98-54-4 | 4-tert-Butylphenol

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$13.00	$9.00
25g	98%	in stock	$19.00	$13.00
500g	98%	in stock	$29.00	$21.00

Description

• Catalog Number: AB68359
• Chemical Name: 4-tert-Butylphenol
• CAS Number: 98-54-4
• Molecular Formula: C10H14O
• Molecular Weight: 150.2176
• MDL Number: MFCD00002367
• SMILES: CC(c1ccc(cc1)O)(C)C
• NSC Number: 3697

Computed Properties

• Complexity: 115
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 3.3

Literature

• Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20180201

• Reduced Nrf2 activation in PI3K phosphorylation-impaired vitiliginous keratinocytes increases susceptibility to ROS-generating chemical-induced apoptosis.

  Environmental toxicology 20171201

• Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8.

  The Journal of investigative dermatology 20121101

• Programed nebulizing-gas pressure mode for quantitative capillary electrophoresis-mass spectrometry analysis of endocrine disruptors in honey.

  Electrophoresis 20120801

• Multiple headspace-solid-phase microextraction as a powerful tool for the quantitative determination of volatile radiolysis products in a multilayer food packaging material sterilized with γ-radiation.

  Journal of chromatography. A 20120629

• Determination of endocrine-disrupting phenols in water samples by a new manual shaking-enhanced, ultrasound-assisted emulsification microextraction method.

  The Analyst 20120507

• Determination of phenols with ion chromatography-online electrochemical derivatization based on porous electrode-fluorescence detection.

  Journal of chromatography. A 20120316

• Bra-associated allergic contact dermatitis: p-tert-butylphenol formaldehyde resin as the culprit.

  Pediatric dermatology 20120101

• Comparative study of IQ-ultra and Finn Chambers test methodologies in detecting 10 common standard allergens that cause allergic contact dermatitis.

  Journal of cutaneous medicine and surgery 20120101

• p-tert-Butylphenol formaldehyde resin and its impact on children.

  Dermatitis : contact, atopic, occupational, drug 20120101

• Allergic contact dermatitis to p-tert butylphenol formaldehyde resin in a continuous positive airway pressure strap.

  Dermatitis : contact, atopic, occupational, drug 20120101

• Removal of BPA model compounds and related substances by means of column chromatography using Octolig®.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

• Solid phase analytical derivatization of anthropogenic and natural phenolic estrogen mimics with pentafluoropyridine for gas chromatography-mass spectrometry.

  Journal of chromatography. A 20111223

• Do commercially available metal salts mediate calixarene formation via hydrogen-bonded dimers?

  The Journal of organic chemistry 20110902

• Preparation of metal wire supported solid-phase microextraction fiber coated with multi-walled carbon nanotubes.

  Journal of separation science 20110901

• New perspectives on the role of vitiligo in immune responses to melanoma.

  Oncotarget 20110901

• Removal of alkylphenols from polluted sites using surfactant-assisted soil washing and photocatalysis.

  Environmental science and pollution research international 20110601

• Dirhodium-catalyzed phenol and aniline oxidations with T-HYDRO. Substrate scope and mechanism of oxidation.

  The Journal of organic chemistry 20110415

• Topical application of bleaching phenols; in-vivo studies and mechanism of action relevant to melanoma treatment.

  Melanoma research 20110401

• [Induction of occupational leucoderma and vitiligo. Can butylated hydroxytoluene induce vitiligo similarly to p-tert-butylphenol?].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20110301

• Application of liquid-liquid-liquid microextraction and high-performance liquid chromatography for the determination of alkylphenols and bisphenol-A in water.

  Journal of separation science 20110201

• Potential utility of natural products as regulators of breast cancer-associated aromatase promoters.

  Reproductive biology and endocrinology : RB&E 20110101

• Vitiligo: a review of some facts lesser known about depigmentation.

  Indian journal of dermatology 20110101

• Safety and efficacy evaluation of TRUE TEST panels 1.1, 2.1, and 3.1 in children and adolescents.

  Dermatitis : contact, atopic, occupational, drug 20110101

• Chemical category approach of genotoxicity studies for branched alkylphenols.

  Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20110101

• Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.

  Chemico-biological interactions 20101205

• Determination of antioxidants in new and used lubricant oils by headspace-programmed temperature vaporization-gas chromatography-mass spectrometry.

  Analytical and bioanalytical chemistry 20101201

• Excited-state photodynamics of perylene-porphyrin dyads. 5. Tuning light-harvesting characteristics via perylene substituents, connection motif, and three-dimensional architecture.

  The journal of physical chemistry. B 20101118

• Effect-directed investigation and interactive effect of organic toxicants in landfill leachates combining Microtox test with RP-HPLC fractionation and GC/MS analysis.

  Ecotoxicology (London, England) 20101001

• Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment.

  Applied and environmental microbiology 20101001

• Allergic contact dermatitis caused by p-tert-butylphenol formaldehyde resin and colophonium in neoprene thermal sauna shorts.

  Contact dermatitis 20101001

• Semivolatile endocrine-disrupting compounds in paired indoor and outdoor air in two northern California communities.

  Environmental science & technology 20100901

• Various aspects of piscine toxicology.

  Interdisciplinary toxicology 20100901

• Experimental evidence of a delta-shock in nonlinear chromatography.

  Journal of chromatography. A 20100326

• Dispersive liquid-liquid microextraction versus single-drop microextraction for the determination of several endocrine-disrupting phenols from seawaters.

  Talanta 20100315

• 4-[(E)-(5-tert-Butyl-2-hydroxy-phen-yl)diazen-yl]benzoic acid benzene hemisolvate.

  Acta crystallographica. Section E, Structure reports online 20100301

• Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.

  Toxicology letters 20100215

• Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: relevance to skin depigmentation.

  The Journal of investigative dermatology 20100101

• Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG.

  PloS one 20100101

• The Hand Eczema Trial (HET): Design of a randomised clinical trial of the effect of classification and individual counselling versus no intervention among health-care workers with hand eczema.

  BMC dermatology 20100101

• Chemical leucoderma: Indian scenario, prognosis, and treatment.

  Indian journal of dermatology 20100101

• Chemical leukoderma: what's new on etiopathological and clinical aspects?

  Indian journal of dermatology 20100101

• Synthesis, structure and ethylene polymerisation behaviour of vanadium(IV and V) complexes bearing chelating aryloxides.

  Dalton transactions (Cambridge, England : 2003) 20091107

• Determination of endocrine disrupting compounds using temperature-dependent inclusion chromatography: I. Optimization of separation protocol.

  Journal of chromatography. A 20091030

• Effects of environmental relevant doses of pollutants from offshore oil production on Atlantic cod (Gadus morhua).

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090801

• Determination of dimethyl fumarate and other potential allergens in desiccant and antimould sachets.

  Analytical and bioanalytical chemistry 20090801

• Evaluation of skin diseases and disorders in photographers.

  Indian journal of occupational and environmental medicine 20090801

• Increase in the levels of chaperone proteins by exposure to beta-estradiol, bisphenol A and 4-methoxyphenol in human cells transfected with estrogen receptor alpha cDNA.

  Toxicology in vitro : an international journal published in association with BIBRA 20090601

• Synthesis of diazacalix[8]arene and triazacalix[12]arene methyl ethers via intramolecular aryl amination.

  Organic letters 20090219

• Uptake and tissue distribution of C4-C7 alkylphenols in Atlantic cod (Gadus morhua): relevance for biomonitoring of produced water discharges from oil production.

  Marine pollution bulletin 20090101

• [Influence of p-tert-butylphenol on immunity of mice].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20090101

• Reactivity of a 10-I-3 hypervalent iodine trifluoromethylation reagent with phenols.

  The Journal of organic chemistry 20081003

• A study on the synthesis of calix[4 and 6]arenes using alternately arranged phloroglucinols and p-tert-butylphenols.

  Chemical & pharmaceutical bulletin 20080801

• Determination of p-tert-octylphenol in blood and tissues by gas chromatography coupled with mass spectrometry.

