84680-54-6 | Enalaprilat dihydrate

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%	in stock	$57.00	$40.00
10mg	98%	in stock	$101.00	$71.00
50mg	98%	in stock	$118.00	$83.00

Description

• Catalog Number: AB73368
• Chemical Name: Enalaprilat dihydrate
• CAS Number: 84680-54-6
• Molecular Formula: C18H28N2O7
• Molecular Weight: 384.4241
• MDL Number: MFCD00941393
• SMILES: OC(=O)[C@@H](N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C)CCc1ccccc1.O.O

Computed Properties

• Complexity: 490
• Covalently-Bonded Unit Count: 3
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 8

Literature

• Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.

  Toxicology and applied pharmacology 20140201

• Enalaprilat increases PPARβ/δ expression, without influence on PPARα and PPARγ, and modulate cardiac function in sub-acute model of daunorubicin-induced cardiomyopathy.

  European journal of pharmacology 20130815

• An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B₁ receptor in response to angiotensin converting enzyme inhibition.

  Vascular pharmacology 20120819

• Quantitative determination of lisinopril in human plasma by high performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.

  Biomedical chromatography : BMC 20120601

• Determination of enalapril and enalaprilat in small human serum quantities for pediatric trials by HPLC-tandem mass spectrometry.

  Biomedical chromatography : BMC 20120601

• Inhibition of ACE activity contributes to the intestinal structural compensation in a massive intestinal resection rat model.

  Pediatric surgery international 20120501

• The pharmacological mechanism of angiotensin-converting enzyme inhibition by green tea, Rooibos and enalaprilat - a study on enzyme kinetics.

  Phytotherapy research : PTR 20120401

• Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway.

  Molecules (Basel, Switzerland) 20120306

• Rapid and sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of enalapril and its major metabolite enalaprilat, in human plasma: application to a bioequivalence study.

  Drug testing and analysis 20120201

• Myocardial autophagy after severe burn in rats.

  PloS one 20120101

• Modulation of nitric oxide affects myocardial perfusion-contraction matching in anaesthetized dogs with recurrent no-flow ischaemia.

  Experimental physiology 20111201

• Insignificant response of the fetal placental circulation to arterial hypotension in sheep.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111001

• Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis.

  American journal of physiology. Renal physiology 20111001

• Acute effects of the ACE inhibitor enalaprilat on the pulmonary, cerebral and systemic blood flow and resistance after the bidirectional cavopulmonary connection.

  Heart (British Cardiac Society) 20110801

• Sublingual microcirculatory effects of enalaprilat in an ovine model of septic shock.

  Shock (Augusta, Ga.) 20110601

• What's new in Shock, June 2011?

  Shock (Augusta, Ga.) 20110601

• Gadolinium increases the vascular reactivity of rat aortic rings.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110501

• A novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase.

  Journal of cellular and molecular medicine 20110201

• Enalaprilat-mediated activation of kinin b(1) receptors and vasodilation in the rat isolated perfused kidney.

  Pharmacology 20110101

• A ligand-based approach to investigate the expression and function of angiotensin converting enzyme in intact human umbilical vein endothelial cells.

  Peptides 20100801

• Reduced systolic pressure load decreases cell-cycle activity in the fetal sheep heart.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100801

• Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbits.

  Acta ophthalmologica 20100501

• Attenuation of renal excretory responses to ANG II during inhibition of superoxide dismutase in anesthetized rats.

  American journal of physiology. Renal physiology 20100201

• Blood pressure, blood flow, and oxygenation in the clipped kidney of chronic 2-kidney, 1-clip rats: effects of tempol and Angiotensin blockade.

  Hypertension (Dallas, Tex. : 1979) 20100201

• A high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method using solid phase extraction for the simultaneous determination of plasma concentrations of enalapril and enalaprilate in hypertensive patients treated with different pharmaceutical formulations.

  Therapeutic drug monitoring 20091201

• Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme.

  The Journal of biological chemistry 20091113

• [Influence of the angiotensin converting enzyme inhibition on the functional proteinuria in rats].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20091001

• Early effects of high glucose in retinal tissue cultures Renin-Angiotensin system-dependent and -independent signaling.

  Neurobiology of disease 20090801

• [Effects of angiotensin (1-7) and enalaprilat on function of isolated rat heart perfused by burn serum].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20090601

• Nanocomposites coated with xyloglucan for drug delivery: In vitro studies.

