84348-38-9 | (2S)-1-[(tert-butoxy)carbonyl]-4-methylidenepyrrolidine-2-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$48.00	$34.00
25g	98%	in stock	$86.00	$61.00

Description

• Catalog Number: AB52370
• Chemical Name: (2S)-1-[(tert-butoxy)carbonyl]-4-methylidenepyrrolidine-2-carboxylic acid
• CAS Number: 84348-38-9
• Molecular Formula: C11H17NO4
• Molecular Weight: 227.257
• MDL Number: MFCD01861787
• SMILES: O=C(N1CC(=C)C[C@H]1C(=O)O)OC(C)(C)C

Computed Properties

• Complexity: 329
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 1

Upstream Synthesis Route

N-tert-Butoxycarbonyl-4-methylene-L-proline is a valuable reagent in chemical synthesis due to its unique structural features and versatile reactivity. This compound serves as a pivotal building block in the preparation of various organic molecules, particularly in the field of peptide and pharmaceutical synthesis. By virtue of its N-protecting group and α, β-unsaturated nature, N-tert-Butoxycarbonyl-4-methylene-L-proline can participate in a wide range of transformations, such as Michael additions, cyclizations, and cross-coupling reactions. Its strategic placement within a molecule allows for selective functionalization and manipulation of peptide sequences, enabling the synthesis of complex and biologically active compounds. Furthermore, the presence of the tert-butoxycarbonyl group offers protection to the amino functionality, facilitating sequential synthesis steps and enhancing overall synthetic efficiency. With its utility in peptide chemistry and drug discovery, N-tert-Butoxycarbonyl-4-methylene-L-proline is an indispensable tool for organic chemists seeking to access diverse structures and novel chemical entities.