82795-51-5 | D-Homophenylalanine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$29.00	$20.00
10g	98%	in stock	$33.00	$23.00
100g	98%	in stock	$259.00	$182.00

Description

• Catalog Number: AB42744
• Chemical Name: D-Homophenylalanine
• CAS Number: 82795-51-5
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.2157
• MDL Number: MFCD00063091
• SMILES: N[C@@H](C(=O)O)CCc1ccccc1

Computed Properties

• Complexity: 164
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: -1.2

Literature

• Protease-activated drug development.

  Theranostics 20120101

• In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

  PLoS neglected tropical diseases 20100901

• New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

  Bioorganic & medicinal chemistry 20100415

• In vitro mutasynthesis of lantibiotic analogues containing nonproteinogenic amino acids.

  Journal of the American Chemical Society 20090902

• Synthesis and immunosuppressive activity of cyclolinopeptide A analogues containing homophenylalanine.

  European journal of medicinal chemistry 20090901

• Lyngbyazothrins A-D, antimicrobial cyclic undecapeptides from the cultured Cyanobacterium lyngbya sp.

  Journal of natural products 20090801

• Effective synthesis of optically active trifluoromethyldiazirinyl homophenylalanine and aroylalanine derivatives with the Friedel-Crafts reaction in triflic acid.

  Bioscience, biotechnology, and biochemistry 20090601

• Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial genera.

  BMC evolutionary biology 20080101

• Non-natural and photo-reactive amino acids as biochemical probes of immune function.

  PloS one 20080101

• Highly potent and selective substrate analogue factor Xa inhibitors containing D-homophenylalanine analogues as P3 residue: part 2.

  ChemMedChem 20070701

• Conformational analysis of endomorphin-2 analogs with phenylalanine mimics by NMR and molecular modeling.

  Bioorganic & medicinal chemistry 20070515

• Structures of pahayokolides A and B, cyclic peptides from a Lyngbya sp.

  Journal of natural products 20070501

• Quantification of free amino acids and dipeptides using isotope dilution liquid chromatography and electrospray ionization tandem mass spectrometry.

  Amino acids 20070201

• Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity.

  ChemMedChem 20060801

• Opioid receptor binding and antinociceptive activity of the analogues of endomorphin-2 and morphiceptin with phenylalanine mimics in the position 3 or 4.

  Bioorganic & medicinal chemistry letters 20060715

• Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.

  The Biochemical journal 20051215

• Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.

  Combinatorial chemistry & high throughput screening 20050601

• Potent and selective proline derived dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20041018

• The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling.

  The Journal of biological chemistry 20031219

• Enantioseparation of chiral aromatic amino acids by capillary electrophoresis in neutral and charged cyclodextrin selector modes.

  Electrophoresis 20021201

• Structure-activity relationships of neuropeptide FF: role of C-terminal regions.

  Peptides 20010901