92-61-5 | Scopoletin

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$10.00	$7.00
10mg	97%	in stock	$36.00	$25.00
25mg	97%	in stock	$62.00	$44.00
100mg	97%	in stock	$69.00	$48.00
250mg	97%	in stock	$112.00	$78.00
1g	97%	in stock	$283.00	$198.00
5g	97%	in stock	$1,240.00	$868.00

Description

• Catalog Number: AI61616
• Chemical Name: Scopoletin
• CAS Number: 92-61-5
• Molecular Formula: C10H8O4
• Molecular Weight: 192.1681
• MDL Number: MFCD00006872
• SMILES: COc1cc2ccc(=O)oc2cc1O
• NSC Number: 405647

Computed Properties

• Complexity: 261
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.5

Literature

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  Plant physiology 20180501

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  Journal of food protection 20171003

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• Coordinated regulation of scopoletin at adipose tissue-liver axis improved alcohol-induced lipid dysmetabolism and inflammation in rats.

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  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090501

• Influence of the multidrug transporter inhibitors on the activity of Kv1.3 voltage-gated potassium channels.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301

• [Studies on the chemical constituents of the aerial part of Bupleurum chinense (II)].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090301

• Antiosteoporotic activity of anthraquinones from Morinda officinalis on osteoblasts and osteoclasts.

  Molecules (Basel, Switzerland) 20090123

• Coumarinic derivatives show anti-inflammatory effects on alveolar macrophages, but their anti-elastase activity is essential to reduce lung inflammation in vivo.

  International immunopharmacology 20090101

• Extraction of antioxidants from plants using ultrasonic methods and their antioxidant capacity.

  Journal of separation science 20090101

• Antioxidant constituents from Cotoneaster racemiflora.

  Journal of Asian natural products research 20090101

• Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense.

  Journal of Asian natural products research 20090101

• Biological activity of secondary metabolites from Peltostigma guatemalense.

  Natural product research 20090101

• Anticonvulsant Activity of Argyreia speciosa in Mice.

  Indian journal of pharmaceutical sciences 20090101

• Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose.

  Journal of dietary supplements 20090101

• Investigation of biosynthetic pathways to hydroxycoumarins during post-harvest physiological deterioration in Cassava roots by using stable isotope labelling.

  Chembiochem : a European journal of chemical biology 20081215

• In vitro studies demonstrate anticancer activity of an alkaloid of the plant Gelsemium sempervirens.

  Experimental biology and medicine (Maywood, N.J.) 20081201

• Biosynthesis of scopoletin and scopolin in cassava roots during post-harvest physiological deterioration: the E-Z-isomerisation stage.

  Phytochemistry 20081201

• Steroids, alkaloids, and coumarins from Gelsemium sempervirens.

  Planta medica 20081201

• Antimycobacterial butanolides from the root of Lindera akoensis.

  Chemistry & biodiversity 20081201

• Inhibitory effect of macabarterin, a polyoxygenated ellagitannin from Macaranga barteri, on human neutrophil respiratory burst activity.

  Journal of natural products 20081101

• Study of antimalarial activity of chemical constituents from Diospyros quaesita.

  Chemistry & biodiversity 20081101

• [Studies on chemical constituents from twigs of Morus atropurpurea].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101

• alpha-glucosidase inhibitors from Garcinia brevipedicellata (Clusiaceae).

  Chemical & pharmaceutical bulletin 20081001

• [Studies on chemical constituents of Ranunculus japonicus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

• [Studies on chemical constituents from Elaeocarpus sylvestris].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081001

• Scopoletin is biosynthesized via ortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase in Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20080901

• Studies of coumarins from the Chinese drug Qianhu, XXVII: structure of a new simple coumarin glycoside from Bai-Hua Qianhu, Peucedanum praeruptorum.

  Chemical & pharmaceutical bulletin 20080901

• [Studies on chemical constituents from leaves of Vaccinium bracteatum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

• [Four new compounds from the non-polar extract of the plant Amyris brenesii (Rutaceae) from Costa Rica].

  Revista de biologia tropical 20080901

• Simultaneous determination of 13 bioactive compounds in Herba Artemisiae Scopariae (Yin Chen) from different harvest seasons by HPLC-DAD.

  Journal of pharmaceutical and biomedical analysis 20080805

• Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency.

  Journal of enzyme inhibition and medicinal chemistry 20080801

• [Studies on absorption kinetics of scopoletin in rat stomachs and intestines].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801

• Rearranged ent-kauranes from the stems of Tricalysia dubia and their biological activities.

