940929-33-9 | SB 743921

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$36.00	$25.00
5mg	99%	in stock	$52.00	$36.00
50mg	99%	in stock	$259.00	$181.00
100mg	99%	in stock	$436.00	$305.00
250mg	99%	in stock	$916.00	$641.00

Description

• Catalog Number: AH85405
• Chemical Name: SB 743921
• CAS Number: 940929-33-9
• Molecular Formula: C31H34Cl2N2O3
• Molecular Weight: 553.5192599999998
• MDL Number: MFCD18385010
• SMILES: NCCCN([C@@H](c1oc2cc(Cl)ccc2c(=O)c1Cc1ccccc1)C(C)C)C(=O)c1ccc(cc1)C.Cl

Computed Properties

• Complexity: 813
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 38
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9

Literature

• Discovery of (+)-N-(3-aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a kinesin spindle protein inhibitor and potential anticancer agent.

  Journal of medicinal chemistry 20111013

• A first in human study of SB-743921, a kinesin spindle protein inhibitor, to determine pharmacokinetics, biologic effects and establish a recommended phase II dose.

  Cancer chemotherapy and pharmacology 20110201