79416-27-6 | 5-Aminolevulinic acid methyl ester, HCl

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$8.00	$5.00
250mg	98%	in stock	$9.00	$6.00
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$36.00	$25.00
10g	98%	in stock	$70.00	$49.00
25g	98%	in stock	$175.00	$122.00
100g	98%	in stock	$665.00	$466.00

Description

• Catalog Number: AB48145
• Chemical Name: 5-Aminolevulinic acid methyl ester, HCl
• CAS Number: 79416-27-6
• Molecular Formula: C6H12ClNO3
• Molecular Weight: 181.6174
• MDL Number: MFCD00012868
• SMILES: NCC(=O)CCC(=O)OC.Cl

Computed Properties

• Complexity: 133
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5

Literature

• Comparison of the uptake of 5-aminolevulinic acid and its methyl ester in keratinocytes and skin.

  Naunyn-Schmiedeberg's archives of pharmacology 20121001

• [Fluorescence diagnosis of non-melanoma skin cancer].

  Orvosi hetilap 20120826

• δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones.

  Naunyn-Schmiedeberg's archives of pharmacology 20111201

• [Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication].

  Enfermedades infecciosas y microbiologia clinica 20111001

• Optimization of photodynamic therapy response by survivin gene knockdown in human metastatic breast cancer T47D cells.

  Journal of photochemistry and photobiology. B, Biology 20110902

• Increased cutaneous oxygen availability by topical application of hydrogen peroxide cream enhances the photodynamic reaction to topical 5-aminolevulinic acid-methyl ester.

  Archives of dermatological research 20110501

• Treatment with 5-aminolaevulinic acid methylester is less painful than treatment with 5-aminolaevulinic acid nanoemulsion in topical photodynamic therapy for actinic keratosis.

  Dermatology (Basel, Switzerland) 20110101

• Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy.

  Photodiagnosis and photodynamic therapy 20101201

• Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema.

  Pharmaceutical research 20101001

• Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancers.

  Journal of cancer research and clinical oncology 20100801

• [Erosive pustulosis on the scalp following dynamic phototherapy].

  Annales de dermatologie et de venereologie 20100101

• Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema.

  The British journal of dermatology 20091101

• New aspects in photodynamic therapy of actinic keratoses.

  Journal of photochemistry and photobiology. B, Biology 20090904

• Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy.

  Journal of photochemistry and photobiology. B, Biology 20090904

• Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy.

  Dermatology (Basel, Switzerland) 20090101

• Images in clinical medicine. Fluorescence diagnosis of subclinical actinic keratoses.

  The New England journal of medicine 20080508

• Identification of tetrapyrrole compounds excreted by Rhodobacter sphaeroides and sources of the methyl hydrogens of bacteriochlorophyll a biosynthesized by R. sphaeroides, based on 13C-NMR spectral analysis of coproporphyrin III tetramethyl ester.

  Chemical & pharmaceutical bulletin 20070701

• Topical photodynamic therapy of actinic keratosis in renal transplant recipients.

  Transplantation proceedings 20070101

• Photodynamic therapy using a methyl ester of 5-aminolevulinic acid in recurrent Paget's disease of the vulva: a pilot study.

  Gynecologic oncology 20061101

• A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.

  International journal of oncology 20061001

• The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid.

  Journal of photochemistry and photobiology. B, Biology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• The temperature dependence of porphyrin production in Propionibacterium acnes after incubation with 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA).

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060101

• Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester.

  The Journal of investigative dermatology 20051101

• Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester.

  Photochemistry and photobiology 20050101

• Transdermal delivery from a lipid sponge phase--iontophoretic and passive transport in vitro of 5-aminolevulinic acid and its methyl ester.

  Journal of controlled release : official journal of the Controlled Release Society 20041124

• Iontophoretic delivery of 5-aminolevulinic acid and its methyl ester using a carbopol gel as vehicle.

  Journal of controlled release : official journal of the Controlled Release Society 20040723

• Allergic contact dermatitis to 5-aminolaevulinic acid methylester but not to 5-aminolaevulinic acid after photodynamic therapy.

  The British journal of dermatology 20040101

• A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer.

  International journal of oncology 20030201

• Comparative in vitro percutaneous penetration of 5-aminolevulinic acid and two of its esters through excised hairless mouse skin.

  Lasers in surgery and medicine 20030101

• The role of light in the treatment of non-melanoma skin cancer using methyl aminolevulinate.

  The Journal of dermatological treatment 20030101

• Clinical efficacy of methyl aminolevulinate (Metvix) photodynamic therapy.

  The Journal of dermatological treatment 20030101

• Methyl aminolevulinate (Metvix) photodynamic therapy - practical pearls.

  The Journal of dermatological treatment 20030101

• Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice.

  Biochemical and biophysical research communications 20020927

• Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice.

  Archives of dermatological research 20020701

• Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester.

  Journal of photochemistry and photobiology. B, Biology 20020501

• Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon.

  British journal of cancer 20011101

• 5-Aminolaevulinic acid methyl ester transport on amino acid carriers in a human colon adenocarcinoma cell line.

  Photochemistry and photobiology 20010201