  Journal of analytical toxicology 20080501

• Characterization of alkylphenol metabolites in fish bile by enzymatic treatment and HPLC-fluorescence analysis.

  Chemosphere 20080401

• 4-Alkylphenols and related chemicals show similar effect on the function of human and rat estrogen receptor alpha in reporter gene assay.

  Chemosphere 20080301

• A review of 241 subjects who were patch tested twice: could fragrance mix I cause active sensitization?

  The British journal of dermatology 20080301

• Structure and vibrational spectrum of the hydrogen-bonded system between 4-tert-butylphenol and N-bases: Ab initio and DFT studies.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080201

• Uptake of some selected aquatic pollutants in semipermeable membrane devices (SPMDs) and the polar organic chemical integrative sampler (POCIS).

  Journal of environmental monitoring : JEM 20080201

• Three-dimensional mesoporous gallosilicate with Pm3n symmetry and its unusual catalytic performances.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Contact allergy to p-tert-butylphenol formaldehyde resin and zinc diethyldithiocarbamate in a wet suit.

  Dermatitis : contact, atopic, occupational, drug 20080101

• Shoe allergens: retrospective analysis of cross-sectional data from the north american contact dermatitis group, 2001-2004.

  Dermatitis : contact, atopic, occupational, drug 20071201

• Monitoring of environmental phenolic endocrine disrupting compounds in treatment effluents and river waters, Korea.

  Talanta 20071015

• Binding of alkylphenols and alkylated non-phenolics to the rainbow trout (Oncorhynchus mykiss) plasma sex steroid-binding protein.

  Ecotoxicology and environmental safety 20070901

• Anaerobic biodegradation of 4-alkylphenols in a paddy soil microcosm supplemented with nitrate.

  Chemosphere 20070801

• Anaerobic co-metabolic oxidation of 4-alkylphenols with medium-length or long alkyl chains by Thauera sp., strain R5.

  Applied microbiology and biotechnology 20070701

• [Degradation of endocrine disrupting chemicals(EDCs)-BP by combination of UV/ micro-aeration process and impact factors].

  Huan jing ke xue= Huanjing kexue 20070701

• [Kinetics of endocrine disrupting chemical 4-tert-butylphenol during chlorination in aqua].

  Huan jing ke xue= Huanjing kexue 20070701

• Shoe dermatitis from para-tertiary butylphenol formaldehyde.

  Contact dermatitis 20070501

• Effects of alkylphenols on glycerophospholipids and cholesterol in liver and brain from female Atlantic cod (Gadus morhua).

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070401

• An expedient one-pot synthesis of para-tert-butylcalix[8]- and [9]arene.

  Chemical communications (Cambridge, England) 20070307

• Molecular and electronic structure of square-planar gold complexes containing two 1,2-Di(4-tert-butylphenyl)ethylene-1,2-dithiolato ligands: [Au(2L)2]1+/0/1-/2-. A combined experimental and computational study.

  Inorganic chemistry 20070219

• Pharmacological properties of BN82451: a novel multitargeting neuroprotective agent.

  CNS drug reviews 20070101

• Determination of endocrine-disrupting compounds in cereals by pressurized liquid extraction and liquid chromatography-mass spectrometry. Study of background contamination.

  Journal of chromatography. A 20061229

• Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

  Journal of molecular graphics & modelling 20061101

• A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo.

  The American journal of pathology 20061101

• Aerobic and anaerobic biodegradation of phenol derivatives in various paddy soils.

  The Science of the total environment 20060831

• European Standard Series patch test results from a contact dermatitis clinic in Israel during the 7-year period from 1998 to 2004.

  Contact dermatitis 20060801

• Allergic contact dermatitis due to orthopedic shoes and a prosthesis for an amputated foot.

  Contact dermatitis 20060801

• Effluents from oil production activities contain chemicals that interfere with normal function of intra- and extra-cellular estrogen binding proteins.

  Marine environmental research 20060701

• Effect of the endcapping of reversed-phase high-performance liquid chromatography adsorbents on the adsorption isotherm.

