870-93-9 | Dl-homocystine

Packsize	Purity	Availability	Price	Discounted Price
10g	95%	in stock	$15.00	$11.00
100g	97%	in stock	$139.00	$97.00
500g	95%	in stock	$276.00	$193.00

Description

• Catalog Number: AB45989
• Chemical Name: Dl-homocystine
• CAS Number: 870-93-9
• Molecular Formula: C8H16N2O4S2
• Molecular Weight: 268.3536
• MDL Number: MFCD00069587
• SMILES: NC(C(=O)O)CCSSCCC(C(=O)O)N

Computed Properties

• Complexity: 216
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 9
• Undefined Atom Stereocenter Count: 2
• XLogP3: -5.6

Literature

• Chemiluminescence detection of amino acids and related compounds using acidic potassium permanganate, manganese(IV) or tris(2,2'-bipyridine)ruthenium(III).

  Talanta 20120915

• Diffuse reflectance spectroscopy of fibrous proteins.

  Amino acids 20120901

• LDL S-homocysteinylation decrease in chronic kidney disease patients undergone lipid lowering therapy.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

• DNA/nickel oxide nanoparticles/osmium(III)-complex modified electrode toward selective oxidation of l-cysteine and simultaneous detection of l-cysteine and homocysteine.

  Bioelectrochemistry (Amsterdam, Netherlands) 20120801

• Neonatal atypical hemolytic uremic syndrome due to methylmalonic aciduria and homocystinuria.

  Pediatric nephrology (Berlin, Germany) 20120801

• Does maternal Helicobacter pylori infection increase the risk of occurrence of neural tube defects in newborns in Northern Iran?

  Neurosciences (Riyadh, Saudi Arabia) 20120701

• The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients.

  Neurochemical research 20120501

• Fetal variant of circle of the Willis and bilateral symmetrical parietal stroke.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120401

• The effect of methionine supplementation of the AIN-93G semi-synthetic diet on the levels of homocysteine and lipids in experimental rats.

  The journal of nutrition, health & aging 20120401

• Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases.

  Archives of medical science : AMS 20120227

• Complementary effects of multivitamin and omega-3 fatty acid supplementation on indices of cardiovascular health in individuals with elevated homocysteine.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20120201

• Fast analysis of wine for total homocysteine content by high-performance liquid chromatography.

  Amino acids 20120101

• Homocysteinylated albumin promotes increased monocyte-endothelial cell adhesion and up-regulation of MCP1, Hsp60 and ADAM17.

  PloS one 20120101

• Elevated plasma homocysteine in association with decreased vitamin B(12), folate, serotonin, lipids and lipoproteins in depressed patients.

  African journal of psychiatry 20120101

• Activated human CD4+ T cells express transporters for both cysteine and cystine.

  Scientific reports 20120101

• Pupil-sparing complete third nerve palsy from cryptogenic midbrain stroke in an otherwise-healthy young adult with patent foramen ovale.

  Middle East African journal of ophthalmology 20120101

• Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities.

  Rejuvenation research 20111201

• Biomarkers in the early period of acute myocardial infarction in rat serum and protective effects of Shexiang Baoxin Pill using a metabolomic method.

  Journal of ethnopharmacology 20111118

• Methylenetetrahydrofolate reductase (MTHFR) deficiency and infantile epilepsy.

  Brain & development 20111001

• High consumption of Ω-3 polyunsaturated fatty acids decrease plasma homocysteine: a meta-analysis of randomized, placebo-controlled trials.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110901

• Metabolic syndrome and serum homocysteine in patients with bipolar disorder and schizophrenia treated with second generation antipsychotics.

  Psychiatry research 20110830

• Direct detection of biologically significant thiols and disulfides with manganese(IV) chemiluminescence.

  Analytical chemistry 20110801

• The organotelluride catalyst LAB027 prevents colon cancer growth in the mice.

  Cell death & disease 20110801

• The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells.

  Investigative ophthalmology & visual science 20110701

• Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.

  Journal of neurochemistry 20110601

• Sulfur- and seleno-containing amino acids.

  Amino acids 20110601

• Distinguishing the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) from other diamino acids.

  Toxicon : official journal of the International Society on Toxinology 20110401

• Vascular presentation of cystathionine beta-synthase deficiency in adulthood.

