841-77-0 | 1-Benzhydrylpiperazine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$15.00	$10.00
5g	97%	in stock	$16.00	$11.00
25g	97%	in stock	$29.00	$20.00
100g	97%	in stock	$78.00	$54.00
250g	97%	in stock	$182.00	$127.00
1kg	97%	in stock	$537.00	$376.00

Description

• Catalog Number: AB70921
• Chemical Name: 1-Benzhydrylpiperazine
• CAS Number: 841-77-0
• Molecular Formula: C17H20N2
• Molecular Weight: 252.3541
• MDL Number: MFCD00038379
• SMILES: N1CCN(CC1)C(c1ccccc1)c1ccccc1
• NSC Number: 35536

Computed Properties

• Complexity: 230
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 2.8

Literature

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  Journal of pain and symptom management 20120301

• (E)-1-(4-Benzhydrylpiperazin-1-yl)-3-(2-eth-oxy-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20111201

• Asymmetric synthesis and biological evaluation of N-cyclohexyl-4-[1-(2,4-dichlorophenyl)-1-(p-tolyl)methyl]piperazine-1-carboxamide as hCB1 receptor antagonists.

  European journal of medicinal chemistry 20111101

• (E)-1-(4-Benzhydrylpiperazin-1-yl)-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol monosolvate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Quantification of cyclizine and norcyclizine in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110315

• Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors.

  Chemical & pharmaceutical bulletin 20110101

• Alleviation of brain hypoperfusion after preventative treatment with lomerizine in an elderly migraineur with aura.

  International journal of molecular imaging 20110101

• Nonpeptidic delta (delta) opioid agonists and antagonists of the diarylmethylpiperazine class: what have we learned?

  Topics in current chemistry 20110101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.

  European journal of medicinal chemistry 20100301

• Apoptosis of human Burkitt's lymphoma cells induced by 2-N,N-diethylaminocarbonyloxymethyl-1-diphenylmethyl-4-(3,4,5-trimethoxybenzoyl) piperazine hydrochloride (PMS-1077).

  Archives of pharmacal research 20091201

• Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines.

  European journal of medicinal chemistry 20090301

• Synthesis and evaluation of 1-benzhydryl-sulfonyl-piperazine derivatives as inhibitors of tumor growth and tumor angiogenesis of mouse ehrlich ascites tumor in vivo.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901

• Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine.

  Inorganic chemistry 20080804

• Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.

  Bioorganic & medicinal chemistry 20080401

• 1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.

  Acta crystallographica. Section E, Structure reports online 20080201

• [Piperazines as model substrate for oxidations].

  Die Pharmazie 20061001

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• A new calcium channel antagonist, lomerizine, alleviates secondary retinal ganglion cell death after optic nerve injury in the rat.

  Current eye research 20060301

• DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats.

  The Journal of pharmacology and experimental therapeutics 20051101

• Hydroxyzine and metabolites as a source of interference in carbamazepine particle-enhanced turbidimetric inhibition immunoassay (PETINIA).

  Therapeutic drug monitoring 20050801

• [Preparation and physico-chemical properties of alkyl esters of 2-, 3-, 4-(2-hydroxy-3-[4-diphenylmethyl) piperazine-1-yl] propoxy) phenylcarbamide].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20021101

• Non-peptide opioid receptor ligands - recent advances. Part I - agonists.

  Current medicinal chemistry 20020901

• Biotransformation of cyclizine in greyhounds. 1: Identification and analysis of cyclizine and some basic metabolites in canine urine by gas chromatography-mass spectrometry.

  Xenobiotica; the fate of foreign compounds in biological systems 20020901

• Biotransformation of cyclizine in greyhounds. 2: N(1)-dealkylation and identification of some neutral and phenolic metabolites in canine urine by gas chromatography-mass spectrometry.

  Xenobiotica; the fate of foreign compounds in biological systems 20020901