837-52-5 | 7-Chloro-4-piperazin-1-yl-quinoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$18.00	$12.00
1g	95%	in stock	$28.00	$19.00
5g	95%	in stock	$99.00	$69.00
10g	95%	in stock	$163.00	$114.00
25g	95%	in stock	$348.00	$244.00
100g	95%	in stock	$1,344.00	$941.00

Description

• Catalog Number: AB70100
• Chemical Name: 7-Chloro-4-piperazin-1-yl-quinoline
• CAS Number: 837-52-5
• Molecular Formula: C13H14ClN3
• Molecular Weight: 247.7234
• MDL Number: MFCD01476123
• SMILES: Clc1ccc2c(c1)nccc2N1CCNCC1

Computed Properties

• Complexity: 255
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.4

Literature

• Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.

  ACS medicinal chemistry letters 20131010

• 7-Chloro-4-(piperazin-1-yl)quinoline.

  Acta crystallographica. Section E, Structure reports online 20120501

• Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.

  Journal of medicinal chemistry 20110526

• Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.

  Bioorganic & medicinal chemistry letters 20110515

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Quinolines and structurally related heterocycles as antimalarials.

  European journal of medicinal chemistry 20100801

• Synthesis of novel hybrid molecules from precursors with known antiparasitic activity.

  Molecules (Basel, Switzerland) 20090409

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501