871362-31-1 | Ctep

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$30.00	$21.00
5mg	98%	in stock	$65.00	$45.00
10mg	98%	in stock	$86.00	$60.00
25mg	98%	in stock	$139.00	$97.00
50mg	98%	in stock	$220.00	$154.00

Description

• Catalog Number: AH85271
• Chemical Name: Ctep
• CAS Number: 871362-31-1
• Molecular Formula: C19H13ClF3N3O
• Molecular Weight: 391.7742
• MDL Number: MFCD22665726
• SMILES: Clc1nccc(c1)C#Cc1nc(n(c1C)c1ccc(cc1)OC(F)(F)F)C

Computed Properties

• Complexity: 568
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• XLogP3: 5.6

Literature

• Metabotropic glutamate receptor 5 negative allosteric modulators: discovery of 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (basimglurant, RO4917523), a promising novel medicine for psychiatric diseases.

  Journal of medicinal chemistry 20150212

• Fragile X syndrome therapeutics S(C)TEP through the developmental window.

  Neuron 20120412

• CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor.

  The Journal of pharmacology and experimental therapeutics 20111101