  Journal of natural medicines 20080701

• Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle.

  Journal of experimental botany 20080701

• On the extent and origins of genic novelty in the phylum Nematoda.

  PLoS neglected tropical diseases 20080701

• Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways.

  Basic & clinical pharmacology & toxicology 20080701

• Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells.

  Free radical research 20080701

• Minor compounds from the stem bark of Chinese mangrove associate Catunaregam spinosa.

  Die Pharmazie 20080701

• [Coumarins from branch of Fraxinus sieboldiana and their antioxidative activity].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701

• Anticomplementary principles of a Chinese multiherb remedy for the treatment and prevention of SARS.

  Journal of ethnopharmacology 20080508

• Engineering and kinetic characterisation of two glucosyltransferases from Arabidopsis thaliana.

  Biochimie 20080501

• [Study on chemical constituents in roots and rhizomes of Ligularia duciforms II].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501

• [Studies on chemical constituents of Saussurea laniceps].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501

• A new oxygenated ursane derivative from Canthium multiflorum.

  Planta medica 20080401

• Involvement of limonene hydroperoxides formed after oil gland injury in the induction of defense response against Penicillium digitatum in lemon fruit.

  Journal of agricultural and food chemistry 20080326

• An experimental implementation of chemical subtraction.

  Journal of pharmaceutical and biomedical analysis 20080313

• Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells.

  Bioorganic & medicinal chemistry 20080301

• [Chemical constituents from Hedyotis diffusa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301

• Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae.

  Journal of natural products 20080201

• A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus.

  Archives of pharmacal research 20080101

• Ether-soluble resin glycosides from the roots of Ipomoea batatas.

  Journal of Asian natural products research 20080101

• Effects of auxins on growth and scopoletin accumulation in cell suspension cultures of Angelica archangelica L.

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20080101

• Isolation and identification of antioxidants from Pedilanthus tithymaloides.

  Journal of natural medicines 20080101

• Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Active metabolites from Dunalia spinosa resinous exudates.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Chemodiversity of exudate flavonoids in Cassinia and Ozothamnus (Asteraceae, Gnaphalieae).

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Spectrofluorimetric Estimation of Scopoletin in Evolvulus alsinoides Linn. and Convulvulus pluricaulis Choisy.

  Indian journal of pharmaceutical sciences 20080101

• Pharmacokinetic study of Noni fruit extract.

  Journal of dietary supplements 20080101

• Superoxide radical-scavenging effects from polymorphonuclear leukocytes and toxicity in human cell lines of newly synthesized organic selenium compounds.

  The FEBS journal 20071201

• Antifungal activity of a new phenolic compound from capitulum of a head rot-resistant sunflower genotype.

  Journal of chemical ecology 20071201

• Determination of polyphenol components in herbal medicines by micellar electrokinetic capillary chromatography with Tween 20.

  Talanta 20071115

• Lignans and anthraquinones from the fruits of Morinda citrifolia.

  Natural product research 20071101

• Determination of scopoletin in rat plasma by high performance liquid chromatographic method with UV detection and its application to a pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001

• Effect of scopoletin on lipoprotein lipase activity in 3T3-L1 adipocytes.

  International journal of molecular medicine 20071001

• Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products.

  Journal of agricultural and food chemistry 20070905

• The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site.

  Molecular pharmacology 20070901

• Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida.

  Journal of ethnopharmacology 20070815

• A new C9 nor-isoprenoid glucoside from Rantherium suaveolens.

  Natural product research 20070801

• Isolation and structural elucidation of chemical constituents from the fruits of Morinda citrifolia Linn.

  Archives of pharmacal research 20070801

• [Studies on chemical constituents of Suregada glomerulata II].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

• Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.

  European journal of medicinal chemistry 20070701

• Rare biscoumarins and a chlorogenic acid derivative from Erycibe obtusifolia.

  Phytochemistry 20070701

• [Chemical study on aerial parts of Ligusticum chuanxiong].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701

• Inhibitory effect of 4-methylesculetin on hyaluronan synthesis slows the development of human pancreatic cancer in vitro and in nude mice.

  International journal of cancer 20070615

• [Studies on the chemical constituents of Urtica dioica L. grown in Tibet Autonomous Region].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601

• Lipoxygenase inhibitory constituents of the fruits of noni (Morinda citrifolia) collected in Tahiti.

