872511-34-7 | Nvp-BGJ398

Packsize	Purity	Availability	Price	Discounted Price
1mg	99+%	in stock	$13.00	$9.00
5mg	99+%	in stock	$33.00	$23.00
10mg	99+%	in stock	$47.00	$33.00
100mg	98%	in stock	$325.00	$228.00
250mg	98%	in stock	$558.00	$391.00

Description

• Catalog Number: AH85355
• Chemical Name: Nvp-BGJ398
• CAS Number: 872511-34-7
• Molecular Formula: C26H31Cl2N7O3
• Molecular Weight: 560.4754
• MDL Number: MFCD22123241
• SMILES: CCN1CCN(CC1)c1ccc(cc1)Nc1ncnc(c1)N(C(=O)Nc1c(Cl)c(OC)cc(c1Cl)OC)C

Computed Properties

• Complexity: 724
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 38
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 4.7

Literature

• Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.

  Journal of medicinal chemistry 20111027