926908-04-5 | N-Hydroxy-7-(naphthalen-2-ylthio)heptanamide

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%	in stock	$110.00	$77.00
10mg	98%	in stock	$204.00	$143.00
25mg	98%	in stock	$481.00	$337.00

Description

• Catalog Number: AB48488
• Chemical Name: N-Hydroxy-7-(naphthalen-2-ylthio)heptanamide
• CAS Number: 926908-04-5
• Molecular Formula: C17H21NO2S
• Molecular Weight: 303.4191
• MDL Number: MFCD10568146
• SMILES: ONC(=O)CCCCCCSc1ccc2c(c1)cccc2

Computed Properties

• Complexity: 311
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 4.1

Literature

• A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells.

  British journal of pharmacology 20141101

• Potential anti-cancer activity of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo.

  Cancer science 20110201

• N-hydroxy-7-(2-naphthylthio) heptanomide inhibits retinal and choroidal angiogenesis.

  Molecular pharmaceutics 20090101

• Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor.

  Biochemical and biophysical research communications 20070427