876919-08-3 | Methyl 3-fluoroisonicotinate

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$5.00	$4.00
250mg	98%	in stock	$6.00	$5.00
1g	98%	in stock	$16.00	$12.00
5g	98%	in stock	$73.00	$52.00
10g	98%	in stock	$106.00	$75.00
25g	98%	in stock	$225.00	$158.00

Description

• Catalog Number: AH92479
• Chemical Name: Methyl 3-fluoroisonicotinate
• CAS Number: 876919-08-3
• Molecular Formula: C7H6FNO2
• Molecular Weight: 155.1264
• MDL Number: MFCD11045048
• SMILES: COC(=O)c1ccncc1F

Computed Properties

• Complexity: 151
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• XLogP3: 0.8

Upstream Synthesis Route

Methyl 3-fluoroisonicotinate is a versatile compound widely utilized in chemical synthesis for various applications. In organic chemistry, it serves as a key building block in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. Due to its unique structure and reactivity, the compound is particularly valuable in the development of novel drug candidates and bioactive molecules.One of the prominent uses of Methyl 3-fluoroisonicotinate is in the synthesis of heterocyclic compounds, especially in the formation of fused ring systems. By incorporating this molecule into different synthetic pathways, chemists can access a diverse range of complex structures with potential biological activities. The presence of the fluoro group further enhances the compound's pharmacological properties, making it an attractive scaffold for drug discovery.Additionally, Methyl 3-fluoroisonicotinate plays a crucial role in the synthesis of fluorinated organic compounds, which are of interest in medicinal chemistry and material science. The introduction of fluorine atoms can significantly impact the physicochemical properties of the resulting molecules, leading to improved drug potency, metabolic stability, and selectivity. This makes the compound a valuable tool for researchers aiming to modify bioactive molecules for specific applications.In summary, the application of Methyl 3-fluoroisonicotinate in chemical synthesis offers a wide range of possibilities for the creation of innovative molecules with potential therapeutic benefits. Its strategic use in building complex structures and introducing fluorine functionalities highlights its importance in the pursuit of new drug candidates and functional materials.

Literature

• A simple synthetic route to methyl 3-fluoropyridine-4-carboxylate by nucleophilic aromatic substitution.

  Molecules (Basel, Switzerland) 20060225