  Journal of chromatography. A 20051209

• Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

  Journal of medicinal chemistry 20050908

• Estrogenic effects of environmental chemicals: an interspecies comparison.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050701

• Stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography--mass spectrometry for measurement of phenolic xenoestrogens in human urine samples.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050605

• Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

  Journal of medicinal chemistry 20050505

• In vitro effects of diethylstilbestrol, genistein, 4-tert-butylphenol, and 4-tert-octylphenol on steroidogenic activity of isolated immature rat ovarian follicles.

  Toxicology and applied pharmacology 20050401

• 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.

  The Journal of investigative dermatology 20050401

• Allergic contact dermatitis in Iran.

  Contact dermatitis 20050301

• 1,3-Alternate calix[4]arenes, selectively functionalized by amino groups.

  Organic & biomolecular chemistry 20050107

• Water purification through bioconversion of phenol compounds by tyrosinase and chemical adsorption by chitosan beads.

  Biotechnology progress 20050101

• [Estimation of daily intake of phenols in hospital meal samples].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041201

• Determination of weakly acidic endocrine-disrupting compounds by liquid chromatography-mass spectrometry with post-column base addition.

  Journal of chromatography. A 20041112

• Azolium-linked cyclophanes: a comprehensive examination of conformations by 1H NMR spectroscopy and structural studies.

  The Journal of organic chemistry 20041029

• Indoor air pollution by alkylphenols in Tokyo.

  Indoor air 20041001

• Photodegradation of bisphenol-A with TiO2 immobilized on the glass tubes including the UV light lamps.

  Water research 20040901

• Effects of alkylphenols on redox status in first spawning Atlantic cod (Gadus morhua).

  Aquatic toxicology (Amsterdam, Netherlands) 20040730

• Trace analysis of phenolic xenoestrogens in water samples by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography-mass spectrometry.

  Journal of chromatography. A 20040702

• Simultaneous determination of alkylphenols and bisphenol A in river water by stir bar sorptive extraction with in situ acetylation and thermal desorption-gas chromatography-mass spectrometry.

  Journal of chromatography. A 20040604

• Effects of alkylphenols on CYP1A and CYP3A expression in first spawning Atlantic cod (Gadus morhua).

  Aquatic toxicology (Amsterdam, Netherlands) 20040512

• Allergic contact dermatitis to mango flesh.

  International journal of dermatology 20040301

• Band splitting in overloaded isocratic elution chromatography III. Modeling of adsorbate-adsorbate interactions by a two-component extension of a BET kinetic isotherm model.

  Journal of chromatography. A 20040227

• Comparative study of the uterotrophic potency of 14 chemicals in a uterotrophic assay and their receptor-binding affinity.

  Toxicology letters 20040115

• Effect of deoxyarbutin on melanogenesis: in vivo comparison with other melanogenesis inhibitor.

  Journal of cosmetic science 20040101

• An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002.

  Contact dermatitis 20040101

• Characterization of calixarene- and resorcinarene-bonded stationary phases. I. Hydrophobic interactions.

  Journal of chromatography. A 20031222

• Simultaneous measurement of urinary bisphenol A and alkylphenols by automated solid-phase extractive derivatization gas chromatography/mass spectrometry.

  Analytical chemistry 20031215

• Synthesis and beta-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine: identification of beta 3-antagonists.

  Bioorganic & medicinal chemistry 20031117

• Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust.

  Environmental science & technology 20031015

• Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

  Chemical research in toxicology 20031001

• Comparison between adsorption isotherm determination techniques and overloaded band profiles on four batches of monolithic columns.

  Journal of chromatography. A 20030919

• Common allergens in shoe dermatitis: our experience in Lahore, Pakistan.

  International journal of dermatology 20030801

• Band splitting in overloaded isocratic elution chromatography I. The experimental evidence.

  Journal of chromatography. A 20030801

• Band splitting in overloaded isocratic elution chromatography II. New competitive adsorption isotherms.

  Journal of chromatography. A 20030801

• Preparation of uniformly sized molecularly imprinted polymers for phenolic compounds and their application to the assay of bisphenol A in river water.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030501

• Lymphomatoid contact dermatitis to para-tertyl-butyl phenol resin.

