Sprague-Dawley rats.

  Pharmacology, biochemistry, and behavior 20050501

• The role of flumazenil in self harm with benzodiazepines: to give or not to give?

  Hospital medicine (London, England : 1998) 20050501

• High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives.

  Journal of medicinal chemistry 20050421

• 6-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes.

  European journal of pharmacology 20050411

• (+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1beta2gamma2L GABA(A) receptors.

  Biochemical pharmacology 20050401

• Classic benzodiazepines modulate the open-close equilibrium in alpha1beta2gamma2L gamma-aminobutyric acid type A receptors.

  Anesthesiology 20050401

• Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats.

  Medical science monitor : international medical journal of experimental and clinical research 20050401

• Ethyl 5-isopropoxy-4-methyl-beta-carboline-3-carboxylate: structural determinants of benzodiazepine-receptor antagonism.

  Acta crystallographica. Section C, Crystal structure communications 20050401

• Biological properties of 2'-[18F]fluoroflumazenil for central benzodiazepine receptor imaging.

  Nuclear medicine and biology 20050401

• Modulation of ethanol withdrawal-induced anxiety-like behavior during later withdrawals by treatment of early withdrawals with benzodiazepine/gamma-aminobutyric acid ligands.

  Alcoholism, clinical and experimental research 20050401

• Flumazenil-induced improvement of the central dopaminergic system in rats with acute hepatic failure.

  Journal of neurosurgical anesthesiology 20050401

• Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: application to clinical study.

  Farmaco (Societa chimica italiana : 1989) 20050401

• [Ischemic brain infarction after an air embolism. Case report].

  Revista medica de Chile 20050401

• Bidirectional effects of benzodiazepine binding site ligands in the passive avoidance task: differential antagonism by flumazenil and beta-CCt.

  Behavioural brain research 20050330

• Role of GABA-ergic and serotonergic systems in the anxiolytic-like mechanism of action of a 5-HT-moduline antagonist in the mouse elevated plus maze.

  Behavioural brain research 20050330

• Benzodiazepines and heightened aggressive behavior in rats: reduction by GABA(A)/alpha(1) receptor antagonists.

  Psychopharmacology 20050301

• Flumazenil-precipitated withdrawal in healthy volunteers following repeated diazepam exposure.

  Psychopharmacology 20050301

• Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions.

  Amino acids 20050201

• The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action.

  The Journal of pharmacy and pharmacology 20050201

• Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography.

  Nuclear medicine and biology 20050201

• Benzodiazepine system is involved in hyperalgesia in rats induced by the exposure to extremely low frequency magnetic fields.

  Archives of pharmacal research 20050201

• Acetylcholine in the accumbens is decreased by diazepam and increased by benzodiazepine withdrawal: a possible mechanism for dependency.

  European journal of pharmacology 20050131

• Haloperidol plus promethazine for psychosis induced aggression.

  The Cochrane database of systematic reviews 20050125

• Activity of a traditional South African epilepsy remedy in the GABA-benzodiazepine receptor assay.

  Journal of ethnopharmacology 20050115

• Enhancement of benzodiazepine binding sites following chronic treatment with flumazenil.

  European journal of pharmacology 20050110

• Rodent pharmacokinetics and receptor occupancy of the GABAA receptor subtype selective benzodiazepine site ligand L-838417.

  Biopharmaceutics & drug disposition 20050101

• [Utility of routine use of reversion after sedation in outpatient colonoscopy].

  Gastroenterologia y hepatologia 20050101

• Benzodiazepine effect of (125)I-iomazenil-benzodiazepine receptor binding and serum corticosterone level in a rat model.

  Nuclear medicine and biology 20050101

• Differentiating midazolam over-sedation from neurological damage in the intensive care unit.

  Critical care (London, England) 20050101

• [Central hemodynamic changes in children reoperated on for congenital spinal cord hernia using balanced anesthesia based on midasolam and propofol].

  Anesteziologiia i reanimatologiia 20050101

• Central-type benzodiazepine receptors and epileptogenesis: basic mechanisms and clinical validity.

  Epilepsia 20050101

• Between benzodiazepine over-sedation and neurological damage.

  Critical care (London, England) 20050101

• Effect of flumazenil on recovery from sevoflurane anesthesia in children premedicated with oral midazolam before undergoing herniorrhaphy with or without caudal analgesia.

  Journal of anesthesia 20050101

• Zopiclone overdose responsive to flumazenil.

  Clinical toxicology (Philadelphia, Pa.) 20050101

• Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20050101

• Chronic exposure of cells expressing recombinant GABAA receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine binding sites.

  Life sciences 20041203

• Discriminative stimulus effects in rats of SR-141716 (rimonabant), a cannabinoid CB1 receptor antagonist.

  Psychopharmacology 20041201

• Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy.

  Metabolic brain disease 20041201

• Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint.

  Metabolic brain disease 20041201

• The coma cocktail: indications, contraindications, adverse effects, proper dose, and proper route.

  Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20041201

• Melatonin inhibits the development of tolerance to U-50,488H analgesia via benzodiazepine-GABAAergic mechanisms.

  Pharmacology, biochemistry, and behavior 20041201

• Clinical utility of 11C-flumazenil positron emission tomography in intractable temporal lobe epilepsy.

  Neurology India 20041201

• In vivo pharmacological characterization of indiplon, a novel pyrazolopyrimidine sedative-hypnotic.

  The Journal of pharmacology and experimental therapeutics 20041101

• Characterization of the interaction of indiplon, a novel pyrazolopyrimidine sedative-hypnotic, with the GABAA receptor.

  The Journal of pharmacology and experimental therapeutics 20041101

• Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans.

  Anesthesia and analgesia 20041101

• Multiple GABAA receptor subtypes regulate hippocampal ripple oscillations.

  The European journal of neuroscience 20041001

• Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures.

  Epilepsia 20041001

• Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and beta-CCt.

  Pharmacology, biochemistry, and behavior 20041001

• Difficulties in assessing brain death in a case of benzodiazepine poisoning with persistent cerebral blood flow.

  Human & experimental toxicology 20041001

• Evaluation of the use of a standard input function for compartment analysis of [123I]iomazenil data: factors influencing the quantitative results.

  Annals of nuclear medicine 20041001

• Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats.

  Synapse (New York, N.Y.) 20040915

• Determination of flumazenil in human plasma by liquid chromatography-electrospray ionisation tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905

• Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling.

  Neuropharmacology 20040901

• Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials.

  Anesthesia and analgesia 20040901

• Asystole and bradycardia related to anesthetic induction during ECT: a case report.

  The journal of ECT 20040901

• Correct localization of epileptogenic focus with I-123 iomazenil cerebral benzodiazepine receptor imaging: a case report of temporal lobe epilepsy with discordant ictal cerebral blood flow SPECT.

  Annals of nuclear medicine 20040901

• Probability of cortical infarction predicted by flumazenil binding and diffusion-weighted imaging signal intensity: a comparative positron emission tomography/magnetic resonance imaging study in early ischemic stroke.

  Stroke 20040801

• Facilitation of cholinergic transmission by combined treatment of ondansetron with flumazenil after cortical cholinergic deafferentation.

  Neuropharmacology 20040801

• Emergency drug availability on general paediatric units.

  Resuscitation 20040801

• Flumazenil positron emission tomography and other ligands for functional imaging.

  Neuroimaging clinics of North America 20040801

• Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization.

  Journal of mass spectrometry : JMS 20040801

• Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.

