95713-52-3 | Marfey's reagent

Packsize	Purity	Availability	Price	Discounted Price
100mg	>98.0%(HPLC)	in stock	$32.00	$22.00
1g	≥97%	in stock	$43.00	$30.00
5g	≥97%	in stock	$158.00	$110.00

Description

• Catalog Number: AB42957
• Chemical Name: Marfey's reagent
• CAS Number: 95713-52-3
• Molecular Formula: C9H9FN4O5
• Molecular Weight: 272.1900
• MDL Number: MFCD00042049
• SMILES: NC(=O)[C@@H](Nc1cc(F)c(cc1[N+](=O)[O-])[N+](=O)[O-])C

Computed Properties

• Complexity: 382
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 1.6

Literature

• A universal HPLC-MS method to determine the stereochemistry of common and unusual amino acids.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Indirect reversed-phase high-performance liquid chromatographic and direct thin-layer chromatographic enantioresolution of (R,S)-Cinacalcet.

  Biomedical chromatography : BMC 20110601

• Indirect enantioresolution of (R,S)-mexiletine by reversed-phase high-performance liquid chromatography via diastereomerization with [(S,S)-O,O'-di-p-toluoyl tartaric acid anhydride], (S)-naproxen and nine chiral reagents synthesized as variants of Marfey's reagent.

  Biomedical chromatography : BMC 20110301

• Fast chiral separation of drugs using columns packed with sub-2 microm particles and ultra-high pressure.

  Chirality 20100301

• A liquid chromatography-tandem mass spectrometry assay for Marfey's derivatives of L-Ala, D-Ala, and D-Ala-D-Ala: application to the in vivo confirmation of alanine racemase as the target of cycloserine in Escherichia coli.

  Analytical biochemistry 20100101

• Reversed-phase liquid chromatographic determination of enantiomers of atenolol in rat plasma using derivatization with Marfey's reagent.

  Biomedical chromatography : BMC 20090701

• Reversed-phase high performance liquid chromatographic separation of diastereomers of beta-amino alcohols and microwave assisted synthesis of Marfey's reagent, its chiral variants and diastereomers.

  Journal of chromatography. A 20090320

• Chromatographic separation of enantiomers of non-protein alpha-amino acids after derivatization with Marfey's reagent and its four variants.

  Amino acids 20090301

• Indirect resolution of baclofen enantiomers from pharmaceutical dosage form by reversed-phase liquid chromatography after derivatization with Marfey's reagent and its structural variants.

  Biomedical chromatography : BMC 20080801

• Indirect resolution of enantiomers of penicillamine by TLC and HPLC using Marfey's reagent and its variants.

  Biomedical chromatography : BMC 20071001

• Analysis of monoethanolamine by derivatization with Marfey's reagent and HPLC.

  Journal of chromatographic science 20070301

• Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201

• Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis.

  Journal of natural products 20050601

• Marfey's reagent for chiral amino acid analysis: a review.

  Amino acids 20041201

• Chirality determination of unusual amino acids using precolumn derivatization and liquid chromatography-electrospray ionization mass spectrometry.

  Journal of chromatography. A 20040507

• Acid hydrolysis of silk fibroins and determination of the enrichment of isotopically labeled amino acids using precolumn derivatization and high-performance liquid chromatography-electrospray ionization-mass spectrometry.

  Analytical biochemistry 20021201

• High-performance liquid chromatographic enantioseparation of beta-amino acids.

  Journal of chromatography. A 20010817