  Journal of natural products 20070501

• [Chemical constituents from leaves of Morus multicaulis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070401

• Multicolor fluorescence imaging for early detection of the hypersensitive reaction to tobacco mosaic virus.

  Journal of plant physiology 20070301

• Scopoletine as fluorescence probe for determination of protein.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070301

• Lagaspholones A and B: two new jatropholane-type diterpenes from Euphorbia lagascae.

  Organic letters 20070201

• Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IkappaB/NF-kappaB signal cascade in the human mast cell line HMC-1.

  European journal of pharmacology 20070126

• In silico prediction of pregnane X receptor activators by machine learning approaches.

  Molecular pharmacology 20070101

• Fascinating metabolic pools of Pelargonium sidoides and Pelargonium reniforme, traditional and phytomedicinal sources of the herbal medicine Umckaloabo.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20070101

• Dynamics and localization of H2O2 production in elicited plant cells.

  Protoplasma 20070101

• Molecular biology of cantharidin in cancer cells.

  Chinese medicine 20070101

• Phytochemical and antinociceptive properties of Matayba elaeagnoides Radlk. barks.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Development of a rapid and validated method for investigating the metabolism of scoparone in rat using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Determination of active ingredients in mutouhui by capillary electrophoresis with electrochemical detection.

  Journal of capillary electrophoresis and microchip technology 20070101

• Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii.

  Fitoterapia 20061201

• Evaluation of the antithyroid, antioxidative and antihyperglycemic activity of scopoletin from Aegle marmelos leaves in hyperthyroid rats.

  Phytotherapy research : PTR 20061201

• Cytotoxic flavaglines and bisamides from Aglaia edulis.

  Journal of natural products 20061201

• Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes.

  Life sciences 20061019

• [Studies on chemical constituents of Euphorbia sororia].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

• Antioxidant, icthyotoxicity and brine shrimp lethality tests of Magonia glabrata.

  Fitoterapia 20060901

• New constituents from noni (Morinda citrifolia) fruit juice.

  Journal of agricultural and food chemistry 20060823

• A new cytotoxic amide from the stem wood of Hibiscus tiliaceus.

  Planta medica 20060801

• Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity.

  Archives of pharmacal research 20060801

• Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi.

  Planta medica 20060701

• Simultaneous analysis of trans- and cis-isomers of 2-glucosyloxycinnamic acids and coumarin derivatives in Dendrobium thyrsiflorum by high-performance liquid chromatography (HPLC)-photodiode array detection (DAD)-electrospray ionization (ESI)-tandem mass spectrometry (MS).

  Analytica chimica acta 20060630

• Silver activates mast cells through reactive oxygen species production and a thiol-sensitive store-independent Ca2+ influx.

  Free radical biology & medicine 20060601

• [Studies on the chemical constituents in herb of Ranunculus japonicus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601

• Investigations of the Malagasy species Tachiadenus longiflorus Grisebach (Gentianaceae): linking chemical finding and traditional usage.

  Journal of ethnopharmacology 20060524

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Clerodanes and other constituents of Cleidion spiciflorum.

  Phytochemistry 20060501

• Production of three O-methhylated esculetins with Escherichia coli expressing O-methyltransferase from poplar.

  Bioscience, biotechnology, and biochemistry 20060501

• [Studies on chemical constituents in roots of Heracleum rapula].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

• Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia.

  Bioorganic & medicinal chemistry 20060215

• Accumulation of coumarins in Arabidopsis thaliana.

  Phytochemistry 20060201

• Cytotoxic constituents from Solanum lyratum.

  Archives of pharmacal research 20060201

• 5-Methoxypropacin, a novel coumarinolignoid from Protium unifoliolatum.

  Natural product research 20060101

• Antinociceptive properties of coumarins, steroid and dihydrostyryl-2-pyrones from Polygala sabulosa (Polygalaceae) in mice.

  The Journal of pharmacy and pharmacology 20060101

• Tilia cordata Mill. Extracts and scopoletin (isolated compound): differential cell growth effects on lymphocytes.

  Phytotherapy research : PTR 20060101

• The structural elucidation of a novel iridoid derivative from Tachiadenus longiflorus (Gentianaceae) using the LSD programme and quantum chemical computations.

  Phytochemical analysis : PCA 20060101

• Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone.

  BMC complementary and alternative medicine 20060101

• Growth at elevated CO2 concentrations leads to modified profiles of secondary metabolites in tobacco cv. SamsunNN and to increased resistance against infection with potato virus Y.

