948557-43-5 | Tie2 kinase-IN-1

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$50.00	$35.00
10mg	98%	in stock	$106.00	$74.00
50mg	98%	in stock	$232.00	$163.00

Description

• Catalog Number: AX01006
• Chemical Name: Tie2 kinase-IN-1
• CAS Number: 948557-43-5
• Molecular Formula: C26H21N3O2S
• Molecular Weight: 439.5288
• MDL Number: MFCD14585804
• SMILES: COc1ccc2c(c1)ccc(c2)c1[nH]c(nc1c1ccncc1)c1ccc(cc1)S(=O)C

Computed Properties

• Complexity: 635
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• Undefined Atom Stereocenter Count: 1
• XLogP3: 4.3

Literature

• Efficacy of Tie2 receptor antagonism in angiosarcoma.

  Neoplasia (New York, N.Y.) 20120201

• Optimization of triarylimidazoles for Tie2: influence of conformation on potency.

  Bioorganic & medicinal chemistry letters 20071015

• Pyridinylimidazole inhibitors of Tie2 kinase.

  Bioorganic & medicinal chemistry letters 20070901