  Journal of inherited metabolic disease 20110201

• Oxidative stress in schizophrenia: an integrated approach.

  Neuroscience and biobehavioral reviews 20110101

• Bilateral central retinal arterial obstruction following head trauma: a very rare case report.

  Indian journal of ophthalmology 20110101

• Reconciling the evidence on serum homocysteine and ischaemic heart disease: a meta-analysis.

  PloS one 20110101

• Efficacy of a family practice-based lifestyle intervention program to increase physical activity and reduce clinical and physiological markers of vascular health in patients with high normal blood pressure and/or high normal blood glucose (SNAC): study protocol for a randomized controlled trial.

  Trials 20110101

• [The relationship between plasma homocysteine levels and diabetic peripheral neuropathy].

  Zhonghua nei ke za zhi 20110101

• Treatment of homocystinuria-related dystonia with deep brain stimulation: a case report.

  Stereotactic and functional neurosurgery 20110101

• Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.

  Nutrition & metabolism 20110101

• Experimental evidence of oxidative stress in plasma of homocystinuric patients: a possible role for homocysteine.

  Molecular genetics and metabolism 20110101

• Cation exchange HPLC analysis of desmosines in elastin hydrolysates.

  Analytical and bioanalytical chemistry 20110101

• Alteration of plasma glutamate and glutamine levels in children with high-functioning autism.

  PloS one 20110101

• Effect of a vitamin/mineral supplement on children and adults with autism.

  BMC pediatrics 20110101

• [Cardiovascular disease prevention: results from Programma FASEN - H San Raffaele].

  Giornale italiano di medicina del lavoro ed ergonomia 20110101

• Neural tube defects between folate metabolism and genetics.

  Indian journal of human genetics 20110101

• Mapping of selenium metabolic pathway in yeast by liquid chromatography-Orbitrap mass spectrometry.

  Analytical chemistry 20101001

• Determination of homocysteine thiolactone, reduced homocysteine, homocystine, homocysteine-cysteine mixed disulfide, cysteine and cystine in a reaction mixture by overimposed pressure/voltage capillary electrophoresis.

  Talanta 20100915

• Improved endothelial function and lipid profile compensate for impaired hemostatic and inflammatory status in iatrogenic chronic subclinical hyperthyroidism of thyroid cancer patients on L-t4 therapy.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20100601

• Comparison of selenohomolanthionine and selenomethionine in terms of selenium distribution and toxicity in rats by bolus administration.

  Metallomics : integrated biometal science 20100601

• Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium.

  American journal of respiratory and critical care medicine 20100501

• A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats.

  Journal of toxicologic pathology 20100301

• Determination of total homocysteine in plasma using liquid chromatography coupled to tandem mass spectrometry (LC/MS/MS).

  Methods in molecular biology (Clifton, N.J.) 20100101

• The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFkappaB signaling pathway and nitric oxide induction in macrophages.

  Journal of inflammation (London, England) 20100101

• Cobalamin deficiency, hyperhomocysteinemia, and dementia.

  Neuropsychiatric disease and treatment 20100101

• Assessment and management of nutrition in older people and its importance to health.

  Clinical interventions in aging 20100101

• Prevention and treatment of peripheral neuropathy after bariatric surgery.

  Current treatment options in neurology 20100101

• Researching Effective Strategies to Improve Insulin Sensitivity in Children and Teenagers - RESIST. A randomised control trial investigating the effects of two different diets on insulin sensitivity in young people with insulin resistance and/or pre-diabetes.

  BMC public health 20100101

• Can high-sensitivity C-reactive protein and plasma homocysteine levels independently predict the prognosis of patients with functional disability after first-ever ischemic stroke?

  European neurology 20100101

• Plasma oxidized LDL and thiol-containing molecules in patients with exudative age-related macular degeneration.

  Molecular vision 20100101

• Polymorphisms of methylenetetrahydrofolate reductase gene as the genetic predispositions of coronary artery diseases in eastern India.

  Journal of cardiovascular disease research 20100101

• Homocystinuria: A rare condition presenting as stroke and megaloblastic anemia.

  Journal of pediatric neurosciences 20100101

• Prevalence of modifiable cardiovascular risk factors in long-term renal transplant patients.

