91296-87-6 | Sarafloxacin hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$16.00	$11.00
100mg	95%	in stock	$20.00	$14.00
1g	95%	in stock	$33.00	$23.00
5g	95%	in stock	$70.00	$49.00
25g	95%	in stock	$192.00	$134.00
100g	95%	in stock	$738.00	$516.00

Description

• Catalog Number: AI61097
• Chemical Name: Sarafloxacin hydrochloride
• CAS Number: 91296-87-6
• Molecular Formula: C20H18ClF2N3O3
• Molecular Weight: 421.82502639999984
• MDL Number: MFCD24539194
• SMILES: Fc1ccc(cc1)n1cc(C(=O)O)c(=O)c2c1cc(N1CCNCC1)c(c2)F.Cl
• NSC Number: 758956

Computed Properties

• Complexity: 645
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 29
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3

Literature

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  Pharmaceutical statistics 20120101

• Persistence of the fluoroquinolone antibiotic difloxacin in soil and lacking effects on nitrogen turnover.

  Journal of environmental quality 20120101

• Comparison of different sample treatments for the analysis of quinolones in milk by capillary-liquid chromatography with laser induced fluorescence detection.

  Journal of chromatography. A 20110729

• Tobacco-associated pulmonary vascular dysfunction in smokers: role of the ET-1 pathway.

  American journal of physiology. Lung cellular and molecular physiology 20110601

• Bufferized solvent extraction and HPLC fluorometric detection method for sarafloxacin in pig and chicken muscles.

  Biomedical chromatography : BMC 20110301

• Effects of fluoroquinolones on CYP4501A and 3A in male broilers.

  Research in veterinary science 20110201

• Plasma disposition and tissue depletion of difloxacin and its metabolite sarafloxacin in the food producing animals, chickens for fattening.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110201

• Determination of ciprofloxacin in human plasma using high-performance liquid chromatography coupled with fluorescence detection: application to a population pharmacokinetics study in children with severe malnutrition.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Simultaneous determination of quinolones for veterinary use by high-performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

• In vitro residual anti-bacterial activity of difloxacin, sarafloxacin and their photoproducts after photolysis in water.

  Environmental pollution (Barking, Essex : 1987) 20091001

• Photolysis of difloxacin and sarafloxacin in aqueous systems.

  Chemosphere 20091001

• Quantification of danofloxacin and difloxacin in chicken tissues in the presence of sarafloxacin as interference.

  Journal of agricultural and food chemistry 20090909

• Quantitation and identity confirmation of residues of quinolones in tilapia fillets by LC-ESI-MS-MS QToF.

  Analytical and bioanalytical chemistry 20090801

• Metabolism and excretion kinetics of 14C-labeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites.

  Environmental research 20090401

• Primary photoprocesses in a fluoroquinolone antibiotic sarafloxacin.

  Photochemistry and photobiology 20090101

• Development and validation of a solid-phase extraction method coupled to liquid chromatography with fluorescence detection for the determination of fluoroquinolone residues in powdered infant formulae. Application to the analysis of samples from the Spanish and Latin American market.

  Journal of chromatography. A 20081031

• Endotoxemic pulmonary hypertension is largely mediated by endothelin-induced venous constriction.

  Intensive care medicine 20080501

• [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20070701

• Simultaneous multiresidue determination of tetracyclines and fluoroquinolones in catfish muscle using high performance liquid chromatography with fluorescence detection.

  Analytica chimica acta 20070314

• Development of a new sample pretreatment procedure based on pressurized liquid extraction for the determination of fluoroquinolone residues in table eggs.

  Journal of chromatography. A 20070126

• Vibrational spectroscopic characterization of fluoroquinolones.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501

• [Simultaneous determination of four fluoroquinolone residues in edible chicken tissues by reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20050501

• Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells.

  Journal of drug targeting 20050401

• Multiresidue determination of fluoroquinolones in shrimp by liquid chromatography-fluorescence-mass spectrometry.

  Journal of AOAC International 20050101

• Multiresidue method for simultaneous determination of ten quinolone antibacterial residues in multimatrix/multispecies animal tissues by liquid chromatography with fluorescence detection: single laboratory validation study.

  Journal of AOAC International 20050101

• Multiresidue determination of eleven quinolones in milk by liquid chromatography with fluorescence detection.

  Journal of AOAC International 20050101

• [Simultaneous determination of quinolones in foods by LC/MS/MS].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001

• Heat-induced formulation inhomogeneity of a three-component suspension.

  Drug development and industrial pharmacy 20040801

• High-performance liquid chromatographic method with fluorescence detection for the screening and quantification of oxolinic acid, flumequine and sarafloxacin in fish.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125

• Liquid chromatographic determination of fluoroquinolones in egg albumen and egg yolk of laying hens using fluorometric detection.

  Journal of agricultural and food chemistry 20020731

• Efficacy of sarafloxacin in broilers after experimental infection with Escherichia coli.

  Veterinary research communications 20020601

• Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020215

• Development of a topical suspension containing three active ingredients.

  Drug development and industrial pharmacy 20020101

• Pharmacokinetics of sarafloxacin in pigs and broilers following intravenous, intramuscular, and oral single-dose applications.

  Journal of veterinary pharmacology and therapeutics 20011001

• Determination of fluoroquinolones in serum using an on-line clean-up column coupled to high-performance immunoaffinity-reversed-phase liquid chromatography.

  Journal of chromatography. B, Biomedical sciences and applications 20010415

• Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus.

  Journal of industrial microbiology & biotechnology 20010301

• In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline.

  Avian diseases 20010101

• FDA withdraws approval of two poultry drugs.

  FDA consumer 20010101

• In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.

  The Journal of antimicrobial chemotherapy 19870501