933-67-5 | 7-Methylindole

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$16.00	$11.00
5g	97%	in stock	$17.00	$12.00
10g	97%	in stock	$33.00	$23.00
25g	97%	in stock	$58.00	$40.00
500g	97%	in stock	$1,131.00	$792.00

Description

• Catalog Number: AC84590
• Chemical Name: 7-Methylindole
• CAS Number: 933-67-5
• Molecular Formula: C9H9N
• Molecular Weight: 131.17445999999998
• MDL Number: MFCD00005684
• SMILES: Cc1cccc2c1[nH]cc2
• NSC Number: 618

Computed Properties

• Complexity: 122
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.6

Upstream Synthesis Route

7-Methyl-1H-indole is a versatile compound that finds wide applications in chemical synthesis. As a substituted indole derivative, it serves as a valuable building block for the synthesis of various complex molecules in the pharmaceutical, agrochemical, and material science industries.In organic synthesis, 7-Methyl-1H-indole can be used as a key intermediate in the preparation of bioactive compounds such as pharmaceutical drugs and natural products. Its unique structural features make it a crucial component in the synthesis of indole-based molecules with diverse biological activities.Furthermore, 7-Methyl-1H-indole can participate in various chemical reactions such as Friedel-Crafts acylation, nucleophilic substitution, and transition metal-catalyzed couplings. These reactions enable the functionalization of the indole ring, allowing for the creation of novel molecules with tailored properties.Overall, the application of 7-Methyl-1H-indole in chemical synthesis offers chemists a valuable tool for the construction of complex molecules with potential applications in drug discovery, materials science, and other fields of research.

Literature

• Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.

  Journal of medicinal chemistry 20110113

• An odorant receptor from the southern house mosquito Culex pipiens quinquefasciatus sensitive to oviposition attractants.

  PloS one 20100101

• Isothiocyanate NB7M causes selective cytotoxicity, pro-apoptotic signalling and cell-cycle regression in ovarian cancer cells.

  British journal of cancer 20081202

• A novel indole ethyl isothiocyanate (7Me-IEITC) with anti-proliferative and pro-apoptotic effects on platinum-resistant human ovarian cancer cells.

  Gynecologic oncology 20080501

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis.

  Journal of medicinal chemistry 20040603