  International journal of nephrology and renovascular disease 20100101

• Moyamoya syndrome in a known case of pulmonary tuberculosis.

  Journal of neurosciences in rural practice 20100101

• Visual and colorimetric detection of Hg(2+) by cloud point extraction with functionalized gold nanoparticles as a probe.

  Chemical communications (Cambridge, England) 20091207

• Clinical assay of four thiol amino acid redox couples by LC-MS/MS: utility in thalassemia.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091015

• Cysteinylation and homocysteinylation of plasma protein thiols during ageing of healthy human beings.

  Journal of cellular and molecular medicine 20090901

• Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.

  Acta physiologica (Oxford, England) 20090901

• Inflammatory markers and intimal media thickness in diabetics with negative myocardial perfusion scan.

  Journal of clinical medicine research 20090601

• Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats.

  The Journal of nutritional biochemistry 20090301

• Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.

  Bone 20090301

• Hypoxia tolerance and retinal vein occlusion: a pilot evaluation.

  European journal of ophthalmology 20090101

• Therapeutic antioxidant medical gas.

  Journal of clinical biochemistry and nutrition 20090101

• Homocystine levels, polymorphisms and the risk of ischemic stroke in young Asian Indians.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20090101

• Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial.

  PloS one 20090101

• Differential expression of Gs in a murine model of homocysteinemic heart failure.

  Vascular health and risk management 20090101

• Anchoring secreted proteins in endoplasmic reticulum by plant oleosin: the example of vitamin B12 cellular sequestration by transcobalamin.

  PloS one 20090101

• Homocysteine disulphides and vascular disease.

  Disease markers 20090101

• Recurrent venous thromboses in HIV-2 patient.

  Indian journal of sexually transmitted diseases and AIDS 20090101

• Comparative studies on homocysteine and its metabolite-homocysteine thiolactone action in blood platelets in vitro.

  Platelets 20081101

• Serum vitamin B12 deficiency and hyperhomocystinemia: a reversible cause of acute chorea, cerebellar ataxia in an adult with cerebral ischemia.

  Journal of the neurological sciences 20081015

• Bipolar disorder, homocysteine and white matter hyperintensities.

  Bipolar disorders 20080901

• Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080801

• Effect of the methylenetetrahydrofolate reductase gene polymorphisms on homocysteine, folate and vitamin B12 in patients with bipolar disorder and relatives.

  Progress in neuro-psychopharmacology & biological psychiatry 20080701

• Thromboelastography in children with coagulation factor deficiencies.

  British journal of haematology 20080601

• Effect of dietary soybean protein level on the plasma homocysteine concentration in rats.

  Bioscience, biotechnology, and biochemistry 20080601

• A fast liquid chromatographic tandem mass spectrometric method for the simultaneous determination of total homocysteine and methylmalonic acid.

  Analytical and bioanalytical chemistry 20080501

• Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation.

  Circulation research 20080425

• Non-fasting plasma total homocysteine reference interval using the Vitros homocysteine assay standardized against NIST SRM 1955.

  Clinica chimica acta; international journal of clinical chemistry 20080201

• The role of thrombophilia and thyroid autoimmunity in unexplained infertility, implantation failure and recurrent spontaneous abortion.

  Human reproduction (Oxford, England) 20080201

• Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine.

  Neurobiology of aging 20080101

• Homocysteine activates platelets in vitro.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080101

• Rapid detection of S-adenosyl homocysteine using self-assembled optical diffraction gratings.

  Angewandte Chemie (International ed. in English) 20080101

• Hyperhomocysteinemia and recurrent carotid stenosis.

  BMC cardiovascular disorders 20080101

• Homocysteine measurement by Vitros Microtip homocysteine assay.

  Clinical chemistry and laboratory medicine 20080101

• Environmental influences on familial discordance of phenotype in people with homocystinuria: a case report.

  Journal of medical case reports 20080101

• Intravenous N-acetylcysteine with saline hydration improves renal function and ameliorates plasma total homocysteine in patients undergoing cardiac angiography.

  Renal failure 20080101

• Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer.

  PloS one 20080101

• The role of vitamins and minerals in psychiatry.

