81265-93-2 | 5'-O-DMT-2'-O-TBDMS-N6-Bz-adenosine

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$18.00	$12.00
250mg	95%	in stock	$28.00	$19.00
1g	95%	in stock	$28.00	$19.00
5g	95%	in stock	$129.00	$90.00
25g	95%	in stock	$475.00	$333.00

Description

• Catalog Number: AC38468
• Chemical Name: 5'-O-DMT-2'-O-TBDMS-N6-Bz-adenosine
• CAS Number: 81265-93-2
• Molecular Formula: C44H49N5O7Si
• Molecular Weight: 787.9747
• MDL Number: MFCD00080294
• SMILES: COc1ccc(cc1)C(c1ccc(cc1)OC)(c1ccccc1)OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O[Si](C(C)(C)C)(C)C)n1cnc2c1ncnc2NC(=O)c1ccccc1

Computed Properties

• Complexity: 1250
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 57
• Hydrogen Bond Acceptor Count: 10
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 14

Upstream Synthesis Route

The 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine compound is a versatile building block used in chemical synthesis for the modification of nucleosides and nucleotides. This unique molecule contains multiple protective groups, including DMT (4,4'-Dimethoxytrityl), TBDMS (tert-butyldimethylsilyl), and benzoyl (Bz), which provide selective reactivity in organic reactions.One important application of 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is in the synthesis of modified oligonucleotides for research and therapeutic purposes. This compound serves as a key intermediate for the introduction of various functional groups or labels onto the adenosine nucleoside, allowing for the creation of custom-designed nucleic acid analogs with specific properties.Furthermore, the presence of multiple protection groups in 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine enables sequential deprotection and selective reactions, facilitating the controlled assembly of complex nucleotide sequences. This precision in chemical manipulation is essential for the synthesis of oligonucleotide-based therapeutics, diagnostic probes, and molecular tools used in biotechnology and medicine.Overall, 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine plays a crucial role in the field of chemical synthesis by offering chemists a strategic tool for the modification and functionalization of nucleosides, leading to the development of novel nucleotide analogs with diverse applications in biotechnology and biomedical research.