  Biological psychiatry 20040715

• GABAA receptor modulation of trigeminovascular nociceptive neurotransmission by midazolam is antagonized by flumazenil.

  Brain research 20040709

• Analysis of microsomal metabolic stability using high-flow-rate extraction coupled to capillary liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705

• Alprazolam is relatively more toxic than other benzodiazepines in overdose.

  British journal of clinical pharmacology 20040701

• [Effect of flumazenil on hypoglossal and phrenic nerves activities in rabbits].

  Masui. The Japanese journal of anesthesiology 20040701

• Effectiveness of antagonists for tiletamine-zolazepam/xylazine immobilization in female white-tailed deer.

  Journal of wildlife diseases 20040701

• Effects of GABA modulators on the repeated acquisition of response sequences in squirrel monkeys.

  Journal of the experimental analysis of behavior 20040701

• Use of a standardized uptake value for parametric in vivo imaging of benzodiazepine receptor distribution on [11C]flumazenil brain PET.

  European journal of nuclear medicine and molecular imaging 20040601

• Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.

  The Journal of physiology 20040601

• Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine.

  American family physician 20040601

• Anaesthesia with midazolam/medetomidine/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine/ketamine and medetomidine/ketamine.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040601

• [Functional neuroimaging in adults].

  Revue neurologique 20040601

• The Discriminative stimulus effects of gamma-hydroxybutyrate and related compounds in rats discriminating baclofen or diazepam: The role of GABA(B) and GABA(A) receptors.

  The Journal of pharmacology and experimental therapeutics 20040501

• Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.

  British journal of pharmacology 20040501

• GABA A receptor abnormalities in Prader-Willi syndrome assessed with positron emission tomography and [11C]flumazenil.

  NeuroImage 20040501

• Reversal of an antihistamine-induced coma with flumazenil.

  Pediatric emergency care 20040501

• Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors.

  European journal of pharmacology 20040426

• Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis: a positron emission tomography study.

  Stroke 20040401

• Electrophysiological and behavioral effects of zolpidem in rat globus pallidus.

  Experimental neurology 20040401

• GABAA/alpha1 receptor agonists and antagonists: effects on species-typical and heightened aggressive behavior after alcohol self-administration in mice.

  Psychopharmacology 20040301

• In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301

• Response to flumazenil in the late luteal phase and follicular phase of the menstrual cycle in healthy control females.

  Psychopharmacology 20040301

• Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.

  The Journal of pharmacology and experimental therapeutics 20040301

• Validation of a multiwell gamma-counter for measuring high-pressure liquid chromatography metabolite profiles.

  Journal of nuclear medicine technology 20040301

• Reversible anesthesia of captive California sea lions (Zalophus californianus) with medetomidine, midazolam, butorphanol, and isoflurane.

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040301

• Benzodiazepine-sensitive GABA(A) receptors in the commissural subnucleus of the NTS are involved in the carotid chemoreceptor reflex in rats.

  Autonomic neuroscience : basic & clinical 20040227

• Diminished GABA(A) receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040201

• Flumazenil does not affect intracortical motor excitability in humans: a transcranial magnetic stimulation study.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20040201

• 125I-iomazenil - benzodiazepine receptor binding and serum corticosterone level during psychological stress in a rat model.

  Nuclear medicine and biology 20040201

• Biological evaluation of 2'-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET.

  Nuclear medicine and biology 20040201

• SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats.

  Alcohol (Fayetteville, N.Y.) 20040201

• [New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects].

  Gastroenterologia y hepatologia 20040201

• Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128

• Stress-induced increase of cortical dopamine metabolism: attenuation by a tachykinin NK1 receptor antagonist.

  European journal of pharmacology 20040119

• Use of the elevated T-maze to study anxiety in mice.

  Behavioural brain research 20040105

• Behavioral effects of flumazenil in the social conflict test in mice.

  Psychopharmacology 20040101

• Characterisation of [123I]iomazenil distribution in a rat model of focal cerebral ischaemia in relation to histopathological findings.

  European journal of nuclear medicine and molecular imaging 20040101

• Anticonvulsant and antiepileptogenic effects of GABAA receptor ligands in pentylenetetrazole-kindled mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20040101

• The influence of midazolam on active avoidance retrieval and acquisition rate in rats.

  Pharmacology, biochemistry, and behavior 20040101

• Inhibition of type A GABA receptors by L-type calcium channel blockers.

  Neuroscience 20040101

• Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101

• Effects of metabolite correction for arterial input function on quantitative receptor images with 11C-flumazenil in clinical positron emission tomography studies.

  Journal of computer assisted tomography 20040101

• Benzodiazepine receptor antagonists for hepatic encephalopathy.

  The Cochrane database of systematic reviews 20040101

• Oral triazolam sedation in implant dentistry.

  The Journal of oral implantology 20040101

• Flumazenil--treatment or toxin.

  Journal of toxicology. Clinical toxicology 20040101

• A near-fatal overdose of carisoprodol (SOMA): case report.

  Journal of toxicology. Clinical toxicology 20040101

• Benzodiazepine receptor distribution in severe intractable tinnitus.

  The international tinnitus journal 20040101

• Quantitative evaluation of central-type benzodiazepine receptors with [(125)I] Iomazenil in experimental epileptogenesis. I. The rat kainate model of temporal lobe epilepsy.

  Epilepsy research 20040101

• Quantitative evaluation of central-type benzodiazepine receptors with [(125)I]Iomazenil in experimental epileptogenesis: II. The rat cortical dysplasia model.

  Epilepsy research 20040101

• [Acute intoxication with baclofen].

  Przeglad lekarski 20040101

• [Neurobiology and pharmacotherapy of social phobia].

  L'Encephale 20040101

• Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031217

• [Hepatic encephalopathy--therapy].

  Deutsche medizinische Wochenschrift (1946) 20031212

• Quantification of human brain benzodiazepine receptors using [18F]fluoroethylflumazenil: a first report in volunteers and epileptic patients.

  European journal of nuclear medicine and molecular imaging 20031201

• Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols.

  Annals of emergency medicine 20031201

• Intravenous midazolam sedation in pediatric diagnostic upper digestive endoscopy. A prospective study in a general hospital.

  Romanian journal of gastroenterology 20031201

• [How do diazepam and flumazenil influence respiratory control by the activities of both hypoglossal and phrenic nerves in rabbits?].

  Masui. The Japanese journal of anesthesiology 20031201

• Newer aspects of hepatic encephalopathy.

  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20031201

• Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy.

  Neurochemistry international 20031101

• Characterization of endozepines in the human testicular tissue: effect of triakontatetraneuropeptide on testosterone secretion.

  The Journal of clinical endocrinology and metabolism 20031101

• Safe and efficacious use of procedural sedation and analgesia by nonanesthesiologists in a pediatric emergency department.

  Archives of pediatrics & adolescent medicine 20031101

• Continuous-infusion flumazenil in the management of chlordiazepoxide toxicity.

  Pharmacotherapy 20031101

• Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.

  Biological psychiatry 20031015

• Biphasic action of midazolam on GABAA receptor-mediated responses in rat sacral dorsal commissural neurons.

  Biochemical and biophysical research communications 20031003

• [Once more: the care duty of the physician in ambulatory administration of sedatives. Decision of the Federal Court, 4/8/2003-VI ZR 265/02].

  Deutsche medizinische Wochenschrift (1946) 20031002

• Extracts of kava (Piper methysticum) induce acute anxiolytic-like behavioral changes in mice.

  Psychopharmacology 20031001

• Flumazenil attenuates development of tolerance to diazepam after chronic treatment of mice with either isoflurane or diazepam.

