98-59-9 | P-Toluenesulfonyl chloride

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$12.00	$8.00
25g	98%	in stock	$15.00	$10.00
100g	98%	in stock	$20.00	$14.00
250g	98%	in stock	$36.00	$25.00
500g	98%	in stock	$50.00	$35.00

Description

• Catalog Number: AB46947
• Chemical Name: P-Toluenesulfonyl chloride
• CAS Number: 98-59-9
• Molecular Formula: C7H7ClO2S
• Molecular Weight: 190.6473
• MDL Number: MFCD00007450
• SMILES: Cc1ccc(cc1)S(=O)(=O)Cl
• NSC Number: 175822

Computed Properties

• Complexity: 209
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3

Literature

• Synthesis, X-ray structural, characterization, NBO and HOMO-LUMO analysis using DFT study of 4-methyl-N-(naphthalene-1-yl)benzene sulfonamide.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• Synthesis and properties of optically active nanostructured polymers bearing amino acid moieties by direct polycondensation of 4,4'-thiobis(2-tert-butyl-5-methylphenol) with chiral diacids.

  Amino acids 20120601

• 9,10-Dioxoanthracene-1,4-diyl bis-(4-methyl-benzene-sulfonate).

  Acta crystallographica. Section E, Structure reports online 20120501

• Synthesis of new sulfonamides as lipoxygenase inhibitors.

  Bioorganic & medicinal chemistry 20120415

• N-(2-Formyl-phen-yl)-4-toluene-sulfonamide: a second monoclinic polymorph.

  Acta crystallographica. Section E, Structure reports online 20120401

• 3-De-oxy-1,2-di-O-isopropyl-idene-5-O-tosyl-d-threo-pentofuran-ose.

  Acta crystallographica. Section E, Structure reports online 20120401

• N,N'-[1,3-Phenyl-enebis(methyl-ene)]di-p-toluenesulfonamide.

  Acta crystallographica. Section E, Structure reports online 20120401

• N-(2-Amino-pyridin-3-yl)-4-methyl-N-(4-methyl-phenyl-sulfon-yl)benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20120401

• A diastereoselective, nucleophile-promoted aldol-lactonization of ketoacids leading to bicyclic-β-lactones.

  The Journal of organic chemistry 20120302

• Development and validation of an HPLC-DAD method for quantification of bornesitol in extracts from Hancornia speciosa leaves after derivatization with p-toluenesulfonyl chloride.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120301

• (E)-3-Phenyl-2-(1-tosyl-1H-indol-3-ylcarbon-yl)acrylonitrile.

  Acta crystallographica. Section E, Structure reports online 20120301

• Iron-catalyzed regio- and stereoselective chlorosulfonylation of terminal alkynes with aromatic sulfonyl chlorides.

  Organic letters 20120203

• Tosylated and azidated inulins as key substrates for further chemical modifications to access inulin-based advanced materials: an inulin-based glycocluster.

  Bioorganic & medicinal chemistry letters 20120115

• Application of the dissociative electron transfer theory and its extension to the case of in-cage interactions in the electrochemical reduction of arene sulfonyl chlorides.

  Physical chemistry chemical physics : PCCP 20120107

• Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting.

  International journal of nanomedicine 20120101

• Synthesis of new bitopic tetra(pyrazolyl)-ligands with neopentane and O-xylene backbones.

  TheScientificWorldJournal 20120101

• N-[7-Eth-oxy-2-(prop-2-en-1-yl)-2H-indazol-6-yl]-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20111201

• A study of anhydrocelluloses--is a cellulose structure with residues in a 1C4-conformation more prone to hydrolysis?

  Organic & biomolecular chemistry 20111107

• Synthesis of biodegradable chiral poly(ester-imide)s derived from valine-, leucine- and tyrosine-containing monomers.

  Amino acids 20111101

• 3-(Trimethyl-sil-yl)prop-2-ynyl p-toluene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Preparation of nucleosides derived from 2-nitroimidazole and D-arabinose, D-ribose, and D-galactose by the Vorbrüggen method and their conversion to potential precursors for tracers to image hypoxia.

  The Journal of organic chemistry 20111021

• Fabrication of potential macromolecular prodrugs of aspirin and diclofenac with dextran.

  Pakistan journal of pharmaceutical sciences 20111001

• N-(2-Bromo-phen-yl)-4-methyl-N-(4-methyl-phen-ylsulfon-yl)benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110901

• N-(2,4-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110901

• 1-(4-Methyl-phenyl-sulfon-yl)-5-phenyl-4,5-dihydro-1H-pyrazole.

