823-40-5 | 2,6-Diaminotoluene

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$15.00	$10.00
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$25.00	$17.00
10g	98%	in stock	$30.00	$21.00
25g	98%	in stock	$49.00	$34.00
100g	98%	in stock	$137.00	$96.00
500g	98%	in stock	$448.00	$314.00

Description

• Catalog Number: AD99707
• Chemical Name: 2,6-Diaminotoluene
• CAS Number: 823-40-5
• Molecular Formula: C7H10N2
• Molecular Weight: 122.1677
• MDL Number: MFCD00007800
• SMILES: Nc1cccc(c1C)N
• NSC Number: 147490

Computed Properties

• Complexity: 82.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 0.9

Literature

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  The Journal of toxicological sciences 20151201

• Air exposure assessment of TDI and biological monitoring of TDA in urine in workers in polyurethane foam industry.

  Occupational and environmental medicine 20120201

• Biological monitoring as a valid tool to assess occupational exposure to mixtures of 2,4-:2,6-toluene diisocyanate.

  La Medicina del lavoro 20120101

• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats.

  Journal of toxicologic pathology 20111201

• Environmental isocyanate-induced asthma: morphologic and pathogenetic aspects of an increasing occupational disease.

  International journal of environmental research and public health 20110901

• Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies.

  Journal of occupational medicine and toxicology (London, England) 20110101

• New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats.

  Cancer informatics 20110101

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  Mutation research 20100930

• Determination of aromatic amines in aqueous extracts of polyurethane foam using hydrophilic interaction liquid chromatography and mass spectrometry.

  Analytica chimica acta 20100923

• Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers.

  Toxicological sciences : an official journal of the Society of Toxicology 20100301

• Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate.

  Mutation research 20080731

• Biological monitoring of TDI-derived amines in polyurethane foam production.

  Occupational medicine (Oxford, England) 20070901

• Removal of dinitrotoluenes from water via reduction with iron and peroxidase-catalyzed oxidative polymerization: a comparison between Arthromyces ramosus peroxidase and soybean peroxidase.

  Chemosphere 20070401

• Differences in gene expression profiles in the liver between carcinogenic and non-carcinogenic isomers of compounds given to rats in a 28-day repeat-dose toxicity study.

  Toxicology and applied pharmacology 20061215

• Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.

  Mutation research 20060919

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Ab initio MO analysis of the excited electronic states of high-spin quintet 2-methylphenylene-1,3-dinitrene.

  Angewandte Chemie (International ed. in English) 20060327

• Risk evaluation of occupational exposure to methylene dianiline and toluene diamine in polyurethane foam.

  Human & experimental toxicology 20051201

• Upper reference limits for biomarkers of exposure to aromatic diisocyanates.

  International archives of occupational and environmental health 20050801

• Improvement in the GC-MS method for determining urinary toluene-diamine and its application to the biological monitoring of workers exposed to toluene-diisocyanate.

  International archives of occupational and environmental health 20050701

• Biological monitoring of exposure to toluene diisocyanate.

  Scandinavian journal of work, environment & health 20041001

• Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions.

  Environmental science & technology 20040215

• [Assessment of the emission of volatile organic compounds from polyurethane foams].

  Roczniki Panstwowego Zakladu Higieny 20040101

• Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

• Biological monitoring of aromatic diisocyanates in workers exposed to thermal degradation products of polyurethanes.

  Journal of environmental monitoring : JEM 20021001

• LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate.

  Toxicology letters 20020805

• Organic analysis by ion chromatography. 1. Determination of aromatic amines and aromatic diisocyanates by cation-exchange chromatography with amperometric detection.

  Journal of chromatography. A 20020517

• Exposure to 2,4- and 2,6-toluene diisocyanate (TDI) during production of flexible foam: determination of airborne TDI and urinary 2,4- and 2,6-toluenediamine (TDA).

  The Analyst 20010701

• Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.

  Toxicology and applied pharmacology 19960701

• Comparison of DNA binding between the carcinogen 2,6-dinitrotoluene and its noncarcinogenic analog 2,6-diaminotoluene.

  Mutation research 19930201