82009-34-5 | (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$46.00	$32.00
1g	95%	in stock	$109.00	$76.00
5g	95%	in stock	$343.00	$240.00
25g	95%	in stock	$1,505.00	$1,054.00

Description

• Catalog Number: AB47642
• Chemical Name: (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
• CAS Number: 82009-34-5
• Molecular Formula: C16H26N2O5S
• Molecular Weight: 358.4530
• MDL Number: MFCD00867379
• SMILES: OC(=O)[C@@H](CSCCCC/C=C(/C(=O)O)\NC(=O)[C@H]1CC1(C)C)N

Computed Properties

• Complexity: 519
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 11
• XLogP3: -1

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• The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem.

  Journal of the American Society of Nephrology : JASN 19901101

• Meropenem: evidence of lack of proconvulsive tendency in mice.

  The Journal of antimicrobial chemotherapy 19890901

• [Seizure and tremor occurring in acute leukemia patients treated with imipenem/cilastatin].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19890301

• Neurotoxicity of beta-lactam antibiotics. Experimental kinetic and neurophysiological studies.

  Scandinavian journal of infectious diseases. Supplementum 19880101

• Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids.

  Journal of medicinal chemistry 19870601

• Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.

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• Imipenem-cilastatin sodium, a broad-spectrum carbapenem antibiotic combination.

  Clinical pharmacy 19860901

• Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin.

  The American journal of medicine 19850607

• Thienamycin: development of imipenen-cilastatin.

  The Journal of antimicrobial chemotherapy 19831201