94-15-5 | Dimethocaine

Availability
Typically In Stock

Description

• Catalog Number: AB72905
• Chemical Name: Dimethocaine
• CAS Number: 94-15-5
• Molecular Formula: C16H26N2O2
• Molecular Weight: 278.3898
• MDL Number: MFCD01697030
• SMILES: CCN(CC(COC(=O)c1ccc(cc1)N)(C)C)CC
• NSC Number: 68927

Computed Properties

• Complexity: 293
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 8
• XLogP3: 3.1

Literature

• Contribution of human esterases to the metabolism of selected drugs of abuse.

  Toxicology letters 20150105

• Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2.

  Toxicology letters 20140210

• In vivo comparison of the reinforcing and dopamine transporter effects of local anesthetics in rhesus monkeys.

  Synapse (New York, N.Y.) 20051215

• Role of the dopamine transporter and the sodium channel in the cocaine-like discriminative stimulus effects of local anesthetics in rats.

  Psychopharmacology 20010901

• Subtle differences in the discriminative stimulus effects of cocaine and GBR-12909.

  Progress in neuro-psychopharmacology & biological psychiatry 20010401