98-18-0 | 3-Aminobenzenesulfonamide

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$19.00	$13.00
25g	98%	in stock	$42.00	$30.00
100g	98%	in stock	$113.00	$79.00
500g	95%	in stock	$381.00	$267.00

Description

• Catalog Number: AC74770
• Chemical Name: 3-Aminobenzenesulfonamide
• CAS Number: 98-18-0
• Molecular Formula: C6H8N2O2S
• Molecular Weight: 172.2049
• MDL Number: MFCD00035781
• SMILES: Nc1cccc(c1)S(=O)(=O)N
• NSC Number: 7542

Computed Properties

• Complexity: 219
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.4

Literature

• Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

  Bioorganic & medicinal chemistry 20110601

• 3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors.

  Bioorganic & medicinal chemistry letters 20100515

• Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.

  Bioorganic & medicinal chemistry 20091015

• Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides.

  Bioorganic & medicinal chemistry letters 20090901

• Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides.

  Bioorganic & medicinal chemistry letters 20070915

• QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach.

  Bioorganic & medicinal chemistry letters 20060401

• Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides.

  Bioorganic & medicinal chemistry 20051115

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.

  Bioorganic & medicinal chemistry letters 20051101

• Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

  Bioorganic & medicinal chemistry letters 20050901

• Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.

  Bioorganic & medicinal chemistry letters 20050215

• Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.

  Bioorganic & medicinal chemistry letters 20041220

• Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.

  Bioorganic & medicinal chemistry letters 20040621

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.

  Bioorganic & medicinal chemistry letters 20040503

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

  Bioorganic & medicinal chemistry letters 20030324

• Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

  Journal of medicinal chemistry 20020328

• [Reaction of 2-4-aminobenzensulfonamide structures with thymol-sodium hypochlorite].

  Die Pharmazie 20010501

• Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.

  Bioorganic & medicinal chemistry letters 20010226