  Anesthesia and analgesia 20031001

• An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.

  Journal of natural products 20031001

• Effect of zaleplon, a non-benzodiazepine hypnotic, on melatonin secretion in rabbits.

  Journal of pharmacological sciences 20031001

• The new toy.

  JEMS : a journal of emergency medical services 20031001

• Selective neuronal vulnerability following mild focal brain ischemia in the mouse.

  Brain pathology (Zurich, Switzerland) 20031001

• Prediction of malignant course in MCA infarction by PET and microdialysis.

  Stroke 20030901

• Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug.

  Molecular pharmacology 20030901

• [Sedation with intravenous midazolam during upper gastrointestinal endoscopy--changes in hemodynamics, oxygen saturation and memory].

  Masui. The Japanese journal of anesthesiology 20030901

• Hemoglobin metabolites mimic benzodiazepines and are possible mediators of hepatic encephalopathy.

  Blood 20030815

• Flumazenil and tacrine increase the effectiveness of ondansetron on scopolamine-induced impairment of spatial learning in rats.

  Psychopharmacology 20030801

• Propofol-induced anesthesia in mice is mediated by gamma-aminobutyric acid-A and excitatory amino acid receptors.

  Anesthesia and analgesia 20030801

• Defibrillation efficacy and pain perception of two biphasic waveforms for internal cardioversion of atrial fibrillation.

  Journal of cardiovascular electrophysiology 20030801

• Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze.

  Progress in neuro-psychopharmacology & biological psychiatry 20030801

• Quantitative in vivo measurement of central benzodiazepine receptors in the brain of cats by use of positron-emission tomography and [11C]flumazenil.

  American journal of veterinary research 20030801

• GABAergic inhibitory mechanisms for repetition-adaptivity in large-scale brain systems.

  NeuroImage 20030801

• Studies on the anticonvulsant effect of U50488H on maximal electroshock seizure in mice.

  Pharmacology, biochemistry, and behavior 20030801

• Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors.

  Bioorganic & medicinal chemistry letters 20030721

• Positron emission tomography in presurgical localization of epileptic foci.

  Ideggyogyaszati szemle 20030720

• Drugs acting at the GABAA receptor attenuate ethanol-induced gastric mucosal damage in vitro.

  Clinical and experimental pharmacology & physiology 20030701

• Novel one-pot one-step synthesis of 2'-[(18)F]fluoroflumazenil (FFMZ) for benzodiazepine receptor imaging.

  Nuclear medicine and biology 20030701

• Physical dependence in baboons chronically treated with low and high doses of diazepam.

  Behavioural pharmacology 20030701

• Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030701

• Extraction of epileptogenic foci from PET and SPECT images by fuzzy modeling and data fusion.

  NeuroImage 20030701

• Attenuation of the effect of progesterone and 4'-chlordiazepam on stress-induced immune responses by bicuculline.

  Indian journal of physiology and pharmacology 20030701

• Role of platelet activating factor in triazolobenzodiazepines-induced retrograde amnesia.

  Behavioural brain research 20030616

• [Criminal use of psychoactive drugs. A cluster of 4 cases].

  Medicina clinica 20030614

• Involvement of presynaptic 5-HT(1A) and benzodiazepine receptors in the anticonflict activity of 5-HT(1A) receptor antagonists.

  European journal of pharmacology 20030613

• Modification of morphine analgesia and tolerance by flumazenil in male and female rats.

  European journal of pharmacology 20030606

• Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients.

  Brain : a journal of neurology 20030601

• Flumazenil, a GABA antagonist, may improve features of Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20030601

• Tail-swing behavior: a novel animal model for anxiety.

  Methods and findings in experimental and clinical pharmacology 20030601

• NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists.

  Pharmacology, biochemistry, and behavior 20030601

• The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies.

  The Journal of pharmacology and experimental therapeutics 20030501

• Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats.

  The Journal of pharmacology and experimental therapeutics 20030501

• Potentiation of proopiomelanocortin gene expression in cultured pituitary cells by benzodiazepines.

  Anesthesiology 20030501

• Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors.

  Epilepsia 20030501

• Flumazenil is innocuous in a paroxysmal supraventricular tachycardia and radiofrequency ablation: a paediatric case report and review of the literature.

  Paediatric anaesthesia 20030501

• Flumazenil reverses a paradoxical reaction to intravenous midazolam in a child with uneventful prior exposure to midazolam.

  Paediatric anaesthesia 20030501

• Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats.

  Pharmacology, biochemistry, and behavior 20030501

• Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys.

  European journal of pharmacology 20030411

• Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells.

  Molecular pharmacology 20030401

• On the undecidability among kinetic models: from model selection to model averaging.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401

• Flumazenil-induced ballism.

  Journal of Korean medical science 20030401

• Anxiolytic-like effects of baicalein and baicalin in the Vogel conflict test in mice.

  European journal of pharmacology 20030319

• Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography.

  Synapse (New York, N.Y.) 20030301

• Gamma-aminobutyric acid neuropharmacological investigations on narcosis produced by nitrogen, argon, or nitrous oxide.

  Anesthesia and analgesia 20030301

• Presurgical evaluation of epilepsy by brain diffusion: MR-detected effects of flumazenil on the epileptogenic focus.

  Epilepsia 20030301

• Simple analytic method of 11C-flumazenil metabolite in blood.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030301

• Inhibitory effect of propofol on ketamine-induced c-Fos expression in the rat posterior cingulate and retrosplenial cortices is mediated by GABAA receptor activation.

  Acta anaesthesiologica Scandinavica 20030301

• Comparison of the cardiorespiratory effects of medetomidine-butorphanol-ketamine and medetomidine-butorphanol-midazolam in patas monkeys (Erythrocebus patas).

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20030301

• Toxicity of intravenous anaesthetics.

  Best practice & research. Clinical anaesthesiology 20030301

• The evaluation of cognitive function in the dementias: methodological and regulatory considerations.

  Dialogues in clinical neuroscience 20030301

• The efficacy of flumazenil in subclinical to mild hepatic encephalopathic ambulatory patients. A prospective, randomised, double-blind, placebo-controlled study.

  Swiss medical weekly 20030222

• [Poisonings with benzodiazepine-like drugs].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030220

• Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors.

  European journal of pharmacology 20030214

• Structural requirements for imidazobenzodiazepine binding to GABA(A) receptors.

  Molecular pharmacology 20030201

• The influence of midazolam and flumazenil on rat brain slices oxygen consumption.

  Pharmacological research 20030201

• The GABA(A) receptor mediates the hypnotic activity of melatonin in rats.

  Pharmacology, biochemistry, and behavior 20030201

• Effects of diazepam and flumazenil on food competition behavior in high- and low-aggression pigeons.

  Pharmacology, biochemistry, and behavior 20030201

• Is central benzodiazepine receptor imaging useful for the identification of epileptogenic foci in localization-related epilepsies?

  European journal of nuclear medicine and molecular imaging 20030201

• Modulation of inhibitory autapses and synapses on rat CA1 interneurones by GABA(A) receptor ligands.

  The Journal of physiology 20030201

• The effect of diazepam on motor cortical oscillations and corticomuscular coherence studied in man.

  The Journal of physiology 20030201

• Flumazenil reversal of lorazepam-induced acute delirium.

  The Journal of emergency medicine 20030201

• Pharmacological evaluation of (S)-8-[123I]iodobretazenil: a radioligand for in vivo studies of central benzodiazepine receptors.

