86318-61-8 | (tert-Butyldimethylsilyl)acetylene

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$19.00	$13.00
5g	98%	in stock	$42.00	$29.00
10g	98%	in stock	$73.00	$51.00
25g	98%	in stock	$76.00	$53.00
100g	98%	in stock	$233.00	$163.00

Description

• Catalog Number: AC15351
• Chemical Name: (tert-Butyldimethylsilyl)acetylene
• CAS Number: 86318-61-8
• Molecular Formula: C8H16Si
• Molecular Weight: 140.2981
• MDL Number: MFCD00191877
• SMILES: C#C[Si](C(C)(C)C)(C)C

Upstream Synthesis Route

(t-Butyldimethylsilyl)acetylene is commonly used in chemical synthesis as a versatile building block. Its unique structure, with a terminal alkyne group and a bulky t-butyl group, provides a range of opportunities for functionalization and manipulation in organic reactions.One of the main applications of (t-Butyldimethylsilyl)acetylene is in the synthesis of alkynes through Sonogashira cross-coupling reactions. By reacting with aryl or vinyl halides, this compound can be used to form new carbon-carbon bonds, allowing for the creation of complex organic molecules. The presence of the silyl group also facilitates protection of the alkyne functionality in multi-step syntheses, providing stability during various transformations.Furthermore, (t-Butyldimethylsilyl)acetylene can serve as a precursor for the introduction of alkynyl groups in organic molecules. Its ability to undergo selective deprotection reactions enables the controlled release of the alkyne functionality under specific conditions, contributing to the efficient synthesis of target compounds.Overall, the use of (t-Butyldimethylsilyl)acetylene in chemical synthesis offers chemists a valuable tool for the construction of diverse organic structures and the exploration of new reaction pathways.