  Plant, cell & environment 20060101

• Toxicity and synergism in the feeding deterrence of some coumarins on Spodoptera frugiperda Smith (Lepidoptera: Noctuidae).

  Chemistry & biodiversity 20060101

• Evaluation of synthetic polymeric micelles as a stabilization medium for the handling of membrane proteins in pharmaceutical drug discovery.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20060101

• Induction of phytoalexins biosynthesis in orange fruit by the biocontrol yeast Rhodotorula glutinis.

  Communications in agricultural and applied biological sciences 20060101

• Dynamic ultrasound-assisted extraction of polyphenols in tobacco.

  Journal of separation science 20051201

• A new cytotoxic daphnane diterpenoid, rediocide G, from Trigonostemon reidioides.

  Chemical & pharmaceutical bulletin 20051001

• HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract.

  Magnetic resonance in chemistry : MRC 20050901

• Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases.

  Drug metabolism and disposition: the biological fate of chemicals 20050701

• Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kappaB and caspase-3.

  Life sciences 20050701

• A labdane diterpene glucoside from the rhizomes of Curcuma mangga.

  Journal of natural products 20050701

• Inhibitory effect of coumarins from Weigela subsessilis on low density lipoprotein oxidation.

  Biological & pharmaceutical bulletin 20050601

• Purification and characterization of a cationic peroxidase Cs in Raphanus sativus.

  Journal of plant physiology 20050601

• [Effect of caffeic acid, seopoletin and scutellarin on rat retinal neurons in vitro].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

• Anthraquinones from Hedyotis capitellata.

  Phytochemistry 20050501

• Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits.

  Journal of agricultural and food chemistry 20050420

• Simultaneous determination of active ingredients in Erigeron breviscapus (Vant.) Hand-Mazz. by capillary electrophoresis with electrochemical detection.

  Journal of pharmaceutical and biomedical analysis 20050309

• Acylperoxylated and seco-mexicanolides from stems of Khaya anthotheca.

  Journal of natural products 20050301

• Total synthesis and biological activity of 13,14-dehydro-12-oxo-phytodienoic acids (deoxy-J1-phytoprostanes).

  Chembiochem : a European journal of chemical biology 20050201

• Hypouricemic action of scopoletin arising from xanthine oxidase inhibition and uricosuric activity.

  Planta medica 20050201

• Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida.

  Phytotherapy research : PTR 20050201

• B1-phytoprostanes trigger plant defense and detoxification responses.

  Plant physiology 20050101

• [Determination of scopoletin and umbelliferone contents in Saussurea medusa Maxim by high-performance liquid chromatography].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101

• Comparison of cytotoxicity of cysteine and homocysteine for renal epithelial cells.

  Nephron. Experimental nephrology 20050101

• A new antipsychotic effective neolignan from Firmiana simplex.

  Archives of pharmacal research 20050101

• Morning glory systemically accumulates scopoletin and scopolin after interaction with Fusarium oxysporum.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

• Combination of extractive solvent addition and immobilization culture for continuous production of scopoletin by tobacco cells.

  Biotechnology progress 20050101

• Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene.

  Journal of biomedicine & biotechnology 20050101

• Biological and physical approaches to improve induced resistance against green mold of stored citrus fruit.

  Communications in agricultural and applied biological sciences 20050101

• The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific, and may involve both monomers.

  Biochemical pharmacology 20041215

• Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products.

  Journal of medicinal chemistry 20041202

• Characterization of cigarette tobacco by direct electrospray ionization-ion trap mass spectrometry (ESI-ITMS) analysis of the aqueous extract--a novel and simple approach.

  Journal of agricultural and food chemistry 20041201

• Beta-1,3 glucan sulfate, but not beta-1,3 glucan, induces the salicylic acid signaling pathway in tobacco and Arabidopsis.

  The Plant cell 20041101

• Antiinflammatory activity of Synurus deltoides.

  Phytotherapy research : PTR 20041101

• Oxidative stress responses during cassava post-harvest physiological deterioration.

  Plant molecular biology 20041101

• A new sesquiterpene lactone from Artemisia rubripes nakai.

  Archives of pharmacal research 20041001

• Oxidative DNA damage induced by a hydroperoxide derivative of cyclophosphamide.

  Free radical biology & medicine 20040915

• Cytotoxic constituents of roots of Chaerophyllum hirsutum.