  Integrative medicine insights 20080101

• Selective phosphorescence chemosensor for homocysteine based on an iridium(III) complex.

  Inorganic chemistry 20071224

• Facile syntheses of [35S]homocysteine-thiolactone, [35S]homocystine, [35S]homocysteine, and [S-nitroso-35S]homocysteine.

  Analytical biochemistry 20071101

• Arterial ischemic stroke in childhood: risk factors and outcome in old versus new era.

  Journal of child neurology 20071001

• Hyperhomocysteinemia and elevated ox-LDL in Tunisian type 2 diabetic patients: role of genetic and dietary factors.

  Clinical biochemistry 20070901

• Elution behavior of diaminopimelic acid and related diamino acids using the advanced Marfey's method.

  Journal of chromatography. A 20070810

• Homocysteine induces cell death in H9C2 cardiomyocytes through the generation of peroxynitrite.

  Biochemical and biophysical research communications 20070803

• Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet.

  Neurobiology of aging 20070801

• Experimental hyperhomocysteinemia reduces bone quality in rats.

  Clinical chemistry 20070801

• Traditional and 'new' cardiovascular risk markers and factors in pediatric dialysis patients.

  Pediatric nephrology (Berlin, Germany) 20070701

• Interactive effects of homocysteine and copper on angiogenesis in porcine isolated saphenous vein.

  The Annals of thoracic surgery 20070701

• Invited commentary.

  The Annals of thoracic surgery 20070701

• The organotellurium compound ammonium trichloro(dioxoethylene-o,o')tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice.

  The FEBS journal 20070601

• Risk factors for cardiovascular disease in patients undergoing peritoneal dialysis.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20070601

• Hyperhomocysteinemia and myocardial expression of brain natriuretic peptide in rats.

  Clinical chemistry 20070401

• A rationale for cystine supplementation in severe homocystinuria.

  Journal of inherited metabolic disease 20070201

• Soy compared to casein meal replacement shakes with energy-restricted diets for obese women: randomized controlled trial.

  Metabolism: clinical and experimental 20070201

• Elevated homocysteine is associated with reduced regional left ventricular function: the Multi-Ethnic Study of Atherosclerosis.

  Circulation 20070116

• Specific postcolumn detection method for HPLC assay of homocysteine based on aggregation of fluorosurfactant-capped gold nanoparticles.

  Analytical chemistry 20070115

• Homocysteine-induced changes in vascular reactivity of guinea-pig pulmonary arteries: role of the oxidative stress and poly (ADP-ribose) polymerase activation.

  Pulmonary pharmacology & therapeutics 20070101

• Quantification of intracellular homocysteine by stable isotope dilution liquid chromatography/tandem mass spectrometry.

  Biomedical chromatography : BMC 20070101

• Mechanisms of homocysteine toxicity in humans.

  Amino acids 20070101

• Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.

  Thrombosis research 20070101

• Oxidative DNA damage and level of thiols as related to polymorphisms of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's diseases.

  Acta neurobiologiae experimentalis 20070101

• Folate augmentation of treatment - evaluation for depression (FolATED): protocol of a randomised controlled trial.

  BMC psychiatry 20070101

• Selective gold-nanoparticle-based 'turn-on' fluorescent sensors for detection of mercury(II) in aqueous solution.

  Analytical chemistry 20061215

• The relationship between micronuclei in human lymphocytes and selected micronutrients in vegetarians and non-vegetarians.

  Mutation research 20061210

• Re: 'confounding of the relation between homocysteine and peripheral arterial disease by lead, cadmium, and renal function'.

  American journal of epidemiology 20061201

• Coronary calcification, homocysteine, C-reactive protein and the metabolic syndrome in Type 2 diabetes: the Prospective Evaluation of Diabetic Ischaemic Heart Disease by Coronary Tomography (PREDICT) Study.

  Diabetic medicine : a journal of the British Diabetic Association 20061101

• Enantioselectivity of redox reaction of DOPA at the gold electrode modified with a self-assembled monolayer of homocysteine.

  Journal of the American Chemical Society 20061018

• Interaction of homocysteine and conventional predisposing factors on risk of ischaemic stroke in young people: consistency in phenotype-disease analysis and genotype-disease analysis.