  Acta crystallographica. Section E, Structure reports online 20110801

• N-[2-(3,4-Dimeth-oxy-phen-yl)eth-yl]-N,4-dimethyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110801

• Treatment of alcohols with tosyl chloride does not always lead to the formation of tosylates.

  Molecules (Basel, Switzerland) 20110701

• N-[7-Eth-oxy-1-(prop-2-en-1-yl)-1H-indazol-4-yl]-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110701

• 4-[(4-Methyl-benzene-sulfonamido)-meth-yl]cyclo-hexa-necarb-oxy-lic acid.

  Acta crystallographica. Section E, Structure reports online 20110701

• 2-(Thio-phen-2-yl)ethyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20110701

• Copper(II)-complex directed regioselective mono-p-toluenesulfonylation of cyclomaltoheptaose at a primary hydroxyl group position: an NMR and molecular dynamics-aided design.

  The journal of physical chemistry. B 20110616

• Synthesis of 4-(aminoalkyl) substituted 1,3-dioxanes as potent NMDA and σ receptor antagonists.

  European journal of medicinal chemistry 20110601

• N-(7-Eth-oxy-1H-indazol-4-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110601

• 2-Amino-pyrimidin-1-ium 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20110601

• 4-{[(4-Methyl-phen-yl)sulfon-yl]amino}-benzoic acid.

  Acta crystallographica. Section E, Structure reports online 20110401

• Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase.

  ChemMedChem 20110207

• Synthesis, characterization and in vitro antimicrobial and biodegradability study of pseudo-poly(amino acid)s derived from N,N'-(pyromellitoyl)-bis-L-tyrosine dimethyl ester as a chiral bioactive diphenolic monomer.

  Amino acids 20110201

• N-(2-Hy-droxy-1,1-dimethyl-eth-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110201

• 1-(4-Meth-oxy-phen-yl)-4-(3-nitro-phen-yl)-3-phen-oxy-azetidin-2-one.

  Acta crystallographica. Section E, Structure reports online 20110201

• N-(3,4-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110101

• N-(2,6-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110101

• N-(4-Meth-oxy-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110101

• N-(2,5-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110101

• Synthesis of tryptoline-3-carboxylic Acid derivatives a novel antidiabetic agent.

  Journal of young pharmacists : JYP 20110101

• Synthesis of dehydroepiandrosterone analogues modified with phosphatidic acid moiety.

  Steroids 20101212

• N-(2,3-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20101201

• N-(4-Chloro-pyridin-2-yl)-N-(4-methyl-phenyl-sulfon-yl)acetamide.

  Acta crystallographica. Section E, Structure reports online 20101201

• N-(4-Chloro-pyridin-2-yl)-N-meth-oxy-methyl-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20101201

• N-(2,3-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20101201

• 2,2,2-Trifluoro-ethyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20101101

• N-(2-Meth-oxy-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20101101

• [(3R,4S)-4-(4-Fluoro-phen-yl)-1-methyl-piperidin-3-yl]methyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20101001

• 4-Methyl-N-[(E)-4-methyl-1-(4-methyl-phenyl-sulfon-yl)-1,2-dihydropyridin-2-yl-idene]benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100801

• N-(3-Eth-oxy-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100701

• N-(2,6-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100501

• 3-[1-(4-Methyl-phen-ylsulfon-yl)-1,4-di-hydro-pyridin-4-yl]-1H-indole.

  Acta crystallographica. Section E, Structure reports online 20100401

• N-(p-Tolyl-sulfon-yl)-l-asparagine.

  Acta crystallographica. Section E, Structure reports online 20100301

• N-[4-(p-Toluenesulfonamido)phen-ylsulfon-yl]acetamide.

  Acta crystallographica. Section E, Structure reports online 20100201

• Methyl 2-(p-toluene-sulfonamido)benzoate.

  Acta crystallographica. Section E, Structure reports online 20100201

• Synthesis and crystal structures of multifunctional tosylates as basis for star-shaped poly(2-ethyl-2-oxazoline)s.

  Beilstein journal of organic chemistry 20100101

• N-(3,5-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100101

• N-(2,5-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100101

• N-(3-Bromo-5-methyl-2-pyrid-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20100101

• 2-(4-Methyl-benzene-sulfonamido)-2-phenyl-acetic acid.

  Acta crystallographica. Section E, Structure reports online 20091101

• N-(3,5-Dichloro-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20091001

• 2,2,4-Trimethyl-5-(4-tolyl-sulfon-yl)-2,3,4,5-tetra-hydro-1H-1,5-benzo-diazepine.