  International journal of pharmaceutics 20090209

• Effect of hypotensive challenge on systemic hemodynamics and cerebral blood flow in persons with tetraplegia.

  Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20090201

• Simultaneous quantification of enalapril and enalaprilat in human plasma by high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.

  Journal of pharmaceutical and biomedical analysis 20090115

• [The use of parenteral enalaprilat for the treatment of patients with hypertensive crisis and incipient acute disturbance of cerebral circulation].

  Kardiologiia 20090101

• Myocardial protection with enalaprilat in patients unresponsive to ischemic preconditioning during percutaneous coronary intervention.

  Canadian journal of physiology and pharmacology 20081201

• [Effects of single or combined administration of cedilanid and enalaprilat on visceral damages in early stage of severe scald in rats].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20081201

• Protective effect of captopril and enalaprilat, angiotensin-converting enzyme inhibitors, on para-nonylphenol-induced *OH generation and dopamine efflux in rat striatum.

  Toxicology 20080904

• Transanal delivery of angiotensin converting enzyme inhibitor prevents colonic fibrosis in a mouse colitis model: development of a unique mode of treatment.

  Surgery 20080801

• [Protective effect of enalaprilat injection against early postburn organ damage in rats].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20080701

• Perioperative hypertension management.

  Vascular health and risk management 20080601

• [Protective effects of enalaprilat on the myocardial kinetics in rats at early stage of severe scald].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20080601

• Lack of direct interaction between enalaprilat and the kinin B1 receptors.

  Peptides 20080401

• 17Beta-estradiol increases basal but not bradykinin-stimulated release of active t-PA in young postmenopausal women.

  Hypertension (Dallas, Tex. : 1979) 20080401

• Low nanomolar concentration of mercury chloride increases vascular reactivity to phenylephrine and local angiotensin production in rats.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080301

• Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Expression of angiotensin I-converting enzymes and bradykinin B2 receptors in mouse inner medullary-collecting duct cells.

  International immunopharmacology 20080201

• Enalaprilat induced acute parotitis.

  The Journal of the Association of Physicians of India 20080201

• Angiotensin blockade and matrix synthesis by glomerular epithelial cells in high glucose: a further experimental insight into the pathophysiology of diabetic nephropathy.

  La Clinica terapeutica 20080101

• [The in vitro cross-effects of inhibitors of renin-angiotensin and fibrinolytic systems on the key enzymes of these systems].

  Bioorganicheskaia khimiia 20080101

• Effects of enalaprilat on acute necrotizing pancreatitis in rats.

  Inflammation 20071201

• Structural characterization of photodegradation products of enalapril and its metabolite enalaprilat obtained under simulated environmental conditions by hybrid quadrupole-linear ion trap-MS and quadrupole-time-of-flight-MS.

  Analytical chemistry 20071101

• Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril.

  Journal of cardiovascular pharmacology 20070801

• Effects of intracoronary low-dose enalaprilat on ventricular repolarization dynamics after direct percutaneous intervention for acute myocardial infarction.

  Pacing and clinical electrophysiology : PACE 20070501

• Effect of enalapril on the in vitro and in vivo peptidyl cleavage of a potent VLA-4 antagonist.

  Xenobiotica; the fate of foreign compounds in biological systems 20070501

• Pretreatment with intracoronary enalaprilat protects human myocardium during percutaneous coronary angioplasty.

  Journal of the American College of Cardiology 20070417

• Pharmacokinetics and pharmacodynamics of a nitric oxide-releasing derivative of enalapril in male beagles.

  Clinical and experimental pharmacology & physiology 20070401

• Reduced severity of a mouse colitis model with angiotensin converting enzyme inhibition.

  Digestive diseases and sciences 20070401

• Intracoronary enalaprilat during angioplasty for acute myocardial infarction: alleviation of postischaemic neurohumoral and inflammatory stress?

  Journal of internal medicine 20070201

• Effects of 4 classes of cardiovascular drugs on ventricular function in dogs with mitral regurgitation.

  Journal of veterinary internal medicine 20070101

• Angiotensin-(1-7) potentiates responses to bradykinin but does not change responses to angiotensin I.

  Canadian journal of physiology and pharmacology 20061101

• Systemic effects of angiotensin III in conscious dogs during acute double blockade of the renin-angiotensin-aldosterone-system.

  Acta physiologica (Oxford, England) 20061001

• Systemic and regional hemodynamic effects of enalaprilat infusion in experimental normotensive sepsis.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060901

• The effect of sublingual captopril versus intravenous enalaprilat on angiotensin II plasma levels.

