87-48-9 | 5-Bromoisatin

Packsize	Purity	Availability	Price	Discounted Price
1g	90%	in stock	$15.00	$10.00
5g	90%	in stock	$16.00	$11.00
25g	90%	in stock	$31.00	$22.00
100g	90%	in stock	$94.00	$66.00
500g	90%	in stock	$446.00	$312.00

Description

• Catalog Number: AB69007
• Chemical Name: 5-Bromoisatin
• CAS Number: 87-48-9
• Molecular Formula: C8H4BrNO2
• Molecular Weight: 226.0269
• MDL Number: MFCD00005719
• SMILES: Brc1ccc2c(c1)C(=O)C(=O)N2
• NSC Number: 4980

Computed Properties

• Complexity: 241
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

5-Bromoindoline-2,3-dione, also known as $name$, is a versatile building block in chemical synthesis, commonly used for the formation of various heterocyclic compounds. In organic chemistry, this compound serves as a key intermediate in the construction of diverse molecular structures due to its unique reactivity and functional groups. Its application extends to the synthesis of pharmaceuticals, agrochemicals, and materials science. By incorporating $name$ into chemical reactions, chemists can efficiently access novel compounds with potential biological or industrial significance. The reactivity of 5-Bromoindoline-2,3-dione allows for the introduction of specific functional groups and substitution patterns, making it a valuable tool for designing complex molecules in synthetic chemistry.

Literature

• 5-Bromo-1-(prop-2-en-1-yl)-2,3-dihydro-1H-indole-2,3-dione.

  Acta crystallographica. Section E, Structure reports online 20120101

• Synthesis and anticancer activity of isatin-based pyrazolines and thiazolidines conjugates.

  Archiv der Pharmazie 20110801

• 1-(5-Bromo-2-oxoindolin-3-yl-idene)thio-semicarbazide acetonitrile monosolvate.

  Acta crystallographica. Section E, Structure reports online 20110701

• Synthesis characterization and biological activity study of new schiff and mannich bases and some metal complexes derived from isatin and dithiooxamide.

  Bioinorganic chemistry and applications 20110101

• QSAR study of isatin analogues as in vitro anti-cancer agents.

  European journal of medicinal chemistry 20100301

• Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.

  ChemMedChem 20091207

• Design, Synthesis and antiHIV activity of Novel Isatine-Sulphonamides.

  Indian journal of pharmaceutical sciences 20080101

• Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.

  Journal of medicinal chemistry 20070419

• In vitro cytotoxicity evaluation of some substituted isatin derivatives.

  Bioorganic & medicinal chemistry 20070115

• Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.

  Bioorganic & medicinal chemistry letters 20031020