  Clinical and experimental dermatology 20030501

• Quantitative structure-activity relationships for estrogen receptor binding affinity of phenolic chemicals.

  Water research 20030301

• Shoe contact dermatitis in Israel.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030301

• On-column concentration of bisphenol A with one-step removal of humic acids in water.

  Journal of chromatography. A 20030214

• Contact dermatitis from electrocardiograph-monitoring electrodes: role of p-tert-butylphenol-formaldehyde resin.

  Contact dermatitis 20030201

• [Improved method for determining bisphenol A in polycarbonate products without using dichloromethane].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20030201

• Alkylphenol and bisphenol A levels in rubber products.

  Food additives and contaminants 20030101

• Apoptosis regulators and responses in human melanocytic and keratinocytic cells.

  The Journal of investigative dermatology 20030101

• Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat.

  Reproductive toxicology (Elmsford, N.Y.) 20030101

• Low-molecular-weight contact allergens in p-tert-butylphenol-formaldehyde resin.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20021201

• Comparison of the adsorption equilibrium of a few low-molecular mass compounds on a monolithic and a packed column in reversed-phase liquid chromatography.

  Journal of chromatography. A 20021129

• Permeability characteristics of endocrine-disrupting chemicals using an in vitro cell culture model, Caco-2 cells.

  Current drug metabolism 20021001

• Synthesis and photophysical properties of light-harvesting arrays comprised of a porphyrin bearing multiple perylene-monoimide accessory pigments.

  The Journal of organic chemistry 20020906

• Contact allergy to the monomers in p-tert-butylphenol-formaldehyde resin.

  Contact dermatitis 20020901

• Sensitizing capacity of some trimers in p-tert-butylphenol-formaldehyde resin.

  Contact dermatitis 20020701

• Relevance of chemical structure and cytotoxicity to the induction of chromosome aberrations based on the testing results of 98 high production volume industrial chemicals.

  Mutation research 20020527

• Mechanistic implications of variable stoichiometries of oxygen consumption during tyrosinase catalyzed oxidation of monophenols and o-diphenols.

  Biochimica et biophysica acta 20020520

• Characterization of paint samples used in drinking water reservoirs: identification of endocrine disruptor compounds.

  Journal of chromatographic science 20020401

• Brominated phenols: characterization of estrogen-like activity in the human breast cancer cell-line MCF-7.

  Toxicology letters 20020324

• Comparative evaluation of alkylphenolic compounds on estrogenic activity in vitro and in vivo.

  Journal of toxicology and environmental health. Part A 20020301

• Determination of phenolic xenoestrogens in water by liquid chromatography with coulometric-array detection.

  Journal of chromatography. A 20020208

• Developmental aspects of human hepatic drug glucuronidation in young children and adults.

  Gut 20020201

• The effect of race and ethnicity on patch test results.

  Journal of the American Academy of Dermatology 20020201

• Sensitizing capacity of two monomeric aldehyde components in p-tert-butylphenol-formaldehyde resin.

  Acta dermato-venereologica 20020101

• Molecular recognition by beta-cyclodextrin derivatives: FEP vs MM/PBSA study.

  Combinatorial chemistry & high throughput screening 20011201

• Comparative metabolism, covalent binding and toxicity of BHT congeners in rat liver slices.

  Chemico-biological interactions 20011128

• Effects of bisphenol A and its derivatives on the response of GABA(A) receptors expressed in Xenopus oocytes.

  Bioscience, biotechnology, and biochemistry 20010901

• Tyrosinase action on monophenols: evidence for direct enzymatic release of o-diphenol.

  Biochimica et biophysica acta 20010813

• Column silylation method for determining endocrine disruptors from environmental water samples by solid phase micro-extraction.

  Talanta 20010706

• Altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): upregulation of the A2b adenosine receptor 1.

  The Journal of investigative dermatology 19991101

• Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications.

  Pharmacogenetics 19971201

• Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4.

  Archives of biochemistry and biophysics 19970815

• A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.

  Molecular pharmacology 19940101

• Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner.

  Contact dermatitis 19930301