84418-43-9 | Fmoc-nh2

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$14.00	$10.00
25g	98%	in stock	$23.00	$17.00
100g	98%	in stock	$37.00	$26.00

Description

• Catalog Number: AB70335
• Chemical Name: Fmoc-nh2
• CAS Number: 84418-43-9
• Molecular Formula: C15H13NO2
• Molecular Weight: 239.26922
• MDL Number: MFCD00237376
• SMILES: NC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 296
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 2.7

Literature

• Synthetic procedure for N-Fmoc amino acyl-N-sulfanylethylaniline linker as crypto-peptide thioester precursor with application to native chemical ligation.

  The Journal of organic chemistry 20120817

• Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation.

  European biophysics journal : EBJ 20120201

• Soluble peptidyl phosphoranes for metal-free, stereoselective ligations in organic and aqueous solution.

  Organic letters 20120106

• Improved synthesis strategy for peptide nucleic acids (PNA) appropriate for cell-specific fluorescence imaging.

  International journal of medical sciences 20120101

• Development of a novel biosensor using cationic antimicrobial Peptide and nickel phthalocyanine ultrathin films for electrochemical detection of dopamine.

  International journal of analytical chemistry 20120101

• Enzymatic self-assembly of nanostructures for theranostics.

  Theranostics 20120101

• Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancer.

  PloS one 20120101

• Using self-assembled monolayers to understand α8β1-mediated cell adhesion to RGD and FEI motifs in nephronectin.

  ACS chemical biology 20111021

• Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves.

  Amino acids 20111001

• Characterization of spontaneously generated prion-like conformers in cultured cells.

  Aging 20111001

• The effect of purity upon the triple-helical stability of collagenous peptides.

  Biomaterials 20110901

• Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

  PLoS pathogens 20110901

• Immobilization of aptamer-based molecular beacons onto optically-encoded micro-sized beads.

  Journal of nanoscience and nanotechnology 20110701

• The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways.

  PloS one 20110101

• In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.

  PloS one 20110101

• Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells.

  BMC cancer 20110101

• A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach.

  PloS one 20110101

• Enhancement of the click chemistry for the inverse Diels Alder technology by functionalization of amide-based monomers.

  International journal of medical sciences 20110101

• Development of a method for environmentally friendly chemical peptide synthesis in water using water-dispersible amino acid nanoparticles.

  Chemistry Central journal 20110101

• Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide.

  International journal of molecular sciences 20110101

• A Mycobacterium leprae Hsp65 mutant as a candidate for mitigating lupus aggravation in mice.

  PloS one 20110101

• Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.

  BMC biotechnology 20110101

• Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation.

  PloS one 20110101

• NNAlign: a web-based prediction method allowing non-expert end-user discovery of sequence motifs in quantitative peptide data.

  PloS one 20110101

• A new era of cancer treatment: carbon nanotubes as drug delivery tools.

  International journal of nanomedicine 20110101

• Adsorption of urinary proteins on the conventionally used urine collection tubes: possible effects on urinary proteome analysis and prevention of the adsorption by polymer coating.

  International journal of proteomics 20110101

• Activity of Antimicrobial Peptides and Conventional Antibiotics against Superantigen Positive Staphylococcus aureus Isolated from the Patients with Neoplastic and Inflammatory Erythrodermia.

  Chemotherapy research and practice 20110101

• Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

  Angewandte Chemie (International ed. in English) 20101227

• Characterization of Nα-Fmoc-protected ureidopeptides by electrospray ionization tandem mass spectrometry (ESI-MS/MS): differentiation of positional isomers.

  Journal of mass spectrometry : JMS 20101201

• Human OGA binds substrates in a conserved peptide recognition groove.

  The Biochemical journal 20101115

• Synthesis and splice-redirecting activity of branched, arginine-rich peptide dendrimer conjugates of peptide nucleic acid oligonucleotides.

  Bioconjugate chemistry 20101020

• Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation.

  Carbohydrate research 20101013

• Hydrogelation through self-assembly of fmoc-peptide functionalized cationic amphiphiles: potent antibacterial agent.

  The journal of physical chemistry. B 20100408

• Click chemistry aided synthesis of 1,4-substituted 1,2,3-triazole based N-Fmoc protected epsilon-amino acids: isolation, characterization and synthesis of novel triazole based unnatural amino acids.

  Protein and peptide letters 20100401

• Structural basis of cell wall cleavage by a staphylococcal autolysin.

  PLoS pathogens 20100301

• Semi-automated microwave-assisted SPPS: Optimization of protocols and synthesis of difficult sequences.

  Biopolymers 20100101

• Anti-infective activity of apolipoprotein domain derived peptides in vitro: identification of novel antimicrobial peptides related to apolipoprotein B with anti-HIV activity.

  BMC immunology 20100101

• Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids.

  PloS one 20100101

• Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry.

  International journal of medical sciences 20100101

• Synthesis and Biological Evaluation of New CRH Analogues.

  Bioinorganic chemistry and applications 20100101

• Identification of myotropic neuropeptides from the brain and corpus cardiacum-corpus allatum complex of the beetle, Zophobas atratus.

  Journal of insect science (Online) 20100101

• Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.

  PloS one 20100101

• Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin.

  PloS one 20100101

• Synthesis of Peptides from α- and β-Tubulin Containing Glutamic Acid Side-Chain Linked Oligo-Glu with Defined Length.