  Nuclear medicine and biology 20030201

• Hepatic encephalopathy: nomenclature, pathogenesis and treatment.

  Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20030201

• Are there teratogenic risks associated with antidotes used in the acute management of poisoned pregnant women?

  Birth defects research. Part A, Clinical and molecular teratology 20030201

• [18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).

  Bioorganic & medicinal chemistry letters 20030120

• Immobilization stress-induced increment of lactate metabolism in the basolateral amygdaloid nucleus is attenuated by diazepam in the rat.

  European journal of pharmacology 20030117

• Prior exposure to the elevated plus-maze sensitizes mice to the acute behavioral effects of fluoxetine and phenelzine.

  European journal of pharmacology 20030117

• Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice.

  Life sciences 20030103

• Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.

  Psychopharmacology 20030101

• Effects of cholecystokinin tetrapeptide (CCK(4)) and of anxiolytic drugs on GABA outflow from the cerebral cortex of freely moving rats.

  Neurochemistry international 20030101

• Comment on the paper by Horowski and Dorow.

  Psychopharmacology 20030101

• Possible mechanism involved in the anticonvulsant action of butorphanol in mice.

  Pharmacology, biochemistry, and behavior 20030101

• Discriminative stimulus effects of positive GABAA modulators and other anxiolytics, sedatives, and anticonvulsants in untreated and diazepam-treated monkeys.

  The Journal of pharmacology and experimental therapeutics 20030101

• Flumazenil and dialysis for gabapentin-induced coma.

  The Annals of pharmacotherapy 20030101

• Review: flumazenil leads to clinical and electroencephalographic improvement in hepatic encephalopathy in patients with cirrhosis.

  ACP journal club 20030101

• Studies of peripheral benzodiazepine receptors in mussels: comparison between a polluted and a nonpolluted site.

  Ecotoxicology and environmental safety 20030101

• Panic-related responses to pentagastrin, flumazenil, and thyrotropin-releasing hormone in healthy volunteers.

  Depression and anxiety 20030101

• Adenosine A1 and benzodiazepine receptors and glucose metabolism in the visual structures of rats monocularly deprived by enucleation or eyelid suture at a sensitive period.

  Japanese journal of ophthalmology 20030101

• [Acute pharmacologic poisoning (I). Psychotropic and antiarrhythmic drugs].

  Anales del sistema sanitario de Navarra 20030101

• Poisons: initial assessment and management.

  Clinical medicine (London, England) 20030101

• Poisons: initial assessment and management.

  Clinical medicine (London, England) 20030101

• Effect of ergot alkaloids on 3H-flunitrazepam binding to mouse brain GABAA receptors.

  Collegium antropologicum 20030101

• An in vitro assay for predicting successful imaging radiotracers.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20030101

• Image-derived input function for [11C]flumazenil kinetic analysis in human brain.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20030101

• The effects of flumazenil on the antinociceptive actions of morphine in rats.

  Receptors & channels 20030101

• PET neuroreceptor imaging as predictor of severe cerebral ischemic insult.

  Acta neurochirurgica. Supplement 20030101

• Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis.

  Acta neurochirurgica. Supplement 20030101

• National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit.

  Journal of intensive care medicine 20030101

• Identification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513.

  The Journal of biological chemistry 20021220

• Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents.

  Journal of medicinal chemistry 20021219

• Accidental bromazepam intoxication in a dog.

  The Veterinary record 20021207

• Inhibitory effect of diazepam on muscarinic receptor-stimulated inositol 1,4,5-trisphosphate production in rat parotid acinar cells.

  British journal of pharmacology 20021201

• Experience with 123I-iomazenil SPECT in acute cerebral infarction.

  Nuclear medicine communications 20021201

• Flumazenil reduces midazolam-induced cognitive impairment without altering pharmacokinetics.

  Clinical pharmacology and therapeutics 20021201

• Effect of flumazenil on GABAA receptors in isolated rat hippocampal neurons.

  Neurochemical research 20021201

• Human models as tools in the development of psychotropic drugs.

  Dialogues in clinical neuroscience 20021201

• GABA(A) receptor antagonists enhance cortical acetylcholine release induced by 5-HT(3) receptor blockade in freely moving rats.

  Brain research 20021122

• Benzodiazepine receptors in the medial-posterior hypothalamus mediate the reduction of hippocampal theta frequency by chlordiazepoxide.

  Brain research 20021108

• The beta subunit determines the ion selectivity of the GABAA receptor.

  The Journal of biological chemistry 20021101

• 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic.

  The Journal of pharmacology and experimental therapeutics 20021101

• Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi.

  Biochemical pharmacology 20021101

• Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys.

  Psychopharmacology 20021101

• The correlation between cerebral glucose metabolism and benzodiazepine receptor density in the acute vegetative state.

  European journal of neurology 20021101

• No more coma cocktails. Using science to dispel myths & improve patient care.

  JEMS : a journal of emergency medical services 20021101

• Effects of GABA(A) compounds on mCPP drug discrimination in rats.

  Life sciences 20021018

• Flumazenil recovers diaphragm muscle dysfunction caused by midazolam in dogs.

  Anesthesia and analgesia 20021001

• Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parameters.

  NeuroImage 20021001

• Central-nervous side effects of midazolam during transesophageal echocardiography.

  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20021001

• Flumazenil antagonizes respiratory depression caused by diazepam and induces expiratory excitation of hypoglossal nerve.

  Masui. The Japanese journal of anesthesiology 20021001

• Emergency drugs.

  Dental clinics of North America 20021001

• Modulation of development of tolerance to anticonvulsant effect of diazepam by flumazenil.

  Indian journal of physiology and pharmacology 20021001

• Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study.

  Addiction biology 20021001

• The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam.

  Pharmacology, biochemistry, and behavior 20020901

• A randomised, controlled trial of cognitive and psychomotor recovery from midazolam sedation following reversal with oral flumazenil.

  Anaesthesia 20020901

• Quantitative analysis of benzodiazepine receptor in temporal lobe epilepsy: [(125)I]iomazenil autoradiographic study of surgically resected specimens.

  Epilepsia 20020901

• Transport of amentoflavone across the blood-brain barrier in vitro.

  Planta medica 20020901

• Mechanisms of anabolic androgenic steroid modulation of alpha(1)beta(3)gamma(2L) GABA(A) receptors.

  Neuropharmacology 20020901

• Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats.

  Neuropharmacology 20020901

• [Recurrent idiopathic stupor in a patient: responsibility of exogenous or endogenous benzodiazepines?].

  Revue neurologique 20020901

• Diazepam withdrawal-induced anxiety and place aversion in the rat: differential effects of two chronic diazepam treatment regimes.

  Behavioural pharmacology 20020901

• Temporal pole MRI abnormalities in temporal lobe epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20020901

• Pathophysiological aspects of diversity in neuronal inhibition: a new benzodiazepine pharmacology.

  Dialogues in clinical neuroscience 20020901

• Influence of different neural systems on the secretion of sex hormones in potassium deficient mice.

  Life sciences 20020816

• The heterogeneity of central benzodiazepine receptor subtypes in the human hippocampal formation, frontal cortex and cerebellum using [3H]flumazenil and zolpidem.

  Brain research. Molecular brain research 20020815

• Reversal of benzodiazepine-induced renal vasculature relaxation with flumazenil.

  European journal of pharmacology 20020802

• Midazolam induces expression of c-Fos and EGR-1 by a non-GABAergic mechanism.

