802904-66-1 | Azd1981

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$7.00	$5.00
5mg	99%	in stock	$10.00	$7.00
10mg	99%	in stock	$14.00	$10.00
50mg	99%	in stock	$37.00	$26.00
100mg	99%	in stock	$48.00	$34.00
250mg	99%	in stock	$84.00	$59.00

Description

• Catalog Number: AH51148
• Chemical Name: Azd1981
• CAS Number: 802904-66-1
• Molecular Formula: C19H17ClN2O3S
• Molecular Weight: 388.86788
• MDL Number: MFCD26936340
• SMILES: CC(=O)Nc1cccc2c1c(Sc1ccc(cc1)Cl)c(n2CC(=O)O)C

Computed Properties

• Complexity: 527
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 4

Literature

• Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.

  Molecular pharmacology 20160501

• Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.

  Nature reviews. Drug discovery 20140601

• Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981.

  Bioorganic & medicinal chemistry letters 20111101