949-99-5 | 4-Nitro-L-phenylalanine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$15.00	$11.00
5g	97%	in stock	$26.00	$18.00
25g	97%	in stock	$34.00	$24.00
100g	97%	in stock	$59.00	$42.00
500g	97%	in stock	$151.00	$106.00

Description

• Catalog Number: AI63768
• Chemical Name: 4-Nitro-L-phenylalanine
• CAS Number: 949-99-5
• Molecular Formula: C9H10N2O4
• Molecular Weight: 210.1867
• MDL Number: MFCD00051221
• SMILES: OC(=O)C(Cc1ccc(cc1)[N+](=O)[O-])N

Computed Properties

• Complexity: 243
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: -1.2

Literature

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  Biomedical chromatography : BMC 20120101

• Pluripotentialities of a quenched fluorescent peptide substrate library: enzymatic detection, characterization, and isoenzymes differentiation.

  Analytical biochemistry 20111215

• Development of [Ile⁴⁰]HTLV-I protease inhibition assay using novel fluorogenic and chromogenic substrate.

  Journal of peptide science : an official publication of the European Peptide Society 20110801

• Nitro-phenylalanine: a novel sensor for heat transfer in peptides.

  The journal of physical chemistry. A 20110324

• Probing local environments with the infrared probe: L-4-nitrophenylalanine.

  The journal of physical chemistry. B 20110317

• Genetic incorporation of unnatural amino acids into proteins in Mycobacterium tuberculosis.

  PloS one 20100101

• Low-molecular-weight aldehyde inhibitors of cathepsin G.

  Protein and peptide letters 20090101

• Catalytic water co-existing with a product peptide in the active site of HIV-1 protease revealed by X-ray structure analysis.

  PloS one 20090101

• Effect of electron-donating and electron-withdrawing groups on peptide/single-walled carbon nanotube interactions.

  Journal of the American Chemical Society 20071128

• New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P(1) selected by combinatorial chemistry methods.

  Molecular diversity 20070501

• Design of carrier tRNAs and selection of four-base codons for efficient incorporation of various nonnatural amino acids into proteins in Spodoptera frugiperda 21 (Sf21) insect cell-free translation system.

  Journal of bioscience and bioengineering 20061201

• Insertion of an internal dipeptide into PNA oligomers: thermal melting studies and further functionalization.

  Bioorganic & medicinal chemistry letters 20060601

• The genetic incorporation of a distance probe into proteins in Escherichia coli.

  Journal of the American Chemical Society 20060412

• Efficient incorporation of a nonnatural amino acid into a protein in an insect cell-free translation system.

  Nucleic acids symposium series (2004) 20060101

• Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex.

  The Biochemical journal 20050715

• Differential spatial approximation between cholecystokinin residue 30 and receptor residues in active and inactive conformations.

  Molecular pharmacology 20050601

• Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.

  Biochemistry 20050215

• Synthesis of new bivalent peptides for applications in the Affinity Enhancement System.

  Bioconjugate chemistry 20050101

• DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution.

  PLoS biology 20040701

• New synthetic pathway to diverse 2-substituted quinolines based on a multicomponent reaction: solution-phase and solid-phase applications.

  Journal of combinatorial chemistry 20040101

• A novel competitive ELISA for both free and protein-bound nitrotyrosine.

  Hybridoma and hybridomics 20031201

• Position-specific incorporation of a fluorophore-quencher pair into a single streptavidin through orthogonal four-base codon/anticodon pairs.

  Journal of the American Chemical Society 20021211

• Highly sensitive and selective fluorescence assays for rapid screening of endothelin-converting enzyme inhibitors.

  The Biochemical journal 20010615

• Increase in fluorescence upon the hydrolysis of tyrosine peptides: application to proteinase assays.

  Analytical biochemistry 19950501

• Sensitive, soluble chromogenic substrates for HIV-1 proteinase.

  The Journal of biological chemistry 19900515

• Comparison of mu-, delta- and kappa-receptor binding sites through pharmacologic evaluation of p-nitrophenylalanine analogs of opioid peptides.

  Life sciences 19830101