  Anesthesia and analgesia 20020801

• Positron emission tomography partial volume correction: estimation and algorithms.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020801

• Gaba-benzodiazepine receptor complex in brain oxidative metabolism regulation.

  Pharmacological research 20020801

• Flumazenil in acute benzodiazepine overdose.

  The Journal of the Association of Physicians of India 20020801

• The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents.

  British journal of pharmacology 20020701

• Anesthesia-induced alterations in plasma tracer concentrations may have relevance for brain imaging studies.

  Anesthesiology 20020701

• Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701

• [The changes of bispectral index induced by administration of midazolam during propofol anesthesia].

  Masui. The Japanese journal of anesthesiology 20020701

• Tonic immobility in guinea pigs: a behavioural response for detecting an anxiolytic-like effect?

  Behavioural pharmacology 20020701

• GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.

  European journal of pharmacology 20020628

• Hypnotic effects of total aqueous extracts of Vervain hastata (Verbenaceae) in rats.

  Psychiatry and clinical neurosciences 20020601

• The effect of intravenous administration of variable-dose flumazenil after fixed-dose ketamine and midazolam in healthy cats.

  Journal of veterinary pharmacology and therapeutics 20020601

• Participation of GABAA receptors in the modulation of experimental anxiety by tachykinin agonists and antagonists in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20020601

• Cardiorespiratory effects of medetomidine-butorphanol, medetomidine-butorphanol-diazepam, and medetomidine-butorphanol-ketamine in captive red wolves (Canis rufus).

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20020601

• [Effect of flumazenil on the regional cerebral blood flow measured by [15O]-butanol PET scan and transcranial Doppler ultrasonography].

  Orvosi hetilap 20020526

• Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.

  European journal of pharmacology 20020517

• GABAA-benzodiazepine receptor complex ligands and stress-induced hyperthermia in singly housed mice.

  Pharmacology, biochemistry, and behavior 20020501

• 3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501

• Short-term effects of intravenous benzodiazepines on autonomic neurocardiac regulation in humans: a comparison between midazolam, diazepam, and lorazepam.

  Critical care medicine 20020501

• Is transient global amnesia related to endogenous benzodiazepines?

  Journal of neurology 20020501

• 125I-iomazenil-benzodiazepine receptor binding during psychological stress in rats.

  Annals of nuclear medicine 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action.

  Journal of ethnopharmacology 20020401

• Diazepam potentiates the effects of endogenous catecholamines on contractility and cyclic AMP levels in rat ventricular myocardium.

  Naunyn-Schmiedeberg's archives of pharmacology 20020401

• Free-choice ethanol consumption under the influence of GABAergic drugs in rats.

  Alcoholism, clinical and experimental research 20020401

• Partial antagonism of tiletamine-zolazepam anesthesia in cheetah.

  Journal of wildlife diseases 20020401

• A randomised crossover trial of post-operative cognitive and psychomotor recovery from benzodiazepine sedation: effects of reversal with flumazenil over a prolonged recovery period.

  British dental journal 20020323

• Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20020301

• Flumazenil vs. placebo in hepatic encephalopathy in patients with cirrhosis: a meta-analysis.

  Alimentary pharmacology & therapeutics 20020301

• Impaired benzodiazepine receptor binding in peri-lesional cortex of patients with symptomatic epilepsies studied by [(11)C]-flumazenil PET.

  European journal of neurology 20020301

• Provision of cues to signal a withdrawal US prevents the US pre-exposure effect in a diazepam-withdrawal conditioned taste aversion.

  Psychopharmacology 20020301

• The effects of neuroleptics on the GABA-induced Cl- current in rat dorsal root ganglion neurons: differences between some neuroleptics.

  British journal of pharmacology 20020301

• Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.

  Journal of psychopharmacology (Oxford, England) 20020301

• Role of benzodiazepine-GABAA receptor complex in attenuation of U-50,488H-induced analgesia and inhibition of tolerance to its analgesia by ginseng total saponin in mice.

  Life sciences 20020301

• New developments in the therapy of intoxications.

  Toxicology letters 20020227

• Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors.

  European journal of pharmacology 20020215

• Discriminative stimulus effects of benzodiazepine (BZ)(1) receptor-selective ligands in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20020201

• [(3)H]Flumazenil binding in the human hippocampal formation, frontal cortex and cerebellum detected by high-resolution phosphorimaging.

  Brain research 20020201

• Use of dynamic negative airway pressure (DNAP) to assess sedative-induced upper airway obstruction.

  Anesthesiology 20020201

• Accidental ingestion of alprazolam in 415 dogs.

  Veterinary and human toxicology 20020201

• Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography study.

  Annals of neurology 20020201

• Diazepam binding inhibitor (DBI) reduces testosterone and estradiol levels in vivo.

  Life sciences 20020201

• Nociceptin and dynorphin A(1-17) produce antianalgesia through independent systems in mice.

  Life sciences 20020118

• Binding and neuropharmacological profile of zaleplon, a novel nonbenzodiazepine sedative/hypnotic.

  European journal of pharmacology 20020102

• Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands.

  British journal of pharmacology 20020101

• Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus.

  Biological & pharmaceutical bulletin 20020101

• Flumazenil responsive ornithine transcarbamylase deficiency encephalopathy: clinical and radiographic features.

  Journal of neuroimaging : official journal of the American Society of Neuroimaging 20020101

• Mechanism of respiratory insufficiency in pure or mixed drug-induced coma involving benzodiazepines.

  Journal of toxicology. Clinical toxicology 20020101

• Midazolam sedation for upper gastrointestinal endoscopy: comparison between the states of patients in partial and complete amnesia.

  Hepato-gastroenterology 20020101

• Role of nitric oxide in benzodiazepines-induced antinociception in mice.

  Polish journal of pharmacology 20020101

• Identification of critical residues in loop E in the 5-HT3ASR binding site.

  BMC biochemistry 20020101

• [Chloral hydrate: a hypnotic best forgotten?].

  L'Encephale 20020101

• Zaleplon-induced coma and bluish-green urine: possible antidotal effect by flumazenil.

  Journal of toxicology. Clinical toxicology 20020101

• [Therapeutic management of hepatic encephalopathy].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 20020101

• TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243].

  BMC psychiatry 20020101

• Blockade of gamma-aminobutyric acid receptors does not modify the inhibiton of ethanol intake induced by Hypericum perforatum in rats.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20020101

• Cerebral blood perfusion after treatment with zolpidem and flumazenil in the baboon.

  Arzneimittel-Forschung 20020101

• Differential effects of benzodiazepines on immune responses in non-stressed and stressed animals.

  Indian journal of medical sciences 20020101

• Paradoxical reactions to benzodiazepines in intravenous sedation: a report of 2 cases and review of the literature.

  Anesthesia progress 20020101

• Flumazenil reduces the hypnotic dose of propofol in male patients under spinal anesthesia.

  Journal of anesthesia 20020101

• [Chronic liver diseases. The nihilism has gone].

  MMW Fortschritte der Medizin 20011213

• Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.

  European journal of pharmacology 20011207

• Involvement of benzodiazepine binding sites in an antiaggressive effect by 5-HT(1A) receptor activation in isolated mice.

  European journal of pharmacology 20011207

• Brain function in social anxiety disorder.

  The Psychiatric clinics of North America 20011201

• The midazolam-induced paradox phenomenon is reversible by flumazenil. Epidemiology, patient characteristics and review of the literature.

  European journal of anaesthesiology 20011201

• Chronic benzodiazepine treatment of cells expressing recombinant GABA(A) receptors uncouples allosteric binding: studies on possible mechanisms.