  Journal of natural products 20040901

• A coumarin from Mallotus resinosus that mediates DNA cleavage.

  Journal of natural products 20040901

• Umbelliferone released from hairy root cultures of Pharbitis nil treated with copper sulfate and its subsequent glucosylation.

  Bioscience, biotechnology, and biochemistry 20040901

• Nor-ent-kaurane diterpenes and hydroxylactones from Antennaria geyeri and Anaphalis margaritacea.

  Phytochemistry 20040901

• Phenylpropanoids, phenylalanine ammonia lyase and peroxidases in elicitor-challenged cassava (Manihot esculenta) suspension cells and leaves.

  Annals of botany 20040701

• Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia.

  Journal of natural products 20040701

• Scopoletin suppresses pro-inflammatory cytokines and PGE2 from LPS-stimulated cell line, RAW 264.7 cells.

  Fitoterapia 20040601

• Constituents of Carapa guianensis Aubl. (Meliaceae).

  Die Pharmazie 20040601

• Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase.

  Bioorganic & medicinal chemistry letters 20040503

• [Study on constituents from Neonauclea griffithii].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040501

• An active and water-soluble truncation mutant of the human UDP-glucuronosyltransferase 1A9.

  Molecular pharmacology 20040401

• Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin.

  Diabetologia 20040401

• Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru.

  Journal of natural products 20040301

• Potential cancer chemopreventive constituents of the leaves of Macaranga triloba.

  Phytochemistry 20040201

• Agrobacterium tumefaciens AK-6b gene modulates phenolic compound metabolism in tobacco.

  Phytochemistry 20040101

• Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity.

  Phytotherapy research : PTR 20040101

• Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel.

  Archives of pharmacal research 20040101

• Secondary metabolite content in Fabiana imbricata plants and in vitro cultures.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Over-expression of a scopoletin glucosyltransferase in Nicotiana tabacum leads to precocious lesion formation during the hypersensitive response to tobacco mosaic virus but does not affect virus resistance.

  Plant molecular biology 20040101

• Influence of distillation system, oak wood type, and aging time on composition of cider brandy in phenolic and furanic compounds.

  Journal of agricultural and food chemistry 20031231

• Directed immobilization of nucleic acids at ultramicroelectrodes using a novel electro-deposited polymer.

  Biosensors & bioelectronics 20031230

• Fc epsilon RI signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals.

  Journal of immunology (Baltimore, Md. : 1950) 20031201

• Antioxidant activity of compounds from the medicinal herb Aster tataricus.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031001

• Glycosides of Atractylodes ovata.

  Chemical & pharmaceutical bulletin 20030901

• High-performance liquid chromatography determination of methionine adenosyltransferase activity using catechol-O-methyltransferase-coupled fluorometric detection.

  Analytical biochemistry 20030801

• Antioxidant properties of scopoletin isolated from Sinomonium acutum.

  Phytotherapy research : PTR 20030801

• Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model.

  Archives of pharmacal research 20030801

• New anthracene derivatives from Coussarea macrophylla.

  Journal of natural products 20030701

• DNA damage by ethylbenzenehydroperoxide formed from carcinogenic ethylbenzene by sunlight irradiation.

  Biochemical and biophysical research communications 20030516

• Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics.

  Drug metabolism and disposition: the biological fate of chemicals 20030501

• Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants.

  The Plant journal : for cell and molecular biology 20030501

• Three new jatrophane-type diterpenes from Euphorbia pubescens.

  Planta medica 20030401

• [Studies on chemical constitutes of Phellinus igniarius].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030401

• Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.

  The Journal of biological chemistry 20030207

• Scaphopetalone and scaphopetalumate, a lignan and a triterpene ester from Scaphopetalum thonneri.

  Phytochemistry 20030201

• Sulfated fucan oligosaccharides elicit defense responses in tobacco and local and systemic resistance against tobacco mosaic virus.

  Molecular plant-microbe interactions : MPMI 20030201

• A polyacetylene and flavonoids from Cirsium rhinoceros.

  Archives of pharmacal research 20030201

• Four guaianolides from Sinodielsia yunnanensis.

  Chemical & pharmaceutical bulletin 20030101

• Molecular cloning and biological activity of alpha-, beta-, and gamma-megaspermin, three elicitins secreted by Phytophthora megasperma H20.

  Plant physiology 20030101

• Study on the determination of polyphenols in tobacco by HPLC coupled with ESI-MS after solid-phase extraction.