  Journal of neurology, neurosurgery, and psychiatry 20061001

• Recurrent dystonia in homocystinuria: a metabolic pathogenesis.

  Movement disorders : official journal of the Movement Disorder Society 20061001

• [Serum level of homocysteine and the development of collateral circulation in patients with severe coronary artery stenosis].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001

• Biochemistry of homocysteine in health and diseases.

  Indian journal of biochemistry & biophysics 20061001

• A new method for determination of plasma homocystine by isotope dilution and electrospray tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914

• Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos.

  European journal of nutrition 20060901

• Increased plasma homocysteine and allantoin levels in coronary artery disease: possible link between homocysteine and uric acid oxidation.

  Acta cardiologica 20060801

• Homocysteine induced cardiovascular events: a consequence of long term anabolic-androgenic steroid (AAS) abuse.

  British journal of sports medicine 20060701

• Analysis of urine for cysteine, cysteinylglycine, and homocysteine by high-performance liquid chromatography.

  Analytical and bioanalytical chemistry 20060701

• S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.

  Journal of medicinal chemistry 20060629

• Effects of 1 year of treatment with pioglitazone or rosiglitazone added to glimepiride on lipoprotein (a) and homocysteine concentrations in patients with type 2 diabetes mellitus and metabolic syndrome: a multicenter, randomized, double-blind, controlled clinical trial.

  Clinical therapeutics 20060501

• Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study.

  AIDS (London, England) 20060424

• Confounding of the relation between homocysteine and peripheral arterial disease by lead, cadmium, and renal function.

  American journal of epidemiology 20060415

• Failure of homocysteine to induce neural tube defects in a mouse model.

  Birth defects research. Part B, Developmental and reproductive toxicology 20060401

• [Case of cerebral venous thrombosis due to graves' disease with increased factor VIII activity].

  Rinsho shinkeigaku = Clinical neurology 20060401

• Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease.

  Circulation research 20060303

• ApoA-I: a missing link between homocysteine and lipid metabolism?

  Circulation research 20060303

• Thyroid function during B-vitamin supplementation of patients on antiepileptic drugs.

  Clinical biochemistry 20060301

• The effect of in vitro homocystinuria on the suckling rat hippocampal acetylcholinesterase.

  Metabolic brain disease 20060301

• Liquid chromatography-tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217

• Homocysteine transport by human aortic endothelial cells: identification and properties of import systems.

  Archives of biochemistry and biophysics 20060215

• Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease.

  Neurobiology of aging 20060201

• Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs.

  Microbiology (Reading, England) 20060201

• Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.

  Lipids in health and disease 20060101

• Amino acids, arginase and nitric oxide in vascular health.

  Clinical and experimental pharmacology & physiology 20060101

• Cardiovascular effects of hyperhomocysteinemia in conscious unrestrained rats.

  American journal of hypertension 20060101

• Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study.

  International journal of biological sciences 20060101

• Suppression of thiol exchange reaction in the determination of reduced-form thiols by high-performance liquid chromatography with fluorescence detection after derivatization with fluorogenic benzofurazan reagent, 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate and 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole.

  Biomedical chromatography : BMC 20060101

• Homocysteine--should we screen and treat in preventive cardiology programs?

  Journal of cardiopulmonary rehabilitation 20060101

• Total plasma homocysteine in Bulgarian population measured by high-performance liquid chromatography with fluorescence detection--comparison with fluorescence polarization immunoassay.

  Clinical laboratory 20060101

• Hyperhomocysteinemia and mortality after coronary artery bypass grafting.

  PloS one 20060101

• Excitotoxic neuronal injury in chronic homocysteine neurotoxicity studied in vitro: the role of NMDA and group I metabotropic glutamate receptors.

  Acta neurobiologiae experimentalis 20060101

• [The influence of tobacco smoke on plasma atherogenic compounds levels in active smokers (preliminary report)].

  Przeglad lekarski 20060101

• Adaptation of a high-performance liquid chromatographic method for quantitative determination of homocysteine in urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215

• Vitamin B12 and homocysteine.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20051122

• Vitamin B12 and homocysteine.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20051122

• [Renal impairment in patients with methylmalonic aciduria: a review of five cases].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20051101

• [Untreated homocystinuria in adulthood].