  Journal of neurochemistry 20011201

• Dual-[11C]tracer single-acquisition positron emission tomography studies.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201

• Delayed synaptic dysfunction of association cortices in carbon monoxide intoxication.

  Annals of neurology 20011201

• Effects of harmine on dopamine output and metabolism in rat striatum: role of monoamine oxidase-A inhibition.

  Psychopharmacology 20011201

• Effect of diazepam binding inhibitor (DBI) on the fluid intake, preference and the taste reactivity in mice.

  Behavioural brain research 20011129

• [Functional imaging (PET and SPECT) in epilepsy].

  Orvosi hetilap 20011104

• Confluence of antianalgesic action of diverse agents through brain interleukin(1beta) in mice.

  The Journal of pharmacology and experimental therapeutics 20011101

• Flumazenil improves cognitive and neuromotor emergence and attenuates shivering after halothane-, enflurane- and isoflurane-based anesthesia.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20011101

• The negative GABA(A) modulator methyl beta-carboline-3-carboxylate attenuates the behavioral effects of the positive GABA(A) modulators triazolam and pregnanolone in rhesus monkeys.

  Psychopharmacology 20011101

• Nutritional parameters modify muricidal behavior of male Wistar rats: preventive effects of amino acids and 4' Cl diazepam.

  Life sciences 20011026

• Synergistic interaction of diazepam with 3',5'-cyclic adenosine monophosphate-elevating agents on rat aortic rings.

  European journal of pharmacology 20011005

• 2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands.

  Bioorganic & medicinal chemistry 20011001

• A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder.

  Journal of affective disorders 20011001

• Biodistribution, binding specificity and metabolism of [18F]fluoroethylflumazenil in rodents.

  Nuclear medicine and biology 20011001

• [18F]Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors.

  European journal of nuclear medicine 20011001

• [Tetraplegia in the course of coma from drug intoxication].

  Annales francaises d'anesthesie et de reanimation 20011001

• Prolonged vigabatrin treatment modifies developmental changes of GABA(A)-receptor binding in young children with epilepsy.

  Epilepsia 20011001

• Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study.

  Epilepsia 20011001

• Benzodiazepines in the intensive care unit.

  Critical care clinics 20011001

• Possible mechanism of anticonvulsant effect of ketamine in mice.

  Indian journal of experimental biology 20011001

• Anxiolytic effect of Kami-Shoyo-San (TJ-24) in mice: possible mediation of neurosteroid synthesis.

  Life sciences 20010921

• Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers.

  Synapse (New York, N.Y.) 20010915

• Potency of positive gamma-aminobutyric acid(A) modulators to substitute for a midazolam discriminative stimulus in untreated monkeys does not predict potency to attenuate a flumazenil discriminative stimulus in diazepam-treated monkeys.

  The Journal of pharmacology and experimental therapeutics 20010901

• SPECT and neuropsychological performance in severe depression treated with ECT.

  Journal of affective disorders 20010901

• The effects of flumazenil, Ro 154513 and beta-CCM on the behaviour of control and stressed mice in the staircase test.

  Journal of psychopharmacology (Oxford, England) 20010901

• Dose-dependent enhancement of in vivo GABA(A)-benzodiazepine receptor binding by isoflurane.

  Anesthesiology 20010901

• Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory.

  European journal of pharmacology 20010824

• Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists.

  Brain research. Molecular brain research 20010815

• Central benzodiazepine receptors in malformations of cortical development: A quantitative study.

  Brain : a journal of neurology 20010801

• High-dose flumazenil potentiates the hypnotic activity of propofol, but not that of thiopental, in ddY mice.

  Acta anaesthesiologica Scandinavica 20010801

• The effects of benzodiazepines on human opioid receptor binding and function.

  Anesthesia and analgesia 20010801

• Changes in mACh, NMDA and GABA(A) receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections.

  Journal of neurochemistry 20010801

• Diazepam increases the hypothalamic-pituitary-adrenocortical (HPA) axis activity by a cyclic AMP-dependent mechanism.

  British journal of pharmacology 20010801

• Different types of GABA(A) receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys.

  Psychopharmacology 20010801

• Neurophysiological effects of an extract of Eschscholzia californica Cham. (Papaveraceae).

  Phytotherapy research : PTR 20010801

• Benzodiazepines protect against ethanol-induced gastric mucosal damage in vitro.

  Fundamental & clinical pharmacology 20010801

• The influences of extremely low frequency magnetic fields on clonidine-induced sleep in 2-day-old chicks.

  Journal of autonomic pharmacology 20010801

• Sleep inducing effects of propofol microinjection into the medial preoptic area are blocked by flumazenil.

  Brain research 20010727

• Availability of antidotes at acute care hospitals in Ontario.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010710

• Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships.

  Journal of medicinal chemistry 20010705

• A fluorescent receptor assay for benzodiazepines using coumarin-labeled desethylflumazenil as ligand.

  Analytical chemistry 20010701

• Hepatic Encephalopathy.

  The American journal of gastroenterology 20010701

• Case report of pallido-pyramidal disease with supplementary motor area involvement.

  Movement disorders : official journal of the Movement Disorder Society 20010701

• Disturbed benzodiazepine receptor function at the onset of temporal lobe epilepsy--lomanzenil-binding in de-novo TLE.

  Journal of neurology 20010701

• Flumazenil is a benzodiazepine receptor antagonist.

  Indian journal of physiology and pharmacology 20010701

• Relationship of flumazenil and glucose PET abnormalities to neocortical epilepsy surgery outcome.

  Neurology 20010626

• Reversal of reserpine-induced vacuous chewing movements in rats by melatonin: involvement of peripheral benzodiazepine receptors.

  Brain research 20010615

• Behavioral effects of flunitrazepam: reinforcing and discriminative stimulus effects in rhesus monkeys and prevention of withdrawal signs in pentobarbital-dependent rats.

  Drug and alcohol dependence 20010601

• Diazepam poisoning with one-month monitoring of diazepam and nordiazepam blood levels.

  Veterinary and human toxicology 20010601

• The effects of flumazenil on sleepiness, task performance and nocturnal sleep after anesthesia with midazolam.

  Psychiatry and clinical neurosciences 20010601

• A small dose of midazolam decreases the time to achieve hypnosis without delaying emergence during short-term propofol anesthesia.

  Journal of clinical anesthesia 20010601

• Interactions between LY354740, a group II metabotropic agonist and the GABA(A)-benzodiazepine receptor complex in the rat elevated plus-maze.

  Journal of psychopharmacology (Oxford, England) 20010601

• Visual event-related potentials in cirrhotic patients without overt encephalopathy: the effects of flumazenil.

  Metabolic brain disease 20010601

• Behavioral effects of agents active at the gamma-aminobutyric acid receptor complex in the staircase paradigm.

  Brain research 20010518

• Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515

• Detection and binding properties of GABA(A) receptor assembly intermediates.

  The Journal of biological chemistry 20010511

• Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT.

  Journal of neurology, neurosurgery, and psychiatry 20010501

• Absolute quantification by positron emission tomography of the endogenous ligand.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010501

• Flumazenil's reversal of myoclonic-like movements associated with midazolam in term newborns.

  Pharmacotherapy 20010501

• Modification of the effects of benzodiazepines on the exploratory behaviors of mice on a hole-board by diabetes.

  Japanese journal of pharmacology 20010501

• Melatonin enhances Th2 cell mediated immune responses: lack of sensitivity to reversal by naltrexone or benzodiazepine receptor antagonists.