  Pharmacy world & science : PWS 20060601

• Effects of candesartan and enalaprilat on the organ-specific microvascular permeability during haemorrhagic shock in rats.

  British journal of anaesthesia 20060401

• The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.

  European journal of endocrinology 20060201

• On call. I reread your articles on congestive heart failure when I was diagnosed with the condition last month. My breathing is back to normal, and I feel well. My doctor has prescribed all the medications you recommended, but he disagreed with one. He said that since I'm taking Vasotec, I should stop my aspirin. Do you agree?

  Harvard men's health watch 20060201

• Assessment of drug-induced QT interval prolongation in conscious rabbits.

  Journal of pharmacological and toxicological methods 20060101

• Interference of enalaprilat on glomerular permeability to macromolecules (IgG) in acute unilateral ureteral obstruction in rats.

  International braz j urol : official journal of the Brazilian Society of Urology 20060101

• Angiotensin-converting enzyme inhibition increases basal vascular tissue plasminogen activator release in women but not in men.

  Arteriosclerosis, thrombosis, and vascular biology 20051101

• Glomerular abundance of nephrin and podocin in experimental nephrotic syndrome: different effects of antiproteinuric therapies.

  American journal of physiology. Renal physiology 20051001

• Effects of enalaprilat on the renin-angiotensin-aldosterone system and on renal function during CO2 pneumoperitoneum.

  Journal of endourology 20051001

• Human vagal baroreflex sensitivity fluctuates widely and rhythmically at very low frequencies.

  The Journal of physiology 20050915

• Pharmacokinetics and pharmacodynamics profiles of enalapril maleate in healthy volunteers following determination of enalapril and enalaprilat by two specific enzyme immunoassays.

  Journal of clinical pharmacy and therapeutics 20050801

• The sensitivity of the cis/trans-isomerization of enalapril and enalaprilat to solvent conditions.

  The Journal of pharmacy and pharmacology 20050701

• Role of PGI2 and effects of ACE inhibition on the bradykinin potentiation by angiotensin-(1-7) in resistance vessels of SHR.

  Regulatory peptides 20050415

• Enalapril dosage in progressive chronic nephropathy: a randomised, controlled trial.

  European journal of clinical pharmacology 20050401

• High-performance liquid chromatographic determination of enalapril in human plasma by enzyme kinetic analytical method.

  Journal of pharmaceutical and biomedical analysis 20050401

• Partial angiotensin-converting enzyme inhibition during acute orthostatic stress in persons with tetraplegia.

  The journal of spinal cord medicine 20050101

• Simultaneous determination of enalapril and enalaprilat in human plasma by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Effects of enalaprilat infusion on hemodynamics and renal function in patients undergoing cardiac surgery.

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20041201

• Brain angiotensin-converting enzyme activity and autonomic regulation in heart failure.

  American journal of physiology. Heart and circulatory physiology 20041101

• Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase.

  American journal of physiology. Renal physiology 20041101

• Predominant postglomerular vascular resistance response to reflex renal sympathetic nerve activation during ANG II clamp in rabbits.

  American journal of physiology. Regulatory, integrative and comparative physiology 20041001

• A calorimetric study of the binding of lisinopril, enalaprilat and captopril to angiotensin-converting enzyme.

  Biophysical chemistry 20041001

• Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart.

  Hypertension (Dallas, Tex. : 1979) 20040901

• Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats.

  Journal of cardiovascular pharmacology 20040901

• Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme.

  Biochemistry 20040713

• Role of brain and peripheral angiotensin II in hypertension and altered arterial baroreflex programmed during fetal life in rat.

  Pediatric research 20040601

• Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers.

  Journal of cardiovascular pharmacology 20040501

• Losartan but not enalaprilat acutely reduces reperfusion ventricular tachyarrhythmias in hypertrophied rat hearts after low-flow ischaemia.

  The Journal of pharmacy and pharmacology 20040401

• Experimental design optimization of a capillary zone electrophoresis method for the screening of several diuretics and ACE inhibitors.

  Journal of chromatographic science 20040201

• Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.

  Journal of the American Society of Nephrology : JASN 20040101

• Determination of the cis-trans isomerization barrier of enalaprilat by dynamic capillary electrophoresis and computer simulation.

  Electrophoresis 20040101

• Characterization of the pharmacokinetic and pharmacodynamic properties of the angiotensin-converting enzyme inhibitor, enalapril, in horses.