  Deutsche medizinische Wochenschrift (1946) 20051028

• Obstructive sleep apnoea and plasma homocysteine.

  European heart journal 20051001

• Schizophrenia and single-carbon metabolism.

  Progress in neuro-psychopharmacology & biological psychiatry 20050901

• The central nervous system in animal models of hyperhomocysteinemia.

  Progress in neuro-psychopharmacology & biological psychiatry 20050901

• Homocysteine and schizophrenia: from prenatal to adult life.

  Progress in neuro-psychopharmacology & biological psychiatry 20050901

• Effect of caspase 9 related signaling molecules on the apoptosis of human vascular endothelial cell induced by homocysteine.

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20050801

• Homocysteinic acid causes oxidative stress in lymphocytes by potentiating toxic effect of NMDA.

  Bulletin of experimental biology and medicine 20050701

• Vitamin B12, homocysteine and carotid plaque in the era of folic acid fortification of enriched cereal grain products.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050607

• Analysis of plasma amino acids by HPLC with photodiode array and fluorescence detection.

  Clinica chimica acta; international journal of clinical chemistry 20050401

• Obstructive sleep apnoea and plasma homocysteine.

  European heart journal 20050301

• Plasma homocysteine is a risk factor for recurrent vascular events in young patients with an ischaemic stroke or TIA.

  Journal of neurology 20050301

• A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.

  Journal of chromatography. A 20050225

• Effect of clopidogrel on platelet aggregation and intimal hyperplasia following carotid endarterectomy in the rat.

  Vascular 20050101

• Altered thiol pattern in plasma of subjects affected by rheumatoid arthritis.

  Clinical and experimental rheumatology 20050101

• Primary prevention of Down's syndrome.

  International journal of medical sciences 20050101

• On the interaction of oxovanadium(IV) with homocysteine.

  Biological trace element research 20050101

• Postoperative secondary glaucoma and anterior staphyloma in a patient with homocystinuria.

  Journal of pediatric ophthalmology and strabismus 20050101

• Relation between homocysteine and biochemical bone turnover markers and bone mineral density in peri- and post-menopausal women.

  Clinical chemistry and laboratory medicine 20050101

• Atorvastatin suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells.

  Clinical chemistry and laboratory medicine 20050101

• The MTHFR C677T polymorphism is associated with depressive episodes in patients from Northern Ireland.

  Journal of psychopharmacology (Oxford, England) 20041201

• Saratin (an inhibitor of platelet-collagen interaction) decreases platelet aggregation and homocysteine-mediated postcarotid endarterectomy intimal hyperplasia in a dose-dependent manner.

  American journal of surgery 20041201

• Biochemical signs of impaired cobalamin status during and after radiotherapy for rectal cancer.

  International journal of radiation oncology, biology, physics 20041101

• Lack of association between baseline plasma homocysteine concentrations and restenosis rates after a first elective percutaneous coronary intervention without stenting.

  Heart (British Cardiac Society) 20041101

• Hyperhomocysteinemia measured by immunoassay: a valid measure of coronary artery atherosclerosis.

  Archives of pathology & laboratory medicine 20041101

• Can vitamin therapy prevent restenosis? Conflicting studies indicate the jury is still out on folate therapy after angioplasty.

  Health news (Waltham, Mass.) 20041101

• [Homocystine as a new factor of risk of atherosclerosis and thrombosis (lecture)].

  Klinicheskaia laboratornaia diagnostika 20041001

• HPLC simultaneous analysis of thiols and disulfides: on-line reduction and indirect fluorescence detection without derivatization.

  The Analyst 20040801

• Plasma homocysteine in obstructive sleep apnoea.

  European heart journal 20040801

• [The mechanism of homocysteine in Kkay mice diabetic nephropathy model].

  Zhonghua nei ke za zhi 20040801

• Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase.

  Bioorganic & medicinal chemistry letters 20040705

• The impact of third-generation beta-blocker antihypertensive treatment on endothelial function and the prothrombotic state: effects of smoking.

  American journal of hypertension 20040701

• Ocular axial length in homocystinuria patients with and without ocular changes: effects of early treatment and biochemical control.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20040601

• Nutrition and metabolism.

  Current opinion in lipidology 20040401

• Plasma homocysteine concentrations in children of families with proven myocardial infarction before the age of 55 years.

