892-48-8 | 5'-Chloro-5'-deoxyadenosine

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$6.00	$5.00
5g	96%	in stock	$8.00	$6.00
10g	96%	in stock	$14.00	$10.00
25g	96%	in stock	$33.00	$24.00
100g	96%	in stock	$119.00	$84.00

Description

• Catalog Number: AB89225
• Chemical Name: 5'-Chloro-5'-deoxyadenosine
• CAS Number: 892-48-8
• Molecular Formula: C10H12ClN5O3
• Molecular Weight: 285.68698
• MDL Number: MFCD00049038
• SMILES: ClC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N

Computed Properties

• Complexity: 338
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2
• XLogP3: -0.3

Literature

• S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.

  Bioorganic & medicinal chemistry letters 20120615

• Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.

  Proceedings of the National Academy of Sciences of the United States of America 20090728

• Activation and inhibition of DNA methyltransferases by S-adenosyl-L-homocysteine analogues.

  Bioorganic & medicinal chemistry 20080301

• Discovery and characterization of a marine bacterial SAM-dependent chlorinase.

  Nature chemical biology 20080101