  Journal of veterinary internal medicine 20040101

• Evaluation of the efficacy, safety and tolerability of intravenous enalaprilat in the treatment of grade III essential hypertension in Indian patients.

  Indian heart journal 20040101

• Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs.

  Critical care (London, England) 20040101

• Effect of angiotensin II type 2 receptor blockade on activation of mitogen-activated protein kinases after ischemia-reperfusion in isolated working rat hearts.

  Journal of cardiovascular pharmacology and therapeutics 20031201

• Omapatrilat increases renal endothelin in deoxycorticosterone acetate-salt hypertensive rats.

  Vascular pharmacology 20031201

• A novel activation process of protein kinase C in the remote, non-ischemic area of an infarcted heart is mediated by angiotensin-AT1 receptors.

  Journal of molecular and cellular cardiology 20031101

• Relative bioavailability study of 20-mg enalapril tablets in healthy male volunteers.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20031001

• NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.

  American journal of physiology. Heart and circulatory physiology 20030901

• Further studies on the effect of intracellular angiotensins on heart cell communication: on the role of endogenous angiotensin II.

  Regulatory peptides 20030815

• Differentiation between acute cyclosporine nephrotoxicity and acute tubular necrosis using enalaprilat renal scintigraphy in rats.

  Investigative radiology 20030801

• Do angiotensin-converting enzyme inhibitors directly stimulate the kinin B1 receptor?

  American journal of physiology. Heart and circulatory physiology 20030701

• Regional norepinephrine spillover in response to angiotensin-converting enzyme inhibition in healthy subjects.

  Journal of hypertension 20030701

• Effects of enalaprilat on venoconstriction to norepinephrine: role of prostaglandins.

  Cardiovascular research 20030701

• Effect of enalaprilat on postoperative hypertension after surgical repair of coarctation of the aorta.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20030701

• Angiotensin II-induced modulation of endothelium-dependent relaxation in rabbit mesenteric resistance arteries.

  The Journal of physiology 20030501

• Enalaprilat, losartan and LU 135252 in coronary blood flow regulation.

  European journal of clinical investigation 20030501

• Beneficial hemodynamic and renal effects of intravenous enalaprilat following coronary artery bypass surgery complicated by left ventricular dysfunction.

  Critical care medicine 20030501

• Is there an 'ACE' in the hole for postcoronary artery bypass graft myocardial dysfunction?

  Critical care medicine 20030501

• Bioequivalence study of two brands of enalapril tablets after single oral administration to healthy volunteers.

  International journal of clinical pharmacology and therapeutics 20030501

• RP-HPLC and NMR study of cis-trans isomerization of enalaprilat.

  Journal of pharmaceutical and biomedical analysis 20030326

• Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Role of angiotensin II in the neural control of renal function.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Angiotensin-converting enzyme inhibition increases human vascular tissue-type plasminogen activator release through endogenous bradykinin.

  Circulation 20030204

• Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization.

  American heart journal 20030201

• Simultaneous quantitation of enalapril and enalaprilat in human plasma by 96-well solid-phase extraction and liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20030101

• Angiotensin II blockade augments renal cortical microvascular pO2 indicating a novel, potentially renoprotective action.

  Nephron. Physiology 20030101

• Effects of an angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitors on burst forming units-erythroid in chronic hemodialysis patients.

  American journal of nephrology 20030101

• Captopril and enalaprilat decrease antioxidant defences in human endothelial cells and are unable to protect against apoptosis.

  Cell biology international 20030101

• Angiotensin-converting enzyme inhibition modulates high-glucose-induced extracellular matrix changes in mouse glomerular epithelial cells.

  Nephron. Experimental nephrology 20030101

• Prejunctional AT(1) receptor subtype-dependent modification of neurotransmitter releases in canine isolated splenic arteries.

  Autonomic & autacoid pharmacology 20030101

• Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A(2A)-receptor-mediated coronary vasodilation.

  Journal of the American College of Cardiology 20021106

• Angiotensin II contributes to arterial compliance in congestive heart failure.

  American journal of physiology. Heart and circulatory physiology 20021001

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  British journal of anaesthesia 20021001

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  European journal of clinical investigation 20021001

• Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition.

  Journal of the American Society of Nephrology : JASN 20020901

• Angiotensin inhibition and coronary autoregulation in a canine model of LV hypertrophy.

  Basic research in cardiology 20020901

• Impaired regulation of renal oxygen consumption in spontaneously hypertensive rats.