  Acta paediatrica (Oslo, Norway : 1992) 20040401

• L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells.

  Free radical biology & medicine 20040301

• Elevated plasma total homocysteine in centenarians.

  Clinical chemistry and laboratory medicine 20040301

• Homocysteine and left ventricular hypertrophy in children with chronic renal failure.

  Pediatric nephrology (Berlin, Germany) 20040201

• Cerebral sinus thrombosis in a young adult with activated protein C resistance and homosysteinaemia.

  Hospital medicine (London, England : 1998) 20040201

• Effects of dietary folic acid supplementation on cerebrovascular endothelial dysfunction in rats with induced hyperhomocysteinemia.

  Brain research 20040123

• Copper-mediated LDL oxidation by homocysteine and related compounds depends largely on copper ligation.

  Biochimica et biophysica acta 20040120

• Homocysteine increases methionine synthase mRNA level in Caco-2 cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101

• Alzheimer's disease: a progress report, Part II. The continuing search for treatments and persistent hopes for prevention.

  The Harvard mental health letter 20031201

• Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial.

  Journal of internal medicine 20031101

• Homocysteine, Marfan syndrome and arteriosclerosis.

  European heart journal 20031101

• Homocysteine levels in polymyalgia rheumatica and giant cell arteritis: influence of corticosteroid therapy.

  Rheumatology (Oxford, England) 20030901

• Effect of homocysteine on cytokine production by human endothelial cells and monocytes.

  Annals of clinical biochemistry 20030901

• Comparison of isotope dilution mass spectrometry methods for the determination of total homocysteine in plasma and serum.

  Analytical chemistry 20030901

• Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine.

  Circulation 20030826

• Hyperhomocysteinemia in cerebral vein thrombosis.

  Blood 20030815

• Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells.

  Human molecular genetics 20030715

• Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency.

  The New England journal of medicine 20030703

• Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification.

  Stroke 20030601

• Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice.

  Atherosclerosis 20030601

• Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.

  Atherosclerosis 20030601

• Homocysteine strongly enhances metal-catalyzed LDL oxidation in the presence of cystine and cysteine.

  Atherosclerosis 20030501

• Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine.

  Human reproduction (Oxford, England) 20030401

• Homocysteine during the menstrual cycle in depressive women.

  European journal of clinical investigation 20030301

• A simultaneous liquid chromatography/mass spectrometric assay of glutathione, cysteine, homocysteine and their disulfides in biological samples.

  Journal of pharmaceutical and biomedical analysis 20030226

• Effects of cytidine 5'-diphosphocholine on plasma homocysteine levels in rat.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

• A randomized placebo-controlled study of the effect of transdermal vs. oral estradiol with or without gestodene on homocysteine levels.

  Fertility and sterility 20030201

• Diabetic ketoacidosis promotes a prothrombotic state.

  Endocrine research 20030201

• Genetics of hyperhomocysteinaemia in cardiovascular disease.

  Annals of clinical biochemistry 20030101

• [Prevention of stroke].

  Wiener medizinische Wochenschrift (1946) 20030101

• Cardiovascular risk in peritoneal dialysis.

  Contributions to nephrology 20030101

• Classical homocystinuria: vascular risk and its prevention.

  Journal of inherited metabolic disease 20030101

• 2 minute non-invasive screening for cardio-vascular diseases: relative limitation of C-Reactive Protein compared with more sensitive L-Homocystine as cardio-vascular risk factors; safe and effective treatment using the selective drug uptake enhancement method.

  Acupuncture & electro-therapeutics research 20030101

• Biochemical risk factors in angiographically established stenosis of cerebral arteries.

  Croatian medical journal 20021201

• [Arguments in favor of a link between hyperhomocysteinemia and dementia].

  Presse medicale (Paris, France : 1983) 20021130

• Metabolic response of normal and malignant tissue to acute and chronic methionine stress in athymic mice bearing human glial tumor xenografts.

  Chemical research in toxicology 20021101

• Hyperhomocysteinemia in Japanese patients with convalescent stage ischemic stroke: effect of combined therapy with folic acid and mecobalamine.

