82473-24-3 | Chapso

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$42.00	$30.00
1g	95%	in stock	$50.00	$35.00
5g	95%	in stock	$171.00	$120.00
25g	95%	in stock	$605.00	$423.00

Description

• Catalog Number: AI56770
• Chemical Name: Chapso
• CAS Number: 82473-24-3
• Molecular Formula: C32H58N2O8S
• Molecular Weight: 630.8765
• MDL Number: MFCD00081079
• SMILES: OC(CS(=O)(=O)[O-])C[N+](CCCNC(=O)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)[C@@H](O)C[C@H]1[C@H]2[C@H](O)C[C@H]2[C@]1(C)CC[C@H](C2)O)C)(C)C

Computed Properties

• Complexity: 1070
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 11
• Heavy Atom Count: 43
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 11
• Undefined Atom Stereocenter Count: 1
• XLogP3: 1.9

Literature

• High-throughput crystallization of membrane proteins using the lipidic bicelle method.

  Journal of visualized experiments : JoVE 20120109

• Interactions of hemin with model erythrocyte membranes.

  The journal of physical chemistry. B 20100408

• Phosphoinositides suppress gamma-secretase in both the detergent-soluble and -insoluble states.

  The Journal of biological chemistry 20080711

• Biochemical properties of endogenous presenilin 1 and presenilin 2 in cultured human B-lymphocytes.

  Clinical chemistry and laboratory medicine 20070101

• 3-O-alkyl-D-glucose derivatives induce fruit bodies of Pleurotus ostreatus.

  Mycological research 20050301

• Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.

  The Journal of biological chemistry 20041203

• Conserved residues within the putative active site of gamma-secretase differentially influence enzyme activity and inhibitor binding.

  Journal of neurochemistry 20040901

• Effect of membrane perturbants on the activity and phase distribution of inositol phosphorylceramide synthase; development of a novel assay.

  Biochemistry 20040706

• Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells.

  Alzheimer disease and associated disorders 20040101

• Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin.

  The Journal of biological chemistry 20030926

• Use of chiral zwitterionic surfactants for enantiomeric resolutions by capillary electrophoresis.

  Electrophoresis 20030801

• Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.

  Biochemistry 20010727