80-77-3 | Chlormezanone

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$12.00	$9.00
1g	98%	in stock	$34.00	$24.00

Description

• Catalog Number: AC34921
• Chemical Name: Chlormezanone
• CAS Number: 80-77-3
• Molecular Formula: C11H12ClNO3S
• Molecular Weight: 273.7359
• MDL Number: MFCD00143951
• SMILES: CN1C(=O)CCS(=O)(=O)C1c1ccc(cc1)Cl

Computed Properties

• Complexity: 395
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 1.1

Literature

• Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

  Toxicology and applied pharmacology 20170301

• [Determination of chlormezanone in serum by gas chromatography].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20120501

• The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation.

  International journal of hepatology 20120101

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Anesthetic management for emergent Cesarean section in a patient with toxic epidermal necrolysis -A case report-.

  Korean journal of anesthesiology 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Flupirtine in pain management: pharmacological properties and clinical use.

  CNS drugs 20101001

• Toxic epidermal necrolysis and Stevens-Johnson syndrome.

  Orphanet journal of rare diseases 20100101

• [Retrospective analysis of the combined therapy of terazosin with chlormezanone for chronic prostatitis/chronic pelvic pain syndrome].

  Zhonghua nan ke xue = National journal of andrology 20090801

• Fixed drug eruption resulting from fluconazole use: a case report.

  Journal of medical case reports 20090101

• Adjuvant laser acupuncture in the treatment of whiplash injuries: a prospective, randomized placebo-controlled trial.

  Wiener klinische Wochenschrift 20060301

• Biology and therapy of fibromyalgia. New therapies in fibromyalgia.

  Arthritis research & therapy 20060101

• Investigations of interactions of chlormezanone racemate and its enantiomers on human keratinocytes and human leucoytes in vitro.

  Skin pharmacology and physiology 20050101

• [New findings on the synthesis of the centrally acting muscle relaxant chlormezanone and its resolution of a gram scale using a Chiralcel OD column].

  Die Pharmazie 20030201

• Stimulatory effects of chlorzoxazone, a centrally acting muscle relaxant, on large conductance calcium-activated potassium channels in pituitary GH3 cells.

  Brain research 20030103

• [Acute confusional syndrome associated to chlormezanone].

  Revista medica de Chile 20021101

• [Acute confusional syndrome associated to Chlormezanone use].

  Revista medica de Chile 20020601

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• [Retrospective of national pharmacovigilance surveys on drug-induced bullous, vesicular eruptions: methods and results ].

  Therapie 20020101

• Risk of serious skin disorders among users of oral antifungals: a population-based study.

  BMC dermatology 20020101

• [Lyell syndrome in Senegal: responsibility of thiacetazone].

  Annales de dermatologie et de venereologie 20011201

• [Important pharmaceutical-chemical characteristics of the central muscle relaxant chlormezanone].

  Die Pharmazie 20000401

• [Cleavage and biotransformation of the central muscle relaxant chlormezanone].

  Die Pharmazie 19980901

• Chlormezanone-induced fulminant hepatitis in a pregnant woman: successful delivery and liver transplantation.

  Journal of gastroenterology and hepatology 19920101

• [Pharmacokinetics of chlormezanone in healthy volunteers].

  Therapie 19900101

• [Drug-induced hepatitis with cholestasis following therapy with chlormezanone].

  Zeitschrift fur Gastroenterologie 19851201

• Drug-related gustatory disorders.

  The Annals of otology, rhinology, and laryngology 19780101