  Acta crystallographica. Section E, Structure reports online 20091001

• N,N'-Bis(2-cyano-ethyl)-4,4'-dimethyl-N,N'-(butane-1,4-di-yl)dibenzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20091001

• 3,4-O-Isopropyl-idene-2,7-di-O-p-tolyl-sulfonyl-α-l-xylo-3-heptulo-3,6-furan-osononitrile.

  Acta crystallographica. Section E, Structure reports online 20091001

• 4-(9-Anthr-yl)-1-(3-bromo-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.

  Acta crystallographica. Section E, Structure reports online 20091001

• 4-(4-Cyano-2-fluoro-phen-oxy)phenyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20090801

• 4-(9-Anthr-yl)-1-(2,4-dimethoxy-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.

  Acta crystallographica. Section E, Structure reports online 20090701

• (2S)-Methyl 2-(p-toluenesulfonamido)propanoate.

  Acta crystallographica. Section E, Structure reports online 20090601

• Amphiphilic organocatalyst for Schotten-Baumann-type tosylation of alcohols under organic solvent free condition.

  Organic letters 20090416

• N-(3,4-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20090401

• 4-(9-Anthr-yl)-1-phenylspiro-[azetidine-3,9'-xanthen]-2-one.

  Acta crystallographica. Section E, Structure reports online 20090301

• 4-(9-Anthr-yl)-1-(2-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.

  Acta crystallographica. Section E, Structure reports online 20090301

• Potent new small-molecule inhibitor of botulinum neurotoxin serotype A endopeptidase developed by synthesis-based computer-aided molecular design.

  PloS one 20090101

• 2,4-Di-tert-butyl-6-[1-(3,5-di-tert-butyl-2-hydroxy-phen-yl)eth-yl]phenyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20090101

• 1-(Phthalimidometh-yl)pyridinium p-toluene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20090101

• Capture of Escherichia coli O157:H7 Using Immunomagnetic Beads of Different Size and Antibody Conjugating Chemistry.

  Sensors (Basel, Switzerland) 20090101

• (1R,3S,5R,6S)-6-Acet-oxy-3-(4-methyl-phenyl-sulfon-yloxy)tropane.

  Acta crystallographica. Section E, Structure reports online 20081201

• 4-(9-Anthr-yl)-1-(1-naphth-yl)spiro-[azetidine-3,9'-xanthen]-2-one n-hexane hemisolvate.

  Acta crystallographica. Section E, Structure reports online 20081201

• 1,2-Bis(p-tolyl-sulfon-yl)hydrazine.

  Acta crystallographica. Section E, Structure reports online 20081101

• trans-rac-[1-Oxo-2-phenethyl-3-(2-thien-yl)-1,2,3,4-tetra-hydro-isoquinolin-4-yl]methyl 4-methyl-benzene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20081001

• 6-Formyl-2-meth-oxy-3-nitro-phenyl 4-toluene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20081001

• 2-Nitro-p-phenyl-ene bis-(toluene-sulfonate).

  Acta crystallographica. Section E, Structure reports online 20080901

• O-(tert-Butyl-dimethyl-silyl)tris-(O-4-methyl-phenyl-sulfon-yl)penta-erythritol.

  Acta crystallographica. Section E, Structure reports online 20080801

• Tetra-O-4-methyl-phenyl-sulfonyl-penta-erythritol.

  Acta crystallographica. Section E, Structure reports online 20080801

• 1-(2,3-Di-O-acetyl-4-chloro-4-de-oxy-6-O-tosyl-β-d-galactopyranos-yl)propan-2-one methanol 0.25-solvate.

  Acta crystallographica. Section E, Structure reports online 20080801

• Effect of PEG molecular weight and linking chemistry on the biological activity and thermal stability of PEGylated trypsin.

  International journal of pharmaceutics 20080605

• Ion-pair single-drop microextraction versus phase-transfer catalytic extraction for the gas chromatographic determination of phenols as tosylated derivatives.

  Journal of chromatography. A 20080509

• Affinity purification of natural ligands.

  Current protocols in protein science 20080501

• 4-(9-Anthr-yl)-1-(4-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.

  Acta crystallographica. Section E, Structure reports online 20080501

• 2-[1-(4-Ethoxy-phen-yl)-2-oxo-4-styryl-azetidin-3-yl]isoindoline-1,3-dione.

  Acta crystallographica. Section E, Structure reports online 20080501

• 4-(Methyl-sulfan-yl)-2-(p-toluene-sulfonamido)butanoic acid.

  Acta crystallographica. Section E, Structure reports online 20080401

• Synthesis of N-bridgehead heterocycles from saccharide benzimidazoles.

