879-65-2 | 2-Quinoxalinecarboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$15.00	$11.00
25g	98%	in stock	$40.00	$28.00
100g	98%	in stock	$150.00	$105.00
500g	98%	in stock	$682.00	$478.00

Description

• Catalog Number: AB63001
• Chemical Name: 2-Quinoxalinecarboxylic acid
• CAS Number: 879-65-2
• Molecular Formula: C9H6N2O2
• Molecular Weight: 174.15614000000002
• MDL Number: MFCD00012334
• SMILES: OC(=O)c1cnc2c(n1)cccc2
• NSC Number: 86873

Computed Properties

• Complexity: 208
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.6

Literature

• Quantum mechanical study of the structure and spectroscopic (FT-IR, FT-Raman, 13C, 1H and UV), NBO and HOMO-LUMO analysis of 2-quinoxaline carboxylic acid.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120615

• Determination of Carbadox and metabolites of Carbadox and Olaquindox in muscle tissue using high performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120115

• Development and validation of an immunochromatographic assay for the rapid detection of quinoxaline-2-carboxylic acid, the major metabolite of carbadox in the edible tissues of pigs.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

• Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20111101

• Quinoxalin-2-carboxamides: synthesis and pharmacological evaluation as serotonin type-3 (5-HT3) receptor antagonists.

  Journal of enzyme inhibition and medicinal chemistry 20111001

• Novel surface molecularly imprinted sol-gel polymer applied to the online solid phase extraction of methyl-3-quinoxaline-2-carboxylic acid and quinoxaline-2-carboxylic acid from pork muscle.

  Analytical and bioanalytical chemistry 20111001

• Determination of marker residue of Olaquindox in fish tissue by ultra performance liquid chromatography-tandem mass spectrometry.

  Journal of separation science 20110201

• Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics.

  The Journal of antibiotics 20110101

• Design, synthesis and structure-activity relationship of novel quinoxalin-2-carboxamides as 5-HT3 receptor antagonists for the management of depression.

  Bioorganic & medicinal chemistry letters 20101115

• QSAR analysis for quinoxaline-2-carboxylate 1,4-di-N-oxides as anti-mycobacterial agents.

  Journal of molecular graphics & modelling 20090801

• A determinative and confirmatory method for residues of the metabolites of carbadox and olaquindox in porcine tissues.

  Analytica chimica acta 20090401

• Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015

• Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture.

  Biotechnology progress 20080101

• Development of a high-performance liquid chromatography method for the simultaneous quantification of quinoxaline-2-carboxylic acid and methyl-3-quinoxaline-2-carboxylic acid in animal tissues.

  Journal of chromatography. A 20070330

• Identification and stereochemical assignment of the beta-hydroxytryptophan intermediate in the echinomycin biosynthetic pathway.

  Organic letters 20061012

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Effects of cooking and storage on residues of cyadox in chicken muscle.

  Journal of agricultural and food chemistry 20051214

• Development of HPLC methods for the determination of cyadox and its main metabolites in goat tissues.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051201

• Synthesis of new quinoxaline-2-carboxylate 1,4-dioxide derivatives as anti-Mycobacterium tuberculosis agents.

  Journal of medicinal chemistry 20050324

• Confirmation of carbadox and olaquindox metabolites in porcine liver using liquid chromatography-electrospray, tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

• Functional cross-talk between fatty acid synthesis and nonribosomal peptide synthesis in quinoxaline antibiotic-producing streptomycetes.

  The Journal of biological chemistry 20050211

• Quinoxaline-2-carboxylic acid in pigs: criteria to distinguish between the illegal use of carbadox and environmental contamination.

  Food additives and contaminants 20040601

• [Determination of carbadox metabolites, quinoxaline-2-carboxylic acid and desoxycarbadox, in swine muscle and liver by liquid chromatography/mass spectrometry].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040601

• Synthesis and AMPA receptor antagonistic activity of a novel class of quinoxalinecarboxylic acid with a substituted phenyl group at the C-7 position.

  Bioorganic & medicinal chemistry letters 20031020

• Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives.

  Journal of medicinal chemistry 20021205

• Development and validation of an improved method for confirmation of the carbadox metabolite, quinoxaline-2-carboxylic acid, in porcine liver using LC-electrospray MS-MS according to revised EU criteria for veterinary drug residue analysis.

  The Analyst 20020301