  Journal of chromatographic science 20030101

• Potential functional foods in the traditional Maori diet.

  Mutation research 20030101

• [Study on the constituents from Neonauclea sessilifolia].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021201

• Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.

  Journal of natural products 20021101

• [Prediction of eluotropic sequence of solutes in countercurrent chromatography].

  Se pu = Chinese journal of chromatography 20021101

• New pyranonaphthoquinone and pyranonaphthohydroquinone from the roots of Pentas longiflora.

  Journal of natural products 20020901

• Resistance of transgenic tobacco seedlings expressing the Agrobacterium tumefaciens C58-6b gene, to growth-inhibitory levels of cytokinin is associated with elevated IAA levels and activation of phenylpropanoid metabolism.

  Plant & cell physiology 20020801

• Downregulation of a pathogen-responsive tobacco UDP-Glc:phenylpropanoid glucosyltransferase reduces scopoletin glucoside accumulation, enhances oxidative stress, and weakens virus resistance.

  The Plant cell 20020501

• Two new chlorinated amides from Nicotiana glauca R. Graham.

  Die Pharmazie 20020301

• [Studies on immunocompetent constituents of Patrinia scabra Bunge].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020301

• A new coumarin from the stem of Angelica dahurica.

  Archives of pharmacal research 20020201

• Inhibitory effects of phenylpropanoid metabolites on copper-induced protein oxidative modification of mice brain homogenate, in vitro.

  Biological trace element research 20020201

• A pharmacophore for human pregnane X receptor ligands.

  Drug metabolism and disposition: the biological fate of chemicals 20020101

• Isolation of scopoletin from leaves of Hevea brasiliensis and the effect of scopoletin on pathogens of H. brasiliensis.

  Mycopathologia 20020101

• Generation of reactive oxygen species in the enzymatic reduction of PbCrO4 and related DNA damage.

  Molecular and cellular biochemistry 20020101

• Benzothiadiazole Activates Resistance in Sunflower (Helianthus annuus) to the Root-Parasitic Weed Orobanche cuman.

  Phytopathology 20020101

• Purification and characterization of a cationic isoperoxidase from scented-geranium.

  Phytochemistry 20011101

• Phenolic compounds with anti-inflammatory activity from Eupatorium buniifolium.

  Planta medica 20011101

• [Determination of polyphenols in tobacco by solid phase extraction and high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20011101

• Intracellular calcium mobilization as a target for the spasmolytic action of scopoletin.

  Planta medica 20011001

• DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria.

  Journal of neurochemistry 20011001

• Effect of scopoletin on PC3 cell proliferation and apoptosis.

  Acta pharmacologica Sinica 20011001

• Cytotoxic and novel compounds from Solanum indicum.

  Journal of natural products 20010901

• Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus.

  Journal of natural products 20010901

• Quassinoids from Eurycoma harmandiana.

  Phytochemistry 20010801

• Gliotoxin induces apoptosis in cultured macrophages via production of reactive oxygen species and cytochrome c release without mitochondrial depolarization.

  Free radical research 20010701

• Variations in the estimation of the contribution of environmental tobacco smoke (ETS) to respirable (< or = 5 microns) indoor air particulates obtained by the use of different analytical methods.

  Journal of environmental monitoring : JEM 20010601

• Cr (VI) induces cell growth arrest through hydrogen peroxide-mediated reactions.

  Molecular and cellular biochemistry 20010601

• Identification and determination of active components in Angelica dahurica Benth and its medicinal preparation by capillary electrophoresis.

  Talanta 20010530

• Capillary electrophoretic determination of the constituents of Artemisiae Capillaris Herba.

  Journal of chromatography. A 20010316

• Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]methyl]quinoline N-glucuronidation by in vitro and in vivo approaches.

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• [Studies on chemical constituents from the herb of Peucedanum decursivum (Miq.) Maxim].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301

• Mode of action of hot-water dip in reducing decay of lemon fruit.

  Journal of agricultural and food chemistry 20010101

• Terpenoids from Guarea rhophalocarpa.

  Phytochemistry 20010101

• Effects of scopoletin and aflatoxin B1 on bovine hepatic mitochondrial respiratory complexes, 2: a-ketoglutarate cytochrome c and succinate cytochrome c reductases.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

• New indole alkaloids from Sarcocephalus latifolius.

  Natural product letters 20010101

• Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.

  Archives of biochemistry and biophysics 19951001

• Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.

  Drug metabolism and disposition: the biological fate of chemicals 19940101