83280-65-3 | 2-acetylfuro-1,4-naphthoquinone

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$35.00	$24.00
5mg	95%	in stock	$52.00	$36.00
10mg	95%	in stock	$65.00	$45.00
25mg	95%	in stock	$106.00	$74.00
100mg	95%	in stock	$169.00	$118.00
250mg	95%	in stock	$258.00	$180.00
1g	95%	in stock	$643.00	$450.00
5g	95%	in stock	$2,246.00	$1,572.00

Description

• Catalog Number: AH51034
• Chemical Name: 2-acetylfuro-1,4-naphthoquinone
• CAS Number: 83280-65-3
• Molecular Formula: C14H8O4
• Molecular Weight: 240.2109
• MDL Number: MFCD28155270
• SMILES: CC(=O)c1cc2c(o1)C(=O)c1c(C2=O)cccc1

Computed Properties

• Complexity: 414
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• XLogP3: 2.3

Literature

• Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin.

  Cancer medicine 20160601

• Suppression of cancer relapse and metastasis by inhibiting cancer stemness.

  Proceedings of the National Academy of Sciences of the United States of America 20150210

• Synthesis and structure-activity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular generation of superoxide.

  Journal of medicinal chemistry 20120823

• Antileishmanial, antitrypanosomal, and cytotoxic screening of ethnopharmacologically selected Peruvian plants.

  Parasitology research 20120401

• Antiprotozoal activities of some constituents of Markhamia tomentosa (Bignoniaceae).

  Annals of tropical medicine and parasitology 20100701

• Semisynthesis and antitumoral activity of 2-acetylfuranonaphthoquinone and other naphthoquinone derivatives from lapachol.

  Bioorganic & medicinal chemistry letters 20081015