  Molecular and cellular biochemistry 20010501

• Saturation assays of radioligand binding to receptors and their allosteric modulatory sites.

  Current protocols in neuroscience 20010501

• Assessment of [18F]fluoroethylflumazenil metabolites using high-performance liquid chromatography and tandem mass spectrometry.

  Journal of chromatography. B, Biomedical sciences and applications 20010415

• Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy.

  Neurology 20010410

• Zolpidem, triazolam, and diazepam decrease distress vocalizations in mouse pups: differential antagonism by flumazenil and beta-Carboline-3-carboxylate-t-butyl ester (beta-CCt).

  The Journal of pharmacology and experimental therapeutics 20010401

• Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.

  Journal of neurochemistry 20010401

• Naloxone blocks 'anxiolytic' effects of neuropeptide Y.

  Peptides 20010401

• Effects of diazepam and flumazenil on minimum alveolar concentrations for dogs anesthetized with isoflurane or a combination of isoflurane and fentanyl.

  American journal of veterinary research 20010401

• Different sensitivities to competitive inhibition of benzodiazepine receptor binding of 11C-iomazenil and 11C-flumazenil in rhesus monkey brain.

  Annals of nuclear medicine 20010401

• Comparison of N2O- and chlordiazepoxide-induced behaviors in the light/dark exploration test.

  Pharmacology, biochemistry, and behavior 20010401

• Conscious sedation with intermittent midazolam and fentanyl in electrophysiology procedures.

  Journal of interventional cardiology 20010401

• Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice.

  Journal of ethnopharmacology 20010303

• Signal transduction of flumazenil-induced preconditioning in myocytes.

  American journal of physiology. Heart and circulatory physiology 20010301

• [3H]Ro 15-1788 binding sites to brain membrane of the saltwater Mugil cephalus.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010301

• The anxiolytic effect of Sho-ju-sen, a Japanese herbal medicine, assessed by an elevated plus-maze test in mice.

  Phytotherapy research : PTR 20010301

• Mice performance on the staircase test following acute ethanol administration.

  Pharmacology, biochemistry, and behavior 20010301

• The sleep-inducing effect of ethanol microinjection into the medial preoptic area is blocked by flumazenil.

  Brain research 20010216

• Evaluation of native GABA(A) receptors containing an alpha 5 subunit.

  European journal of pharmacology 20010209

• [Preliminary report: the effect of flumazenil on the hypnotic dose of propofol in ddY mice].

  Masui. The Japanese journal of anesthesiology 20010201

• Negative inotropic effect of diazepam in isolated guinea pig heart.

  The Journal of veterinary medical science 20010201

• Effects of diazepam and beta-CCM on working memory in mice: relationships with emotional reactivity.

  Pharmacology, biochemistry, and behavior 20010201

• Anxiety-like behavior in elevated plus-maze tests in repeatedly cold-stressed mice.

  Japanese journal of pharmacology 20010201

• Triazolam discrimination in squirrel monkeys distinguishes high-efficacy agonists from other benzodiazepines and non-benzodiazepine drugs.

  Psychopharmacology 20010201

• Decreased benzodiazepine receptor density in the cerebellum of early blind human subjects.

  Brain research 20010112

• Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia.

  Brain : a journal of neurology 20010101

• The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors.

  Journal of neurochemistry 20010101

• Gender-related differences in response to placebo in benzodiazepine withdrawal: a single-blind pilot study.

  Psychopharmacology 20010101

• Relevance of experimental ischemia in cats for stroke management: a comparative reevaluation.

  Cerebrovascular diseases (Basel, Switzerland) 20010101

• Use of negatively reinforcing electrical brain stimulation to detect conventional and nonconventional anxiolytics as well as an anxiogenic drug.

  Pharmacology, biochemistry, and behavior 20010101

• A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in children before suturing.

  Emergency medicine journal : EMJ 20010101

• Flumazenil use in an emergency department: a survey.

  Journal of toxicology. Clinical toxicology 20010101

• Asymmetrical localization of benzodiazepine receptors in the human auditory cortex.

  Acta oto-laryngologica 20010101

• Estimation of regional cerebral blood flow levels in ischemia using [(15)O]water of [(11)C]flumazenil PET without arterial input function .

  Journal of computer assisted tomography 20010101

• Neuroreceptor bindings and synaptic activity in visual system of monocularly enucleated rat.

  Japanese journal of ophthalmology 20010101

• The inability of CCK to block (or CCK antagonists to substitute for) the stimulus effects of chlordiazepoxide.

  Pharmacology, biochemistry, and behavior 20010101

• GABAergic and glutamatergic modulation of exploratory behavior in the dorsomedial hypothalamus.

  Pharmacology, biochemistry, and behavior 20010101

• Voluntary self-poisoning as a cause of admission to a tertiary hospital internal medicine clinic in Piraeus, Greece within a year.

  BMC psychiatry 20010101

• Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.

  The Cochrane database of systematic reviews 20010101

• Yohimbine increases the binding potential for [11C]flumazenil in the monkey brain.

  Journal of neural transmission (Vienna, Austria : 1996) 20010101

• Effects of anxiolytic drugs on some behavioral consequences in olfactory bulbectomized rats.

  Polish journal of pharmacology 20010101

• A rapid high-pressure liquid chromatographic procedure for determination of flumazenil in plasma.

  Journal of pharmacological and toxicological methods 20010101

• Flumazenil prevents diazepam-elicited anticonvulsant action and concomitant attenuation of glutamate overflow.

  European journal of pharmacology 20001027

• The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats.

  Pharmacology, biochemistry, and behavior 20000801

• [Delayed postanoxic encephalopathy].

  Anales espanoles de pediatria 20000801

• Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines.

  Pharmacology, biochemistry, and behavior 20000601

• Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.

  Journal of medicinal chemistry 20000113

• Flumazenil challenge in social phobia.

  Depression and anxiety 20000101

• A controlled study of flumazenil-precipitated withdrawal in chronic low-dose benzodiazepine users.

  Psychopharmacology 19991101

• Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.

  Journal of medicinal chemistry 19991021

• Flumazenil antagonizes midazolam-induced airway narrowing during nasal breathing in humans.

  British journal of anaesthesia 19990501

• Midazolam-induced hyperalgesia in rats: modulation via GABA(A) receptors at supraspinal level.

  European journal of pharmacology 19990401

• The role of gamma-aminobutyric acid (GABA)-benzodiazepine neurotransmission in an animal model of methamphetamine-induced psychosis.

  [Hokkaido igaku zasshi] The Hokkaido journal of medical science 19990301

• Cerebellar granule-cell-specific GABAA receptors attenuate benzodiazepine-induced ataxia: evidence from alpha 6-subunit-deficient mice.

  The European journal of neuroscience 19990101

• [The effect of midazolam on the memory during cesarean section and the modulation by flumazenil].

  Masui. The Japanese journal of anesthesiology 19990101

• Predictive models for GABAA/benzodiazepine receptor subtypes: studies of quantitative structure-activity relationships for imidazobenzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [alphaxbeta3gamma2 (x = 1-3, 5, and 6)] via comparative molecular field analysis.

  Journal of medicinal chemistry 19981008

• Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy.

  European journal of pharmacology 19980724

• Neonatal flumazenil therapy reverses maternal diazepam.

  Acta paediatrica (Oslo, Norway : 1992) 19980201

• Possible mechanism of alprazolam-induced amnesia in mice.

  Pharmacology 19980101

• Stressful reactions and panic attacks induced by flumazenil in chronic benzodiazepine users.

