883065-90-5 | Bi-78d3

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$42.00	$29.00
5mg	98%	in stock	$151.00	$106.00
10mg	98%	in stock	$276.00	$193.00
25mg	98%	in stock	$587.00	$411.00

Description

• Catalog Number: AD86253
• Chemical Name: Bi-78d3
• CAS Number: 883065-90-5
• Molecular Formula: C13H9N5O5S2
• Molecular Weight: 379.3711
• MDL Number: MFCD01313575
• SMILES: [O-][N+](=O)c1cnc(s1)Sc1n[nH]c(=O)n1c1ccc2c(c1)OCCO2

Computed Properties

• Complexity: 588
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 9
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 2.7

Literature

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3.

  British journal of pharmacology 20120701

• Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors.

  Bioorganic & medicinal chemistry 20100115

• Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase.

  Journal of medicinal chemistry 20090409

• Purification and properties of a periplasmic aminoendopeptidase from Escherichia coli.

  European journal of biochemistry 19751215