89-77-0 | 2-Amino-4-chlorobenzoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$16.00	$11.00
25g	95%	in stock	$20.00	$14.00
100g	95%	in stock	$53.00	$37.00
500g	95%	in stock	$153.00	$107.00

Description

• Catalog Number: AB43773
• Chemical Name: 2-Amino-4-chlorobenzoic acid
• CAS Number: 89-77-0
• Molecular Formula: C7H6ClNO2
• Molecular Weight: 171.581
• MDL Number: MFCD00007778
• SMILES: Clc1ccc(c(c1)N)C(=O)O
• NSC Number: 17188

Computed Properties

• Complexity: 163
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.6

Upstream Synthesis Route

2-Amino-4-chlorobenzoic acid, also known as anthranilic acid, serves a crucial role in chemical synthesis as a versatile building block. Due to its amino and carboxylic acid functional groups, this compound can participate in various reactions to yield diverse compounds of interest. In organic synthesis, 2-Amino-4-chlorobenzoic acid is commonly utilized for the preparation of pharmaceuticals, dyes, and agrochemicals. Its reactivity allows for the introduction of different substituents at the amine or carboxylic acid positions, enabling the synthesis of structurally complex molecules. Additionally, 2-Amino-4-chlorobenzoic acid can undergo acylation, sulfonylation, and other derivatization reactions to modify its properties for specific applications in drug discovery, materials science, and other fields.

Literature

• (E)-(2-Chloro-benzyl-idene)amino 2-amino-4-chloro-benzoate.

  Acta crystallographica. Section E, Structure reports online 20120301

• 2-Amino-4-chloro-benzoic acid.

  Acta crystallographica. Section E, Structure reports online 20110101

• Bis(2-amino-4-chloro-benzoato)triphenyl-anti-mony(V).

  Acta crystallographica. Section E, Structure reports online 20091101

• Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.

  Microbiology (Reading, England) 20090901

• Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

  PLoS pathogens 20070901

• Mononuclear metal complexes of organic carboxylic acid derivatives: synthesis, spectroscopic characterization, thermal investigation and antimicrobial activity.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601