  Journal of the neurological sciences 20021015

• Two cases of benign methylmalonic aciduria detected during a pilot study of neonatal urine screening.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020825

• Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency.

  Metabolism: clinical and experimental 20020801

• Reproductive fitness in maternal homocystinuria due to cystathionine beta-synthase deficiency.

  Journal of inherited metabolic disease 20020801

• Effects of homocysteine thiol group on fibrin networks: another possible mechanism of harm.

  Thrombosis research 20020715

• Endothelial dysfunction relates to folate status in children and adolescents with type 1 diabetes.

  Diabetes 20020701

• Early-onset cobalamin C/D deficiency: epilepsy and electroencephalographic features.

  Epilepsia 20020601

• Validation of homocyst(e)ine-lowering treatment in the era of folic acid fortification of cereal grains.

  Arteriosclerosis, thrombosis, and vascular biology 20020601

• Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria.

  Journal of inherited metabolic disease 20020501

• Plasma free amino acids in Taiwan Chinese: the effect of age.

  Clinical chemistry and laboratory medicine 20020401

• Homocystine solubility and vascular disease.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020301

• Changes in plasma homocyst(e)ine in the acute phase after stroke.

  Stroke 20020201

• Sulfur in human nutrition and applications in medicine.

  Alternative medicine review : a journal of clinical therapeutic 20020201

• Production of selenohomocystine as an antibiotic by a marine Bacillus sp. no. 14 with selenomethionine resistance.

  The Journal of antibiotics 20020201

• Vitamin B12 and folate after 5-12 years of continent ileal urostomy (Kock reservoir) in children and adolescents.

  European urology 20020201

• [Inhibition on the endocytosis of early visceral yolk sac induced by homocysteine in rats].

  Wei sheng yan jiu = Journal of hygiene research 20020201

• Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates.

  Pharmacology & toxicology 20020101

• Dextromethorphan is effective in the treatment of subacute methotrexate neurotoxicity.

  Pediatric hematology and oncology 20020101

• [Comparison of plasma total homocysteine determinations in 9 French hospital laboratories by using 6 different methods].

  Annales de biologie clinique 20020101

• Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulation.

  The Journal of biological chemistry 20011214

• Ocular findings among patients with late-diagnosed or poorly controlled homocystinuria compared with a screened, well-controlled population.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20011001

• Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia.

  Atherosclerosis 20010901

• Albumin thiolate anion is an intermediate in the formation of albumin-S-S-homocysteine.

  The Journal of biological chemistry 20010810

• Folate status among patients with non-small cell lung cancer: a case-control study.

  Journal of surgical oncology 20010801

• The intellectual abilities of early-treated individuals with pyridoxine-nonresponsive homocystinuria due to cystathionine beta-synthase deficiency.

  Journal of inherited metabolic disease 20010801

• [Homocysteine--a risk factor for atherosclerosis].

  Orvosi hetilap 20010708

• Influence of metabolic control on growth in homocystinuria due to cystathionine B-synthase deficiency.

  Pediatric research 20010601

• Reduced total plasma homocyst(e)ine in children and adolescents with type 1 diabetes.

  The Journal of pediatrics 20010601

• Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.

  Cancer research 20010515

• Effects of growth hormone (GH) administration on homocyst(e)ine levels in men with GH deficiency: a randomized controlled trial.

  The Journal of clinical endocrinology and metabolism 20010401

• The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.

  The Journal of biological chemistry 20010309

• Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection.

  Stroke 20010301

• [Homocysteine and hyperhomocysteinemia].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010301

• Homocyst(e)ine, oxidative stress, and endothelium function in uremic patients.

  Kidney international. Supplement 20010201

• Vitamin Intervention for Stroke Prevention (VISP) trial: rationale and design.

  Neuroepidemiology 20010201

• Inhibition of K+ currents by homocysteine in rat ventricular myocytes.

  Journal of cardiovascular electrophysiology 20010201

• [Homocysteine metabolism and risk of cardiovascular diseases: importance of the nutritional status on folic acid, vitamins B6 and B12].

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20010101

• Short-term folic acid supplementation induces variable and paradoxical changes in plasma homocyst(e)ine concentrations.

  Lipids 20010101

• Patients with atherosclerotic vascular disease: how low should plasma homocyst(e)ine levels go?

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101