90-45-9 | 9-Aminoacridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$16.00	$11.00
1g	97%	in stock	$28.00	$19.00
5g	97%	in stock	$45.00	$31.00
10g	97%	in stock	$89.00	$62.00
25g	97%	in stock	$185.00	$129.00
100g	97%	in stock	$572.00	$400.00

Description

• Catalog Number: AH82031
• Chemical Name: 9-Aminoacridine
• CAS Number: 90-45-9
• Molecular Formula: C13H10N2
• Molecular Weight: 194.23189999999997
• MDL Number: MFCD00150520
• SMILES: Nc1c2ccccc2nc2c1cccc2

Computed Properties

• Complexity: 207
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.8

Literature

• Disruption of DNA Damage-Response by Propyl Gallate and 9-Aminoacridine.

  Toxicological sciences : an official journal of the Society of Toxicology 20160601

• Inhibition of the mutagenic effects of N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine by indenopyridines in the Salmonella typhimurium tester strain 1537 and E. coli.

  Drug and chemical toxicology 20141001

• Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

  Scientific reports 20140101

• Studies on the inclusion behavior of 9-Aminoacridine into cyclodextrins: spectroscopic and theoretical evidences.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20130215

• Spectroscopic investigation on the interaction of 9-aminoacridine with certain dyes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901

• Promethazine inhibits NMDA-induced currents - new pharmacological aspects of an old drug.

  Neuropharmacology 20120801

• Comparison of cardiolipins from Drosophila strains with mutations in putative remodeling enzymes.

  Chemistry and physics of lipids 20120701

• Investigations on photoinduced interaction of 9-aminoacridine with certain catechols and rutin.

  Journal of fluorescence 20120701

• Lipidomics of intact mitochondria by MALDI-TOF/MS.

  Journal of lipid research 20120701

• Antigenotoxic properties of two newly synthesized β-aminoketones against N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine-induced mutagenesis.

  Journal of biochemical and molecular toxicology 20120701

• Raman spectroscopy and laser desorption mass spectrometry for minimal destructive forensic analysis of black and color inkjet printed documents.

  Forensic science international 20120610

• 9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.

  Cancer chemotherapy and pharmacology 20120601

• Photoacoustic and luminescence characterization of nitrogen heterocyclic aromatic UV-MALDI matrices in solution.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

• 9-Amino-acridinium bis-(pyridine-2,6-dicarboxyl-ato-κ(3)O(2),N,O(6))ferrate(III) tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20120601

• Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.

  International journal of cancer 20120401

• Synthesis and biological evaluation of acridine derivatives as antimalarial agents.

  ChemMedChem 20120401

• The in vitro toxicology of Swedish snus.

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• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato)zincate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20120401

• MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix.

  Analytical chemistry 20120306

• Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition.

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• Pharmacokinetics and metabolite identification of a novel VEGFR-2 and Src dual inhibitor 6-chloro-2-methoxy-N-(2-methoxybenzyl) acridin-9-amine in rats by liquid chromatography tandem mass spectrometry.

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• Studying the interactions of a platinum(II) 9-aminoacridine complex with proteins and oligonucleotides by ESI-TOF MS.

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• An investigation on the fluorescence quenching of 9-aminoacridine by certain pyrimidines.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

• Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.

  American journal of physiology. Cell physiology 20111001

• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)manganate(II) trihydrate.

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• Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.

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• DNA cleavage activity of Fe(II)N4Py under photo irradiation in the presence of 1,8-naphthalimide and 9-aminoacridine: unexpected effects of reactive oxygen species scavengers.

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• Protective effects of methanol extracts from Cladonia rangiformis and Umbilicaria vellea against known mutagens sodium azide and 9-aminoacridine.

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• Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

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• The sequence selectivity of DNA-targeted 9-aminoacridine cisplatin analogues in a telomere-containing DNA sequence.

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• Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice.

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• Microscale MALDI imaging of outer-layer lipids in intact egg chambers from Drosophila melanogaster.

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• Sphingomyelin is more sensitively detectable as a negative ion than phosphatidylcholine: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study using 9-aminoacridine (9-AA) as matrix.

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• Significant sensitivity improvements by matrix optimization: a MALDI-TOF mass spectrometric study of lipids from hen egg yolk.

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• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)nickelate(II) trihydrate.

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• A phase I trial of amsalog (CI-921) administered by intravenous infusion using a 5-day schedule.

  Cancer chemotherapy and pharmacology 20010401

• Surface-enhanced Raman and steady fluorescence study of interaction between antitumoral drug 9-aminoacridine and trypsin-like protease related to metastasis processes, guanidinobenzoatase.

  Biopolymers 20010101

• [Extracellular protein of propionic acid bacteria inhibits induced mutation in strains of Salmonella typhimurium].

  Mikrobiologiia 20010101

• Effects of slow clinorotation on lipid contents and proton permeability of thylakoid membranes of pea chloroplasts.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101

• [Synthesis and antibacterial activity of the new 9-aminoacridine, 10,11-dihydro-5H-dibenzo[b,f]azepine, polyfluoro 5,6-dihydro-1,3,5-oxadiazine derivatives].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• Inhibitors of human immunodeficiency virus integrase.

  Proceedings of the National Academy of Sciences of the United States of America 19930315

• HIV-1 neutralization and tumor cell proliferation inhibition in vitro by simplified analogues of pyrido[4,3,2-mn]thiazolo[5,4-b]acridine marine alkaloids.

  Journal of medicinal chemistry 19920724