  International journal of peptides 20100101

• Crystallographic insight into collagen recognition by discoidin domain receptor 2.

  Structure (London, England : 1993) 20091209

• A study of the dynamic interaction of surfactants with graphite and carbon nanotubes using Fmoc-amino acids as a model system.

  Langmuir : the ACS journal of surfaces and colloids 20091006

• Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins.

  Journal of peptide science : an official publication of the European Peptide Society 20091001

• Surface aggregation of urinary proteins and aspartic Acid-rich peptides on the faces of calcium oxalate monohydrate investigated by in situ force microscopy.

  Calcified tissue international 20090601

• An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function.

  PLoS pathogens 20090301

• Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics.

  PloS one 20090101

• Synthesis of 4-amino-thiazole analogs of Fmoc-amino acids and thiazole linked N-orthogonally protected dipeptidomimetics.

  Protein and peptide letters 20090101

• The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells.

  BMC cancer 20090101

• Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice.

  PloS one 20090101

• Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation.

  Organic & biomolecular chemistry 20081107

• Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.

  Biochemistry 20080729

• RNA interference in mammalia cells by RNA-3'-PNA chimeras.

  International journal of molecular sciences 20080301

• Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels.

  PloS one 20080101

• Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients.

  PloS one 20080101

• A simple and economical method for the production of 13C,18O-labeled Fmoc-amino acids with high levels of enrichment: applications to isotope-edited IR studies of proteins.

  Organic letters 20071122

• Solid-phase peptide synthesis using nanoparticulate amino acids in water.

  Journal of peptide science : an official publication of the European Peptide Society 20070701

• Enantioseparation by CE with vancomycin as chiral selector: Improving the separation performance by dynamic coating of the capillary with poly(dimethylacrylamide).

  Electrophoresis 20070301

• Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding.

  BMC neuroscience 20070101

• Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.

  BMC structural biology 20070101

• Self-assembling Fmoc dipeptide hydrogel for in situ 3D cell culturing.

  BMC biotechnology 20070101

• Synthesis of libraries of 16beta-aminopropyl estradiol derivatives for targeting two key steroidogenic enzymes.

  ChemMedChem 20061101

• [Separation of enantiomers of amino acid derivatives by high performance liquid chromatography on teicoplanin chiral stationary phase].

  Se pu = Chinese journal of chromatography 20060301

• Chemical synthesis of analogs of the glycopeptide contulakin-G, an analgetically active conopeptide from Conus geographus.

  Carbohydrate research 20060116

• Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: synthesis, characterization and cellular uptake.

  Biomacromolecules 20060101

• Synthesis of spirohydantoins and spiro-2,5-diketopiperazines via resin-bound cyclic alpha,alpha-disubstituted alpha-amino esters.

  Journal of combinatorial chemistry 20060101

• Facile solid-phase synthesis of C-terminal peptide aldehydes and hydroxamates from a common Backbone Amide-Linked (BAL) intermediate.

  The journal of peptide research : official journal of the American Peptide Society 20051201

• Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.

  Organic letters 20050217

• Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization.

  BMC immunology 20050101

• Identification of Fmoc-beta-Ala-OH and Fmoc-beta-Ala-amino acid-OH as new impurities in Fmoc-protected amino acid derivatives.

  The journal of peptide research : official journal of the American Peptide Society 20050101

• Functional and structural characteristics of anticancer peptide Pep27 analogues.

  Cancer cell international 20050101

• Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides.

  The Journal of pharmacology and experimental therapeutics 20041001

• Geometrical and conformational preferences of the 9-fluorenylmethoxycarbonyl-amino moiety.

  Journal of peptide science : an official publication of the European Peptide Society 20040701

• Small molecule hydrogels based on a class of antiinflammatory agents.

  Chemical communications (Cambridge, England) 20040121

• Combinatorial library of peptidotriazoles: identification of [1,2,3]-triazole inhibitors against a recombinant Leishmania mexicana cysteine protease.

  Journal of combinatorial chemistry 20040101

• Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein.

  BMC structural biology 20040101

• Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral beta 3- and alpha-amino acids from Fmoc-protected aspartic acid.

  The Journal of organic chemistry 20030919

• The fluorenylmethoxycarbonyl group in solid phase synthesis.

  Journal of peptide science : an official publication of the European Peptide Society 20030901

• Antimicrobial peptides containing arginine.

  Biochemistry. Biokhimiia 20030801

• Understanding protease catalysed solid phase peptide synthesis.

  Organic & biomolecular chemistry 20030421

• Extensively stereodiversified scaffolds for use in diversity-oriented library synthesis.

  Organic letters 20030306

• Traceless liquid phase synthesis of piperazinediones.

  Combinatorial chemistry & high throughput screening 20030301

• Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides.

  Journal of medicinal chemistry 20030213

• Liquid-phase peptide synthesis on polyethylene glycol (PEG) supports using strategies based on the 9-fluorenylmethoxycarbonyl amino protecting group: application of PEGylated peptides in biochemical assays.

  Journal of peptide science : an official publication of the European Peptide Society 20020901

• Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.

  The Journal of organic chemistry 20020503

• Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa.

  Malaria journal 20020101

• The 2-chlorotrityl resin: a worthy addition to the medicinal chemist's toolbox.

  Current medicinal chemistry 20010501