  Journal of psychopharmacology (Oxford, England) 19980101

• Paradoxical reactions in children associated with midazolam use during endoscopy.

  Clinical pediatrics 19971201

• Safety and efficacy of flumazenil in reversing conscious sedation in the emergency department. Emergency Medicine Conscious Sedation Study Group.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 19971001

• Intrathecal baclofen in tetanus: four cases and a review of reported cases.

  Intensive care medicine 19970801

• Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.

  Nature 19970227

• Intrathecally administered flumazenil and PK 11195 precipitate abstinence syndrome in freely moving diazepam dependent rats.

  Drug and alcohol dependence 19961211

• The role of midazolam-induced sedation in bone marrow aspiration/trephine biopsies.

  Clinical and laboratory haematology 19961201

• [A case of convulsion induced by flumazenil].

  Masui. The Japanese journal of anesthesiology 19961001

• [Acute overdose of Zolpidem (Stilnox)].

  Schweizerische medizinische Wochenschrift 19960504

• Flumazenil-induced seizure accompanying benzodiazepine and baclofen intoxication.

  The American journal of emergency medicine 19960301

• Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.

  Molecular pharmacology 19960201

• Flumazenil associated seizure in an 11-month-old child.

  The Journal of emergency medicine 19960101

• Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.

  European journal of pharmacology 19951130

• Prolonged sedation due to accumulation of conjugated metabolites of midazolam.

  Lancet (London, England) 19950715

• Seizure after flumazenil administration in a pediatric patient.

  Pediatric emergency care 19950601

• Interaction between flumazenil and the anesthetic effects of hexobarbital in the rat.

  Brain research 19950410

• The attenuation of suppression of motility by triazolam in the conditioned fear stress task is exacerbated by ethanol in mice.

  Life sciences 19950101

• Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor.

  Journal of medicinal chemistry 19941223

• Fatal seizures after flumazenil administration in a patient with mixed overdose.

  The Annals of pharmacotherapy 19941201

• Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil.

  British journal of pharmacology 19941201

• Gender differences in diazepam withdrawal syndrome in mice.

  Pharmacology & toxicology 19941201

• Benzodiazepine receptor mediation of the anxiolytic-like effect of (-)-nicotine in mice.

  Pharmacology, biochemistry, and behavior 19941101

• Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice.

  Psychopharmacology 19940601

• Seizure after reversal of benzodiazepine treatment with flumazenil: a report of two cases.

  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 19940601

• Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.

  The Journal of pharmacology and experimental therapeutics 19940401

• Flumazenil induces seizures and death in mixed cocaine-diazepam intoxications.

  Annals of emergency medicine 19940301

• Evaluation of flumazenil for reversing the effects of midazolam-induced conscious sedation or general anesthesia.

  Southern medical journal 19931101

• Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence.

  Neuropharmacology 19930901

• Temporary abolition of seizure activity by flumazenil in a case of valproate-induced non-convulsive status epilepticus.

  Seizure 19930901

• Flumazenil reverses diazepam-induced neonatal apnoea and hypotonia.

  European journal of pediatrics 19930501

• The effect of oral flumazenil on interictal epileptic activity: results of a double-blind, placebo-controlled study.

  Epilepsy research 19930501

• Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance.

  Pharmacological research 19930101

• Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.

  Critical care medicine 19921201

• Changes in benzodiazepine-receptor activity modify morphine withdrawal syndrome in mice.

  Drug and alcohol dependence 19920801

• [Effects of agonists and antagonists of benzodiazepine, GABA and NMDA receptors, on caffeine-induced seizures in mice].

  Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology 19920801

• Effects of flumazenil on intravenous lidocaine-induced convulsions and anticonvulsant property of diazepam in rats.

  Anesthesia and analgesia 19920701

• Flumazenil counteracts intrathecal baclofen-induced central nervous system depression in tetanus.

  Anesthesiology 19920601

• Flumazenil in mixed benzodiazepine/tricyclic antidepressant overdose: a placebo-controlled study in the dog.

  The American journal of emergency medicine 19920501

• [Extreme duration of action of diazepam as a cause of respiratory insufficiency in a female geriatric patient].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 19920401

• Reversal of central benzodiazepine effects by flumazenil after conscious sedation produced by intravenous diazepam. The Flumazenil in Intravenous Conscious Sedation with Diazepam Multicenter Study Group I.

  Clinical therapeutics 19920101

• Reversal of central benzodiazepine effects by flumazenil after intravenous conscious sedation with diazepam and opioids: report of a double-blind multicenter study. The Flumazenil in Intravenous Conscious Sedation with Diazepam Multicenter Study Group II.

  Clinical therapeutics 19920101

• [Paradoxical reaction to midazolam after its use as a sedative in regional anesthesia].

  Revista espanola de anestesiologia y reanimacion 19920101

• Relative anticonvulsant effects of GABAmimetic and GABA modulatory agents.

  Epilepsia 19920101

• Local anesthetic-induced toxicity may be modified by low doses of flumazenil.

  Life sciences 19920101

• Oral self-administration of triazolam, diazepam and ethanol in the baboon: drug reinforcement and benzodiazepine physical dependence.

  Psychopharmacology 19920101

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• Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure.

  The New England journal of medicine 19910815

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  Human & experimental toxicology 19910701

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  British journal of anaesthesia 19900801

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  British journal of anaesthesia 19900601

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  European journal of pharmacology 19890117

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  Life sciences 19890101

• Enhancement of learning and memory in mice by a benzodiazepine antagonist.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19880801

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• Benzodiazepines, but not beta carbolines, limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture.

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• Allosteric modulation by benzodiazepine receptor ligands of the GABAA receptor channel expressed in Xenopus oocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 19880101

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  Neurotoxicology and teratology 19880101

• The effects of chronic antidepressant treatment in an animal model of anxiety.

  Psychopharmacology 19880101

• Antagonism of diazepam-induced sedative effects by Ro15-1788 in patients after surgery under lumbar epidural block. A double-blind placebo-controlled investigation of efficacy and safety.

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• Stupor and affective state: alleviation of psychomotor disturbances by lorazepam and recurrence of symptoms after Ro 15-1788.

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• Coincidence of seizure susceptibility to caffeine and to the benzodiazepine inverse agonist, DMCM, in SWR and CBA inbred mice.

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• Ro 15-1788 for postoperative recovery. A randomised clinical trial in patients undergoing minor surgical procedures under midazolam anaesthesia.

  Anaesthesia 19861001

• Clinical evaluation of a specific benzodiazepine antagonist (RO 15-1788). Studies in elderly patients after regional anaesthesia under benzodiazepine sedation.

  British journal of anaesthesia 19860901

• Benzodiazepine antagonist, CGS-8216, in diazepam- or pentobarbital-dependent and non-dependent rats.

  Drug and alcohol dependence 19860701

• Diazepam-induced decrease in histamine turnover in mouse brain.

  European journal of pharmacology 19860527

• Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.

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  Pharmacology 19860101

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• Anticonvulsant and antipunishment effects of toluene.

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  European journal of pharmacology 19840127

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  Psychopharmacology 19840101

• Enhancement of GABA binding by benzodiazepines and related anxiolytics.

  European journal of pharmacology 19830506

• Reversal of the muscle relaxant effect of diazepam by the specific benzodiazepine antagonist Ro 15-1788: an electromyographic study in morphine model of muscular rigidity in rats.

  Life sciences 19830101

• Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines.

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• Benzodiazepine antagonist Ro 15-1788: neurological and behavioral effects.

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