  Carbohydrate research 20080204

• Single hollow fiber SLM extraction of polyamines followed by tosyl chloride derivatization and HPLC determination.

  Analytica chimica acta 20080114

• Facile synthesis of mono-6-amino-6-deoxy-alpha-, beta-, gamma-cyclodextrin hydrochlorides for molecular recognition, chiral separation and drug delivery.

  Nature protocols 20080101

• Catalytic hydrochlorination of unactivated olefins with para-toluenesulfonyl chloride.

  Angewandte Chemie (International ed. in English) 20080101

• 1-Isopropyl-4-tosyl-piperazin-1-ium trifluoro-acetate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Isothiocyanates from tosyl chloride mediated decomposition of in situ generated dithiocarbamic acid salts.

  The Journal of organic chemistry 20070511

• Chemical transformation and biological activities of ambrein, a major product of ambergris from Physeter macrocephalus (sperm whale).

  Journal of natural products 20070201

• An efficient synthesis and reactions of novel indolylpyridazinone derivatives with expected biological activity.

  Molecules (Basel, Switzerland) 20070110

• Fluorescence sensing of anions based on inhibition of excited-state intramolecular proton transfer.

  The Journal of organic chemistry 20070105

• Synthesis of cationic single-isomer cyclodextrins for the chiral separation of amino acids and anionic pharmaceuticals.

  Nature protocols 20070101

• [Synthesis and characterizations of poly (ethylene glycol)-block-poly (glutamate)].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20060801

• Surface functionalization of gold nanoparticles using hetero-bifunctional poly(ethylene glycol) spacer for intracellular tracking and delivery.

  International journal of nanomedicine 20060301

• Dual mesomorphic assemblage of chitin normal acylates and rapid enthalpy relaxation of their side chains.

  Biomacromolecules 20060101

• Determination of glyphosate and its metabolite aminomethylphosphonic acid in fruit juices using supported-liquid membrane preconcentration method with high-performance liquid chromatography and UV detection after derivatization with p-toluenesulphonyl chloride.

  Journal of chromatography. A 20051104

• Total synthesis of milbemycins: a synthesis of (6R)-6-hydroxy-3,4-dihydromilbemycin E.

  Organic & biomolecular chemistry 20051021

• Point mutation detection with the sandwich method employing hydrogel nanospheres by the surface plasmon resonance imaging technique.

  Analytical biochemistry 20050415

• Preparation of C-6 substituted chitin derivatives under homogeneous conditions.

  Biomacromolecules 20050101

• Amino-functionalized ionic liquid as a nucleophilic scavenger in solution phase combinatorial synthesis.

  Journal of combinatorial chemistry 20050101

• [Synthesis and biological activities of new 1,2,4-triazol-3-one derivatives].

  Bioorganicheskaia khimiia 20050101

• Synthesis of novel acyclonucleosides analogs of pyridothienopyrimidine as antiviral agents.

  Nucleosides, nucleotides & nucleic acids 20050101

• A novel approach to substituted 2H-azirines.

  The Journal of organic chemistry 20031114

• Covalent chemistry and conformational dynamics of topologically chiral amide-based molecular knots.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030804

• Chemical modification of milk xanthine oxidase with different modifiers.

  Preparative biochemistry & biotechnology 20030801

• Efficient syntheses of 2-chloro-2'-deoxyadenosine (cladribine) from 2'-deoxyguanosine(1).

  The Journal of organic chemistry 20030207

• Silver(I) oxide mediated highly selective monotosylation of symmetrical diols. Application to the synthesis of polysubstituted cyclic ethers.

  Organic letters 20020711

• Asymmetric induction in the Neber rearrangement of simple ketoxime sulfonates under phase-transfer conditions: experimental evidence for the participation of an anionic pathway.

  Journal of the American Chemical Society 20020703

• Direct regioselective 2-O-(p-toluenesulfonylation) of sucrose.

  Carbohydrate research 20020402

• Syntheses, derivatives, solubility, and interfacial properties of 2-methyl-2-polyfluoroalkenyloxymethyl-1,3-propanediols: potential building blocks for syntheses of amphiphatic macromolecules.

  The Journal of organic chemistry 20020308

• Solid-phase synthesis of trisubsituted guanidines.

  Journal of combinatorial chemistry 20020101

• Friedel-Crafts sulfonylation in 1-butyl-3-methylimidazolium chloroaluminate ionic liquids.

  The Journal of organic chemistry 20011214

• Synthesis of 1,2-unsaturated pyranosylphosphonate nucleosides from 3,4,6-tri-O-acetyl-D-glycal.

  Die Pharmazie 20010701