931706-15-9 | Ppq-102

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$16.00	$11.00
5mg	99%	in stock	$33.00	$23.00
10mg	99%	in stock	$40.00	$28.00
25mg	99%	in stock	$48.00	$34.00
50mg	99%	in stock	$82.00	$57.00
100mg	99%	in stock	$138.00	$97.00
250mg	99%	in stock	$234.00	$164.00

Description

• Catalog Number: AH85381
• Chemical Name: Ppq-102
• CAS Number: 931706-15-9
• Molecular Formula: C26H22N4O3
• Molecular Weight: 438.4778799999999
• MDL Number: MFCD14824240
• SMILES: Cc1ccc(o1)C1Nc2ccccc2-n2c1c1c(c2c2ccccc2)c(=O)n(c(=O)n1C)C

Computed Properties

• Complexity: 786
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: 3.7

Literature

• Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.

  Journal of medicinal chemistry 20110811

• Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus.

  Bioorganic & medicinal chemistry letters 20100301

• Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model.

  Journal of medicinal chemistry 20091022