  Journal of the American Society of Nephrology : JASN 20020701

• Icatibant blocks but does not reverse ACE inhibitor renal effect in Goldblatt rabbit.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20020701

• Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism.

  Circulation 20020611

• Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration.

  International journal of pharmaceutics 20020604

• Renal nerve stimulation augments effect of intraluminal angiotensin II on proximal tubule transport.

  American journal of physiology. Renal physiology 20020601

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  Stroke 20020601

• Determination of enalapril and enalaprilat by enzyme linked immunosorbent assays: application to pharmacokinetic and pharmacodynamic analysis.

  Fundamental & clinical pharmacology 20020601

• Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor.

  The Journal of biological chemistry 20020510

• AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts.

  American journal of physiology. Heart and circulatory physiology 20020401

• Enalaprilat improves systemic cardiovascular parameters and mesenteric blood flow during hypotensive resuscitation from hemorrhagic shock in dogs.

  Shock (Augusta, Ga.) 20020301

• Studies on the angiotensin-converting enzyme and the kinin B2 receptor in the rabbit jugular vein: modulation of contractile response to bradykinin.

  Canadian journal of physiology and pharmacology 20020201

• Effect of angiotensin-converting enzyme inhibitors on liver regeneration in rats.

  Hepato-gastroenterology 20020101

• Effects of intracoronary low-dose enalaprilat as an adjunct to primary percutaneous transluminal coronary angiography in acute myocardial infarction.

  The American journal of cardiology 20011215

• High serum enalaprilat in chronic renal failure.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20011201

• Enalaprilat blunts reflexive increases in cardiac interstitial norepinephrine in conscious rats.

  Journal of hypertension 20011101

• The pharmacokinetics of enalapril in children and infants with hypertension.

  Journal of clinical pharmacology 20011001

• Inhibition of serum angiotensin-converting enzyme in rabbits after intravenous administration of enalaprilat-loaded intact erythrocytes.

  The Journal of pharmacy and pharmacology 20010901

• Pathophysiological roles of endogenous endothelin-1 in dogs with chronic heart failure produced by rapid right ventricular pacing.

  The Journal of pharmacology and experimental therapeutics 20010801

• Cardiac nitric oxide production due to angiotensin-converting enzyme inhibition decreases beta-adrenergic myocardial contractility in patients with dilated cardiomyopathy.

  Journal of the American College of Cardiology 20010801

• High tissue affinity angiotensin-converting enzyme inhibitors improve endothelial function and reduce infarct size.

  The Annals of thoracic surgery 20010801

• Effects of enalaprilat on cardiorespiratory, hemodynamic, and hematologic variables in exercising horses.

  American journal of veterinary research 20010701

• Effect of column temperature on the behaviour of some angiotensin converting enzyme inhibitors during high-performance liquid chromatographic analysis.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• The bladder angiotensin system in female rats: response to infusions of angiotensin I and the angiotensin converting enzyme inhibitor enalaprilat.

  The Journal of urology 20010501

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  American journal of physiology. Renal physiology 20010401

• Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease.

  Journal of the American College of Cardiology 20010315

• The renal nerve is required for regulation of proximal tubule transport by intraluminally produced ANG II.

  American journal of physiology. Renal physiology 20010301

• The pancreatic islets in spontaneously hypertensive rats: islet blood flow and insulin production.

  European journal of endocrinology 20010201

• Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20010201

• A simple HPLC method for quantitation of enalaprilat.

  Journal of pharmaceutical and biomedical analysis 20010201

• Haemodynamic and renal effects of intravenous enalaprilat during coronary artery bypass graft surgery in patients with ischaemic heart dysfunction.

  British journal of anaesthesia 20010201

• Treatment of chronic hypertension with intravenous enalaprilat and transdermal clonidine.

  Pediatric nephrology (Berlin, Germany) 20010101

• Effects of digoxin, furosemide, enalaprilat and metoprolol on endothelial function in young normotensive subjects.

  Clinical and experimental pharmacology & physiology 20010101

• Enalaprilat attenuates ischemic rises in intracellular sodium in the isolated rat heart via the bradykinin receptor.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20010101

• Comparative study of effects of angiotensin II receptor antagonist, KD3-671, and angiotensin converting enzyme inhibitor, enalaprilat, on cough reflex in guinea pig.

  European journal of drug metabolism and pharmacokinetics 20010101

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  Drug delivery 20010101

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  Polish journal of pharmacology 20010101

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  Japanese journal of pharmacology 19931101

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